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Cleaning liquid for coagulometer

A technology of coagulation analyzer and cleaning solution, applied in the field of cleaning solution, can solve the problems of poor use effect, negative influence of instrument counting part and pipeline, etc., and achieve the effects of good affinity, easy storage and safe operation

Active Publication Date: 2014-05-07
SHENZHEN PREVENTION & TREATMENT CENT FOR OCCUPATIONAL DISEASES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Even though domestic manufacturers currently produce alternative cleaning fluids, the effect is not good, mainly because crystallization is easy to occur after opening, which has a huge negative impact on the counting part of the instrument and pipelines

Method used

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  • Cleaning liquid for coagulometer
  • Cleaning liquid for coagulometer
  • Cleaning liquid for coagulometer

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1, the preparation of the cleaning liquid of coagulation analyzer

[0035] 1. Buffer

[0036] Accurately weigh 6.38g of sodium chloride, 1.00g of boric acid, 0.20g of sodium tetraborate, EDTA-K 2 0.20g, dissolve the above solute in deionized water (pH value = 7.0), and make up to 1L with deionized water; after fully mixing and dissolving, use a 0.22 micron microporous filter membrane for negative pressure filtration, and collect the filtrate as the buffer .

[0037] 2. Cleaning fluid

[0038] Measure 180ml of the above buffer solution, add 20ml of 10% analytically pure sodium hypochlorite (mass percentage), then add 1mg of sodium hydroxide, 0.6g of alkaline protease (Beijing Aoboxing Biotechnology Co., Ltd., catalog number 01-132, 200000u / g), adjust the pH value to 12.40 with a standard buffer solution of potassium dihydrogen phosphate and disodium hydrogen phosphate at pH 6.86, and use a 0.22 micron microporous filter membrane for negative pressure filtr...

Embodiment 2

[0041] Embodiment 2, the application of cleaning solution

[0042] The cleaning solution effect evaluation of above-mentioned development is as follows:

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Abstract

The invention discloses a cleaning liquid for a coagulometer. The cleaning liquid comprises the following components of sodium chloride, boric acid, sodium borate, EDTA (ethylene diamine tetraacetic acid)-K2, sodium hypochlorite, sodium hydroxide, alkaline protease and water according to the proportion of 0.574g:0.09g:0.018g: 0.018g:1.0g:0.001g:0.1g. Experiments prove that the cleaning liquid for the coagulometer has colorless and transparent appearance and stable physical and chemical indexes, and has no phenomena of crystallization, precipitation and turbidity after half-year use, all the physical and chemical indexes are stable; the cleaning liquid has low cost, is equivalent to or superior to an original cleaning liquid CA CLEAN I in physical and chemical indexes, stability, cleaning effect and actual use effect, and has good stability, long period of validity and good cleaning effect, and the formula reagent is easy to purchase.

Description

technical field [0001] The invention relates to a cleaning solution, in particular to a cleaning solution for a blood coagulation analyzer. Background technique [0002] Cleaning solution is an important reagent in the daily use and maintenance of the coagulation analyzer. It can maintain the stable performance of the instrument and prolong the service life of the instrument by cleaning the counting pipeline, counting pool, colorimetric pool and jewel hole of the coagulation analyzer. Under the action of the cleaning solution, blood clots and other dirt are fully dissolved and washed by the diluent, so as to achieve the purpose of cleaning the counting pipeline system of the coagulation analyzer. [0003] The SYSMEX CA-500 coagulation analyzer is widely used in China, and the daily consumption of cleaning fluid is relatively large. The original cleaning fluid used is CA CLEAN I, which is expensive and completely dependent on imports. Domestic scholars have developed more al...

Claims

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Application Information

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IPC IPC(8): C11D7/60C11D7/10C11D7/42C11D7/08C11D7/32C11D7/06
Inventor 王佃鹏汤海燕罗斌张志敏邓丽丹李培茂高燕华张艳芳惠长野
Owner SHENZHEN PREVENTION & TREATMENT CENT FOR OCCUPATIONAL DISEASES
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