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Application of proanthocyanidins in preparing diet food or drug

A technology of proanthocyanidins and diet food, applied in the application field of traditional Chinese medicine, can solve the problem that the weight loss effect of proanthocyanidins is not reported in patent literature, etc., and achieve the effects of protecting eyesight, protecting blood circulation, and having no toxic and side effects.

Inactive Publication Date: 2014-06-04
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, the research on the use of proanthocyanidins is relatively in-depth, but there is no patent literature report on the weight loss effect of proanthocyanidins

Method used

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  • Application of proanthocyanidins in preparing diet food or drug
  • Application of proanthocyanidins in preparing diet food or drug
  • Application of proanthocyanidins in preparing diet food or drug

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Proanthocyanidin beverage (according to mass fraction):

[0034] Proanthocyanidins 0.2%, citric acid 0.1%, honey 4.35%, aspartame 1.5%, vanilla essence 0.05%, water 93.8%.

[0035] According to the mass fraction of the above formula, 20 grams of proanthocyanidins, 1 gram of citric acid, 435 grams of honey, 150 grams of aspartame, 5 grams of vanilla essence, and 9380 grams of water are mixed evenly, boiled, and aseptically filled into beverage bottles. Each bottle is 200ml, and the content of proanthocyanidins is 400mg / bottle.

[0036] Dosage for adults: Take 1 bottle per day, once a day.

Embodiment 2

[0038] Proanthocyanidin capsules (according to mass fraction):

[0039] Proanthocyanidins 30%, gelatin 18%, casein phosphopeptide 27.5%, magnesium stearate 1.5%, D-mannitol 23%.

[0040] According to the mass fraction of the above formula, 30 g of proanthocyanidin and 18 g of gelatin were dissolved in 150 g of water, and spray-dried to prepare proanthocyanidin microcapsule particles. 27.5 grams of casein phosphopeptides, 23 grams of D-mannitol, 1.5 grams of magnesium stearate and microcapsules are put into a multi-position mixer and fully mixed to make wet granules, passed through a 20-mesh sieve, dried, and granulated. Capsules are made by subpackaging with a capsule filling machine. 250mg / capsule, proanthocyanidin content 75mg / capsule.

[0041] Dosage for adults: Take 2 capsules 2 times a day.

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Abstract

The invention discloses an application of proanthocyanidins in preparing diet food or drug, and discloses an application of a drug composition with proanthocyanidins as an active component and pharmaceutically acceptable additives in preparing the diet food or drug. Mice experiments demonstrate that proanthocyanidins has obvious reduction effects for growth rate of mice body weight, food utilization rate and body fat and presents a dose-dependent relationship, can effectively reduce blood glucose level and serum cholesterol level of the mice, and can increase serum free fatty acid level and oxidation resistant level. Novel medical application and novel application field are developed for proanthocyanidins. Experiments show that the concentration of proanthocyanidins required for treating obesity is relatively low; proanthocyanidins has no side or toxic effect and has the functions of protecting human body blood circulation, enhancing immunity and protecting eyesight, thereby guaranteeing effectiveness of weight reduction and playing a promotion effect for body health.

Description

technical field [0001] The invention relates to the technical field of application of traditional Chinese medicines, in particular to the application of proanthocyanidins in the preparation of diet food or medicine. Background technique [0002] Obesity refers to the disorder of the body's control of body fat and energy metabolism balance mechanism, resulting in excessive accumulation or abnormal distribution of body fat, resulting in increased body mass. It is a multifactorial chronic metabolic disease. In recent years, both developed countries and developing countries undergoing economic reforms and changes in nutrition patterns are facing the problem of accelerated development of obesity, which brings huge medical costs and social burdens. The World Health Organization (WHO) has listed obesity as one of the four major medical and social problems in the world today, and has confirmed it as the chronic disease with the highest prevalence among adults in the world. [0003]...

Claims

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Application Information

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IPC IPC(8): A23L1/30A61K31/353A61P3/04A23L33/105
CPCA23L33/20A23V2002/00A61K9/0095A61K9/4866A61K31/353A23V2250/2104A23V2200/332
Inventor 陈卫苏鸿铭郑晓冬
Owner ZHEJIANG UNIV
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