Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof

A technology of pulmonary fibrosis and composition, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of idiopathic pulmonary fibrosis, can solve the problem of inability to effectively prevent the development of fibrosis, lack of unified understanding of pulmonary fibrosis syndrome differentiation, It can not reduce the mortality rate of tissue fibrosis and other problems, and achieve the effect of reducing rale score, reducing disease pain and prolonging survival time

Active Publication Date: 2014-02-26
HEILONGJIANG ACAD OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drugs currently widely used to treat various fibrosis, including various specific cytokine antagonists involved in the occurrence of fibrosis, and therapeutic monoclonal antibodies, cannot effectively prevent the development of fib

Method used

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  • Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof
  • Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof
  • Traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and preparation method thereof

Examples

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Example Embodiment

[0309] Example 1 Granules

[0310] The traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis described in this embodiment has the following formula:

[0311] 18 parts by weight of Danshen, 12 parts by weight of flat shells, 9 parts by weight of peach kernel, 9 parts by weight of Chuanxiong, 6 parts by weight of earthworm, 12 parts by weight of platycodon, 18 parts by weight of astragalus, 12 parts by weight of Codonopsis, 9 parts by weight of psoralen, wheat 12 parts by weight of winter and 9 parts by weight of schisandra.

[0312] The above-mentioned traditional Chinese medicine composition is prepared into a granular preparation according to the following steps:

[0313] (1) According to the above-mentioned selected weight of the raw material medicine of Pingbei, pulverize into fine powder and pass through a 120-mesh sieve for use;

[0314] (2) Mix Danshen, peach kernels, Chuanxiong, Dilong, platycodon, astragalus, codonopsis, psoralen, Ophiopogon japoni...

Example Embodiment

[0316] Example 2 Capsules

[0317] The traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis described in this embodiment has the following formula:

[0318] Salvia 16g, Pingbei 14g, Peach kernel 7g, Chuanxiong 11g, Dilong 4g, Platycodon 14g, Astragalus 16g, Codonopsis 14g, Psoralen 7g, Ophiopogon 14g, Schisandra 7g.

[0319] The above-mentioned Chinese medicine composition is prepared into capsules according to the following steps:

[0320] (1) According to the above-mentioned selected weight of the raw material medicine of Pingbei, pulverize into fine powder and pass through a 120-mesh sieve for use;

[0321] (2) Mix Danshen, peach kernels, Chuanxiong, Dilong, platycodon, astragalus, codonopsis, psoralen, Ophiopogon japonicus and schisandra according to the selected weight, add water to decoct twice, add 8 times the weight of the medicine for the first time , Decoct for 2 hours, add 10 times the amount of water for the second time, decoct for 1 hour, fil...

Example Embodiment

[0322] Example 3 concentrated pills

[0323] The traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis described in this embodiment has the following formula:

[0324] Salvia 20g, Pingbei 10g, Peach kernel 11g, Chuanxiong 7g, Dilong 8g, Platycodon grandiflorum 10g, Astragalus 20g, Codonopsis 10g, Psoralen 11g, Ophiopogon 10g, Schisandra 11g.

[0325] The above-mentioned traditional Chinese medicine composition is prepared into concentrated pills according to the following steps:

[0326] (1) Take flat scallops according to the selected parts by weight, crush them into fine powder, and pass through a 120-mesh sieve for use;

[0327] (2) According to the selected weight, take Danshen, peach kernel, Chuanxiong, Dilong, platycodon, astragalus, Codonopsis, psoralen, Ophiopogon japonicus, and schisandra and mix it with water and decoct twice. The first time is 12 times the weight of the medicine. Decoction with water for 1.5 hours, add 6 times the amount of wate...

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Abstract

The invention provides a traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and a preparation method thereof. The traditional Chinese medicine composition comprises, by weight, 13-23 parts of red sage root, 7-17 parts of bulb of fritillary, 4-14 parts of peach seed, 4-14 parts of ligusticum wallichii, 1-11 parts of lumbricus, 7-17 parts of balloonflower root, 13-23 parts of milkvetch root, 7-17 parts of pilose asiabell root, 4-14 parts of fructus psoraleae, 7-17 parts of tuber of dwarf lilyturf and 4-14 parts of Chinese magnoliavine fruit. The traditional Chinese medicine composition effectively treats idiopathic pulmonary fibrosis, is safe and stable, obviously improves human body immunity, especially improve respiratory system immunity, has effects of promoting blood circulation to remove blood stasis, reducing phlegm and dredging collaterals, and tonifying lung, spleen and kidney, relieves disease pain and prolongs a human life.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and in particular relates to a traditional Chinese medicine composition for treating idiopathic pulmonary fibrosis and a preparation method thereof. Background technique [0002] Idiopathic pulmonary fibrosis refers to a type of idiopathic interstitial pneumonia that pathologically manifests as usual interstitial pneumonia, and is the most common in idiopathic interstitial pneumonia, accounting for 47%-71%. The lesions are limited to the lungs, causing diffuse pulmonary fibrosis, clinically manifested as progressive exertional shortness of breath, restrictive ventilatory dysfunction with reduced diffusing capacity, hypoxemia, and diffuse lesions in both lungs on imaging. The course of the disease usually progresses slowly, with gradual loss of alveolar-capillary functional units, and eventually develops into diffuse pulmonary fibrosis and honeycombing, leading to respiratory failure an...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P11/00A61K35/56A61K35/62
Inventor 江柏华张碧海
Owner HEILONGJIANG ACAD OF TCM
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