Molecules and methods for inhibition and detection of proteins

A protein and molecular technology, applied in chemical instruments and methods, peptides containing affinity tags, peptides containing His tags, etc.
CN103547296AActive Publication Date: 2014-01-29VLAAMS INTERUNIVERSITAIR INST VOOR BIOTECHNOLOGIE VZW +3
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
VLAAMS INTERUNIVERSITAIR INST VOOR BIOTECHNOLOGIE VZW
Publication Date
2014-01-29

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Abstract

The present application belongs to the field of functional peptides and more particularly to the field of controlled protein aggregation. The invention discloses molecules of a peptide structure as defined in the claims and methods of using such molecules for therapeutic applications and for diagnostic uses, as well as in other applications such as in the agbio field and in industrial biotechnology. The molecules can be used for curing and / or stabilizing infections such as bacterial,fungal and viral diseases, but are also useful in non-infectious human and veterinary diseases. The molecules can also be used for the detection of protein biomarkers and for the prognosis and diagnosis of a variety of diseases.
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Description

field of invention

[0001] This application is in the field of functional peptides and more specifically in the field of controlled protein aggregation. The present invention discloses molecules of peptide structure as defined in the claims, and methods of using such molecules in therapeutic and diagnostic applications, as well as other applications such as in the field of agricultural biology (agbio) and industrial biotechnology. The molecules of the invention can be used to treat and / or stabilize infections such as bacterial, fungal and viral diseases, as well as non-infectious human and veterinary diseases. The molecules of the invention can also be used to detect protein biomarkers and in the prognosis and diagnosis of various diseases. Background technique

[0002] Protein aggregation results from protein misfolding and subsequent aggregation in insoluble aggregates. Protein aggregation is essentially a self-association process in which many identical protein molecules...

Claims

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