Micro-dialysis sensor

A sensor and microdialysis technology, applied in the direction of sampling device, material electrochemical variables, etc., can solve the problems of time difference of biological indicators, low measurement volume, and inability to respond immediately and quickly, and achieve the effect of saving experimental funds and time

Inactive Publication Date: 2013-09-18
覃思
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] 1) Defects that cannot reflect other biological activity indicators of living organisms immediately and quickly: it takes a certain time to measure the concentration of biochemical substances by collecting dialysate to make the dialysate reach the minimum measurement volume, so there is a certain time difference in the reflection of biological indicators
[0007] 2) It cannot reflect other biological characteristics at the same time, such as electrophysiological changes

Method used

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  • Micro-dialysis sensor

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Embodiment Construction

[0028] A microdialysis sensor of the present invention is composed of three parts, the uppermost part is composed of a liquid inlet channel casing 1, a liquid outlet channel casing 2 and an electrode joint 3. connected part. The liquid inlet channel sleeve 1 is connected to the micro liquid sampling pump, and the dialysate enters the microdialysis sensor; the liquid outlet channel sleeve 2 is connected to the microdialysate collector, so as to collect the dialysate with biochemical substances in the body; The electrode connector 3 is connected with the potentiometer and the electric signal collector, and is used to collect the original electric signal of the concentration of physiological or biochemical substances.

[0029] The middle part of the device is the main part, which is the part connected by various pipelines, and will be closely attached to the surface of the organism in the experiment. The sensor electrode 10 contained in the electrode insulating sleeve 9 and the ...

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Abstract

The invention discloses a micro-dialysis sensor which comprises a micro-dialysis membrane guide pipe (6), a micro-dialysis liquid guide pipe (5), a liquid inlet channel guide pipe (7) and a liquid outlet channel guide pipe (8), wherein the micro-dialysis membrane guide pipe (6) is positioned at the top end of the lower part of the micro-dialysis liquid guide pipe (5); the liquid inlet channel guide pipe (7) and the liquid outlet channel guide pipe (8) are positioned in the micro-dialysis liquid guide pipe (5); a needle electrode or a sensor is arranged in the micro-dialysis liquid guide pipe (5). The micro-dialysis sensor is applied to detecting biochemical substance concentration or electrophysiology, has the functions of observing the concentration index of the specific biochemical substance in real time and has the unparalleled advantage for tests in which detection data are required to be rapidly acquired; the micro-dialysis sensor has the function of collecting micro-dialysis liquid, can be used for detecting and verifying other later-stage biological indexes and has the function of detecting electrophysiological function signals in real time, so that an experimenter can simultaneously know the coordination of the electrophysiological and biochemical functions.

Description

technical field [0001] The invention relates to a microdialysis sensor, which is specifically used for real-time detection of biological activity while taking samples from living organisms or administering drugs. [0002] Background technique [0003] The traditional microdialysis needle is a device used for sampling and administration of living organisms. In experiments, this device will be fixed on specific experimental sites on living organisms. The dialysis needle is mainly composed of a liquid inlet channel, a liquid outlet channel and a microdialysis membrane pipeline. During the experiment, the dialysate will be poured into the microdialysis membrane pipeline through the liquid inlet channel, and then flow out through the liquid outlet channel to be collected. In the microdialysis membrane pipeline, due to the force of the concentration gradient, different high-concentration substances in the dialysate and the fluid in the living body can pass through the dialysis me...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N1/10G01N27/26
Inventor 覃思
Owner 覃思
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