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An ion measuring device

A measuring device and ion technology, which is applied to the parts of the particle separator tube, sample introduction/extraction, etc., can solve the problems of unmaintainable and purposeful detection of ion transmission efficiency, etc., to achieve small measurement errors and improve reliability performance and maintainability, ease of measurement

Active Publication Date: 2016-04-27
杭州谱聚医疗科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

This solution can realize the estimation of ion transmission efficiency, but for the case where there are many stages of ion lenses and transmission rods in an ion optical system, the entire ion optical system is a black box, and it is impossible to locate the ion loss on which stage , it is impossible to purposely detect the ion transmission efficiency of each level, and it is impossible to timely maintain the level with a large ion loss

Method used

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  • An ion measuring device
  • An ion measuring device
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Examples

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Embodiment 1

[0031] see figure 1 , a kind of ion measurement device, comprises ion optics system 1, isolated pulse power supply 2, control unit 3 and processing unit 4; Described ion optics system 1 comprises ion lens; Described control unit 3 and processing unit 4 and described isolation pulse connected to the power supply;

[0032] The control unit 3 controls the isolated pulse power supply 2 to provide voltage to the ion lens, ions impact on the ion lens to form an ion current, and the ion current is output from the relative ground terminal of the secondary side of the pulse isolation power supply;

[0033] The ion current output from the opposite ground terminal of the pulse isolation power supply 2 is received by the processing unit 4 and calculated by the processing unit 4 to obtain the corresponding ion transmission quantity. Preferably, the control unit 3 can obtain the corresponding ion transmission efficiency according to the ion transmission quantity.

[0034] Preferably, the ...

Embodiment 2

[0037] see figure 2 , a kind of ion measuring device, different from the ion measuring device described in embodiment 1 is:

[0038] The processing unit 40 includes an operational amplifier circuit 401 and an analog-to-digital converter 402 , and the opposite ground terminal of the secondary side of the isolated pulse power supply 2 is connected to the input terminal of the operational amplifier circuit 401 .

[0039] Preferably, the operational amplifier circuit includes a logarithmic amplifier circuit.

[0040] The analog-to-digital converter 402 in this embodiment is a 24-bit ADC processor.

[0041] Since the input terminal of the operational amplifier circuit is at the same potential as the ground terminal, the relative ground terminal of the secondary side of the isolated pulse power supply is connected to the input terminal of the operational amplifier circuit, which is equivalent to realizing the relative ground terminal of the secondary side of the isolated pulse pow...

Embodiment 3

[0045] see image 3 , a kind of ion measuring device, different from the ion measuring device described in embodiment 2 is

[0046] The processing unit 41 also includes a filtering circuit 403 . The filter circuit is placed between the operational amplifier circuit 401 and the analog-to-digital converter 402 . In order to prevent the interference of the external leakage current, the signal input line of the filter circuit 403 is double shielded and directly connected to the input pin of the operational amplifier circuit.

[0047] In the case that the radio frequency voltage amplitude is high, thereby causing radiation interference or conduction interference to the circuit, the ion measurement device can effectively remove the interference of the radio frequency power supply inside the vacuum cavity in the ion optical system, and at the same time prevent the interference of external leakage current, so that the ion The measuring device has strong anti-interference ability.

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Abstract

The invention relates to an ion measuring device. The ion measuring device comprises an ion optical system, wherein the ion optical system comprises an ion lens, and the ion measuring device is characterized by also comprising an isolation pulse power supply which is connected with the ion lens as well as a control unit and a processing unit, which are connected with the isolation pulse power supply; the control unit controls the isolation pulse power supply to supply voltage to the ion lens, and the processing unit receives and calculates ions transmitted by the ion lens. The ion measuring device has the advantages of good measuring real-time property, small measuring error, low cost, simplicity and convenience in measurement and the like.

Description

technical field [0001] The invention relates to an ion measuring device, in particular to an ion measuring device capable of real-time on-line detection. Background technique [0002] When performing tandem mass spectrometry (MS / MS), ions in the ion optical system enter the transmission channel and are transported by airflow and electric field. The ion optics system includes ion lenses and transfer rods. During the transmission of ions in the transmission channel, the ions collide with each other to change the ion transmission rate and transmission direction; if the ions hit the transmission channel wall, such as the ion lens, they will return to the ion source generator through the ground terminal, and will not Continue to transmit, thereby affecting the ion transmission efficiency. [0003] The ion transmission efficiency reflects the sensitivity of the instrument, so it is necessary to design a device that can accurately measure the ion intensity, so as to obtain the io...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): H01J49/04
Inventor 张建李纲邓丰涛李文
Owner 杭州谱聚医疗科技有限公司
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