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A technology of dry albendazole ivermectin and albendazole, which is applied in the field of veterinary albendazole and ivermectin, and can solve uneven mixing of ivermectin, low drug efficacy, poisoning, etc. problems, to achieve the effect of eliminating toxic and side effects, improving drug efficacy, and convenient use
Inactive Publication Date: 2014-02-26
SICHUAN DERUNTONG BIOTECH
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[0007] In the prior art, there have also been reports of compounding albendazole and ivermectin into compound preparations, for example, the application number is 200710150563.9 and the application number is 201010242809.7 It has been ...
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[0034] The first step: Stir and mix the ivermectin and sodium carboxymethyl cellulose in the prescription amount, add sodium saccharin after the powder is uniform, and mix again to obtain A powder, which is set aside;
[0035] Step 2: Take the prescribed amount of albendazole and sodium chloride and stir and mix. After the powder is uniform, add sodium citrate and mix evenly again to prepare B powder;
[0036] Step 3: Add the above B powder to A powder according to the same addition method and stir evenly, then add enough soluble starch and continue to stir and mix for 10 minutes. The albendazole ivermectin powder of off-white powder is obtained.
[0044] 2: Preparation method: the same as the method described in Example 1.
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Abstract
The invention relates to a veterinary anthelmintic, and particularly relates to a veterinary albendazole/ivermectin dry suspension with using convenience and significant drug effects. The dry suspension is prepared by steps of stirring 0.1-0.2 part of ivermectin and 2-4 parts of sodium carboxymethylcellulose and mixing, adding 2-4 parts of a flavoring agent after the powder is mixed uniformly, and mixing uniformly again; stirring 5-15 parts of albendazole and 10-20 parts of sodium chloride and mixing, adding 5-10 parts of sodium citrate after the powder is mixed uniformly, and mixing uniformly again; adding the former into the latter through an equivalent increment method, and stirring uniformly; adding the balance of other auxiliary material, and further uniformly stirring and mixing; and subpackaging to obtain the finished product. The other auxiliary material is soluble starch or microcrystalline cellulose. The dry suspension can be proportionally added in an automatic drinker directly for use, thus facilitating all-round dosing in a large-size livestock farm. The dry suspension avoids the toxic and side effect caused by non-uniform feed mixing, and is more convenient to use. The drug effect is remarkably enhanced, and the cost is obviously lowered in comparison with the prior art. The dry suspension has a wide application prospect.
Description
[0001] This application is a divisional application of the invention patent with the application number: 201210145706.8 and the patent name: "veterinary albendazole ivermectin powder". The original application date: May 10, 2012. technical field [0002] The invention relates to a veterinary anthelmintic, and also relates to veterinary albendazole and ivermectin. Background technique [0003] Albendazole, a benzimidazole anti-helminth drug, has broad-spectrum anthelmintic activity, and has a strong killing effect on nematodes, tapeworms, and trematodes in livestock and poultry. Its mechanism of action is to bind to tubulin in worms and prevent it from multimerizing with α-tubulin to form microtubules, thereby affecting cell reproduction processes such as mitosis, protein assembly and energy metabolism in worms, and inhibiting The purpose of parasite growth and reproduction. [0004] Ivermectin has a good killing effect on internal and external parasites, especially arthrop...
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