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Lower extremity arteriosclerosis-like vascular model and preparation method thereof

An arteriosclerosis and vascular model technology, applied in the field of vascular model, can solve problems such as changes, and achieve the effect of reducing radiation dose, reducing radiation dose and radiation carcinogenic risk, and ensuring medical safety.

Inactive Publication Date: 2016-04-27
TIANJIN HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition, in the process of timing selection, method selection, natural history and postoperative follow-up of different treatment options for ASO, CTA will be applied many times, so X-ray radiation dose must be considered
Reducing the tube voltage is an important method to reduce the radiation dose, but will the CT value of the structure of interest change after the tube voltage changes? Especially for some complex structures, such as atherosclerosis, the lesion contains non-calcified plaque, calcified plaque, contrast agent and other substances with greatly different tissue densities. Under the condition of tube voltage changes, these Whether the CT value of the material will change, and whether the complex structure around the material will affect the measurement of the CT value of the region of interest, these factors directly affect the safety of the patient and the outcome of the treatment. The current literature on reducing the radiation dose of CTAX rays The reports mainly focus on coronary artery lesions, and there are few domestic and foreign research reports on reducing the CTAX radiation dose of lower extremity arteries

Method used

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  • Lower extremity arteriosclerosis-like vascular model and preparation method thereof
  • Lower extremity arteriosclerosis-like vascular model and preparation method thereof
  • Lower extremity arteriosclerosis-like vascular model and preparation method thereof

Examples

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preparation example Construction

[0027] A method for preparing a lower extremity arteriosclerosis vascular model, characterized in that:

[0028] (1) Use medical latex tube 1 with an inner diameter of 4-40mm, an outer diameter of 5-50mm, and a length of 100-1000mm to simulate human blood vessels, and use medical silica gel and bio-glue to make irregular blocks to obtain bio-glue blocks 2, silica gel Block 3 is used to simulate the calcified plaque structure and non-calcified plaque structure attached to the blood vessel wall respectively;

[0029] (2) Place the silica gel block 3 and the bio-glue block 2 on the top, middle and bottom of the latex tube 1 respectively, and fix the models of the silica gel block 3 and the bio-glue block 2 inside and outside the tube wall of the latex tube 1;

[0030] (3) Inject iodine contrast agent 4 with a concentration of 14 mgI / ml into the prepared model until the iodine contrast agent 4 fills the entire model, and the air in the model is discharged, and latex plugs of the s...

Embodiment

[0033] Example: such as figure 1 , figure 2 As shown, use latex blocks with different tissue densities (ρ≤0.9374g / cm 3 ), biological rubber block 2 (ρ≤0.9611g / cm 3 ), medical silica gel block 3 (ρ≥1.163g / cm 3 ) and iodine contrast agent 4 with a concentration of 14mgI / ml (diluted from Omnipaque, 350mgI / ml) to prepare the arteriosclerotic vascular model. A medical latex tube 1 with an inner diameter of 4-40mm, an outer diameter of 5-50mm, and a length of 100-1000mm is used to simulate human blood vessels. Medical silica gel and biological glue are used to make irregular blocks, respectively simulating calcified and non-calcified plaques attached to the blood vessel wall. The upper, middle and lower places of the latex tube 1 were selected to place the silica gel block 3 and the bio-glue block 2 respectively, the model of the silica gel block 3 was fixed outside the tube wall, and the model of the bio-glue block 2 was fixed inside the tube wall. Inject iodine contrast agen...

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Abstract

The invention belongs to the technical field of blood vessel models, especially to a lower-limb arteriosclerosis blood vessel simulating model and a preparation method thereof. Different structures of a lower-limb arteriosclerosis blood vessel are respectively simulated by different densities of substances, wherein a vessel wall structure is simulated by an emulsion tube, non-calcified plaque is simulated by biogel blocks, calcified plaque is simulated by silica gel blocks, and blood containing an iodine contrast agent is simulated by the iodine contrast agent; the biogel blocks and the silica gel blocks are fixed on the emulsion tube, and the inside of the emulsion tube is filled with the iodine contrast agent; air in the model is exhausted, and the two ends of the model are respectively sealed by emulsion plugs whose material is the same with that of the emulsion tube. The lower-limb arteriosclerosis blood vessel simulating model and the preparation method thereof have the advantages that the lower-limb arteriosclerosis blood vessel can be simulated in CT angiography examination, influence of different tube voltages and peripheral structures on CT values can be simulated via the model, the radiation dose of X rays is reduced to the minimum under the condition that diagnosis is not influenced, medical safety is ensured, the radiation dose received by a patient is reduced, and the risk of radiation carcinogen is reduced.

Description

technical field [0001] The invention belongs to the technical field of blood vessel models, and in particular relates to a lower extremity arteriosclerosis blood vessel model and a preparation method thereof. Background technique [0002] With the continuous development of computer hardware and software research and development technology, high-end CT can complete a wide range of scans in a short period of time, with clearer images and more intuitive display of lesions. etc. have played an increasingly important role. Therefore, CT has increasingly become an important tool for disease diagnosis, and clinicians rely more and more on CT. According to statistics, during the ten years from 1997 to 2007, the annual use of CT in the United States increased by three times, 14% of emergency patients underwent CT examination, and nearly 2% of cancer patients may be caused by radiation from CT scanning. CT examination has become a radiation source that cannot be ignored. [0003] C...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G09B23/28
Inventor 万业达张越傅菲何岸苇
Owner TIANJIN HOSPITAL
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