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Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof

A technology of pulmonary fibrosis and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of idiopathic pulmonary fibrosis, can solve the problem of inability to effectively prevent the development of fibrosis, lack of unified understanding of pulmonary fibrosis syndrome differentiation, It can not reduce the mortality rate of tissue fibrosis and other problems, and achieve the effect of reducing rale score, reducing disease pain and prolonging survival time

Active Publication Date: 2014-02-26
HEILONGJIANG ACAD OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drugs currently widely used to treat various fibrosis, including various specific cytokine antagonists involved in the occurrence of fibrosis, and therapeutic monoclonal antibodies, cannot effectively prevent the development of fibrosis, let alone reduce tissue fibrosis. disease mortality
[0006] So far, although there is no unified understanding of the syndrome differentiation and classification of pulmonary fibrosis in the academic circle of traditional Chinese medicine

Method used

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  • Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof
  • Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof
  • Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0309] Embodiment 1 Granules

[0310] The Chinese medicine composition for the treatment of idiopathic pulmonary fibrosis described in the present embodiment, its formula is as follows:

[0311] 18 parts by weight of salvia miltiorrhiza, 12 parts by weight of flat shell, 9 parts by weight of peach kernel, 9 parts by weight of chuanxiong, 6 parts by weight of earthworm, 12 parts by weight of bellflower, 18 parts by weight of astragalus, 12 parts by weight of codonopsis, 9 parts by weight of psoralen, wheat Winter 12 parts by weight, schisandra 9 parts by weight.

[0312] The above-mentioned Chinese medicine composition is prepared into granules according to the following steps:

[0313] (1) Pulverize the crude drug of Pingbei according to the above-mentioned selected weight into fine powder, and pass through a 120-mesh sieve for later use;

[0314] (2) Take Danshen, peach kernel, Chuanxiong, Dilong, Platycodon grandiflorum, Astragalus, Codonopsis, psoraleae, Ophiopogon japoni...

Embodiment 2

[0316] Embodiment 2 capsules

[0317] The Chinese medicine composition for the treatment of idiopathic pulmonary fibrosis described in the present embodiment, its formula is as follows:

[0318] Danshen 16g, Pingbei 14g, peach kernel 7g, Chuanxiong 11g, earthworm 4g, bellflower 14g, astragalus 16g, codonopsis 14g, psoralen 7g, radix 14g, schisandra 7g.

[0319] The above-mentioned Chinese medicine composition is prepared into capsules according to the following steps:

[0320] (1) Pulverize the crude drug of Pingbei according to the above-mentioned selected weight into fine powder, and pass through a 120-mesh sieve for later use;

[0321] (2) According to the selected weight, mix Danshen, peach kernel, Chuanxiong, earthworm, platycodon, astragalus, codonopsis, psoralen, radix radix and schisandra, add water to decoct twice, and add water 8 times the weight of the medicine for the first time , decoct for 2 hours, add 10 times the amount of water for the second time, decoct fo...

Embodiment 3

[0322] Embodiment 3 Concentrated pills

[0323] The Chinese medicine composition for the treatment of idiopathic pulmonary fibrosis described in the present embodiment, its formula is as follows:

[0324] Salvia miltiorrhiza 20g, flat shellfish 10g, peach kernel 11g, chuanxiong 7g, earthworm 8g, bellflower 10g, astragalus 20g, codonopsis 10g, psoralen 11g, radix 10g, schisandra 11g.

[0325] The above-mentioned Chinese medicine composition is prepared into concentrated pills according to the following steps:

[0326] (1) Take flat shells according to the selected parts by weight, grind them into fine powder, and pass through a 120-mesh sieve for later use;

[0327] (2) Take Danshen, peach kernel, Chuanxiong, earthworm, platycodon, astragalus, codonopsis, psoralen, radix and schisandra according to the selected weight, add water to decoct twice, and add 12 times the drug weight for the first time Water, decoct for 1.5 hours, add 6 times the amount of water for the second time...

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Abstract

The invention provides a traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and a preparation method thereof. The traditional Chinese medicine composition comprises, by weight, 13-23 parts of red sage root, 7-17 parts of bulb of fritillary, 4-14 parts of peach seed, 4-14 parts of ligusticum wallichii, 1-11 parts of lumbricus, 7-17 parts of balloonflower root, 13-23 parts of milkvetch root, 7-17 parts of pilose asiabell root, 4-14 parts of fructus psoraleae, 7-17 parts of tuber of dwarf lilyturf and 4-14 parts of Chinese magnoliavine fruit. The traditional Chinese medicine composition effectively treats idiopathic pulmonary fibrosis, is safe and stable, obviously improves human body immunity, especially improve respiratory system immunity, has effects of promoting blood circulation to remove blood stasis, reducing phlegm and dredging collaterals, and tonifying lung, spleen and kidney, relieves disease pain and prolongs a human life.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and a preparation method thereof. Background technique [0002] Idiopathic pulmonary fibrosis refers to a type of idiopathic interstitial pneumonia that pathologically manifests as usual interstitial pneumonia, and is the most common in idiopathic interstitial pneumonia, accounting for 47%-71%. The lesions are limited to the lungs, causing diffuse pulmonary fibrosis, clinically manifested as progressive exertional shortness of breath, restrictive ventilatory dysfunction with reduced diffusing capacity, hypoxemia, and diffuse lesions in both lungs on imaging. The course of the disease usually progresses slowly, with gradual loss of alveolar-capillary functional units, and eventually develops into diffuse pulmonary fibrosis and honeycombing, leading to respiratory failure an...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P11/00A61K35/56A61K35/62
Inventor 江柏华张碧海
Owner HEILONGJIANG ACAD OF TCM
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