Micro-dialysis sensor

Abstract

The invention discloses a micro-dialysis sensor which comprises a micro-dialysis membrane guide pipe (6), a micro-dialysis liquid guide pipe (5), a liquid inlet channel guide pipe (7) and a liquid outlet channel guide pipe (8), wherein the micro-dialysis membrane guide pipe (6) is positioned at the top end of the lower part of the micro-dialysis liquid guide pipe (5); the liquid inlet channel guide pipe (7) and the liquid outlet channel guide pipe (8) are positioned in the micro-dialysis liquid guide pipe (5); a needle electrode or a sensor is arranged in the micro-dialysis liquid guide pipe (5). The micro-dialysis sensor is applied to detecting biochemical substance concentration or electrophysiology, has the functions of observing the concentration index of the specific biochemical substance in real time and has the unparalleled advantage for tests in which detection data are required to be rapidly acquired; the micro-dialysis sensor has the function of collecting micro-dialysis liquid, can be used for detecting and verifying other later-stage biological indexes and has the function of detecting electrophysiological function signals in real time, so that an experimenter can simultaneously know the coordination of the electrophysiological and biochemical functions.

Description

technical field [0001] The invention relates to a microdialysis sensor, which is specifically used for real-time detection of biological activity while taking samples from living organisms or administering drugs. [0002] Background technique [0003] The traditional microdialysis needle is a device used for sampling and administration of living organisms. In experiments, this device will be fixed on specific experimental sites on living organisms. The dialysis needle is mainly composed of a liquid inlet channel, a liquid outlet channel and a microdialysis membrane pipeline. During the experiment, the dialysate will be poured into the microdialysis membrane pipeline through the liquid inlet channel, and then flow out through the liquid outlet channel to be collected. In the microdialysis membrane pipeline, due to the force of the concentration gradient, different high-concentration substances in the dialysate and the fluid in the living body can pass through the dialysis me...

AI Technical Summary

Problems solved by technology

[0006] 1) Defects that cannot reflect other biological activity indicators of living organisms immediately and quickly: it takes a certain time to measure the concentration of biochemical substances by collecting dialysate to make the dialysate reach the minimum measurement volume, so there is a certain time difference in the reflection of biological indicators

[0007] 2) It cannot reflect other biological characteristics at the same time, such as electrophysiological changes

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