Preparation method of gel type styrene cation resins for chromatographic separation

Abstract

The invention provides a preparation method of gel type styrene cation resins for chromatographic separation. According to the preparation method, styrene polymer white spheres are produced by selecting a temperature rising method and reaction time in an industrially known production standard process formula of gel type styrene cation exchange resins, then a chelating agent and fluoboric acid are added in sulfuric acid during sulfonation, and chromatographic separation resins can be obtained by carrying out standard process sulfonation reaction. Compared with gel type styrene cation exchange resins which are not added with the chelating agent and the fluoboric acid during the sulfonation, the chromatographic separation resins prepared by utilizing the preparation method have the advantages that the adsorption capacity can be improved by 50%, and the mechanical strength can be improved by 20%. According to the chromatographic separation resins prepared by utilizing the preparation method, the content of fructose can be increased, the production cost can be lowered, and foreign similar products can be replaced.

Description

technical field

[0001] The invention relates to a method for producing a cation exchange resin, in particular to a method for preparing a gel-type styrene-based cation resin used for chromatographic separation. technical background

[0002] The basic principle of the chromatographic adsorption separation process is that the solid adsorbent undergoes a cyclic process consisting of specific steps in sequence. In these steps, the solid adsorbent is in contact with a fluid, and by changing the nature and composition of the fluid phase, the adsorption The agent will adsorb an adsorbate in one step (adsorption) and release the adsorbate (desorption) in the next step, usually called regeneration or elution. The process completes one cycle when the adsorption step restarts. But when the fluid phase is liquid, the regeneration step also includes adsorbent washing, backwashing and rinsing. Usually, the adsorption separation process is carried out in a fixed bed.

[0003] Fructose a...