Application of artesunate and ulinastatin in combined treatment of pancreatitis
A technology of artesunate and ulinastatin, which is applied in the direction of medical preparations containing active ingredients, drug combinations, peptide/protein components, etc., to achieve the effects of broadening applications, reducing side effects, and reducing dosage
Inactive Publication Date: 2014-05-14
ARMY MEDICAL UNIV
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However, there is no report on the combination of artesun
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[0026] The present invention will be further described below in conjunction with examples, but the examples are only used to understand the present invention and not to limit the scope of the present invention.
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The invention relates to an application of existing antimalarial artesunate and ulinastatin in combined treatment of pancreatitis. The combination of artesunate and ulinastatin generates a synergistic effect, enhances the therapeutic effect of ulinastatin, and reduces dosage of ulinastatin. The invention provides a new treatment use of antimalarial artesunate.
Description
technical field [0001] The invention belongs to the field of medicine and pharmaceutical preparations, and in particular relates to the use of artesunate and ulinastatin in combined treatment of acute pancreatitis. Background technique [0002] Acute pancreatitis (Acute Pancreatitis, AP) is a common clinical disease with a high incidence. Due to the acute onset of acute pancreatitis, the disease develops quickly and complicatedly: from the initial local lesion of pancreatic tissue, it can rapidly develop into systemic inflammatory response syndrome (SIRS), sepsis, septic shock and even multi-organ Functional failure, even death, is very difficult to treat. Although comprehensive therapy is used for clinical treatment, the effect is not satisfactory, and the overall mortality rate is still as high as 5% to 13.6%. [0003] The treatment of AP is mainly based on comprehensive medical treatment, and only 2% of patients finally receive surgical treatment. The medical treatment ...
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Login to view more IPC IPC(8): A61K38/17A61P1/18A61K31/357
Inventor 周红岑彦艳李小丽郑江覃容欣
Owner ARMY MEDICAL UNIV
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