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Traditional Chinese medicine compound preparation, preparation method and medicine box thereof

A technology for compound preparations and traditional Chinese medicines, which is used in pharmaceutical formulations, antiviral agents, drug combinations, etc.

Active Publication Date: 2014-08-06
SHANGHAI INST OF PHARMA IND +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The effect of traditional Chinese medicine on the prevention and treatment of respiratory virus infection has been continuously confirmed

Method used

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  • Traditional Chinese medicine compound preparation, preparation method and medicine box thereof
  • Traditional Chinese medicine compound preparation, preparation method and medicine box thereof
  • Traditional Chinese medicine compound preparation, preparation method and medicine box thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Take the crude drug by weighing the following proportioning (compound recipe F1):

[0082] Shanyinhua 1Ig Chrysanthemum 10g Forsythia 6.5g Chenpi 2.5g Hawthorn 5g Bitter almond 5g

[0083] (1) Take mountain silver flower, chrysanthemum, forsythia, tangerine peel, pulverize, add 8 times the amount of water, use steam distillation to collect volatile oil and aromatic water twice, combine the volatile oil and aromatic water collected twice, and set aside; The raw materials were boiled twice, each time for 30 minutes, filtered, the filtrates were combined twice, concentrated under reduced pressure, dried to obtain extract I, and set aside;

[0084] (2) Take hawthorn and bitter almonds, crush them, add 5 times the amount of water, decoct twice for 30 minutes each time, filter, combine the filtrates twice, concentrate under reduced pressure, dry to obtain extract II, and set aside;

[0085] (3) Extract I is mixed with Extract II to obtain the total extract, which is set asid...

Embodiment 2

[0088] Take the crude drug by weighing the following proportioning (compound recipe F2):

[0089] Shanyinhua 12g Chrysanthemum 8g Forsythia 5g Chenpi 4g Hawthorn 6g Bitter almond 5g

[0090] Steps (1), (2) and (3) are the same as in Example 1, and step (4) is to add an appropriate amount of sucrose and dextrin to the total extract prepared in step (3), mix well, make granules, dry, spray Add the volatile oil and aromatic water prepared in the step (1), and then prepare the traditional Chinese medicine compound capsule of the present invention according to a conventional process.

Embodiment 3

[0092] Take the crude drug by weighing the following proportioning (compound recipe F3):

[0093] Shanyinhua 10g Chrysanthemum 11g Forsythia 7g Chenpi 2g Hawthorn 4g Bitter almond 6g

[0094](1) Take mountain silver flower, chrysanthemum, forsythia, tangerine peel, pulverize, use supercritical carbon dioxide to extract volatile oil and aromatic water, the conditions are: extraction temperature is 50°C, pressure is 32Mpa, analysis temperature is 60°C, pressure is 6Mpa, The average flow rate is 12Skg / h, extract for 3 hours, get volatile oil and aromatic water, use β-cyclodextrin for clathrate, dry, get volatile oil clathrate; boil the above raw materials twice, each time for 40min, filter and combine Twice the filtrate was concentrated under reduced pressure and dried to obtain extract I for subsequent use;

[0095] (2) Take hawthorn and bitter almonds, grind them, add 10 times the amount of water, decoct twice for 1 hour each time, filter, combine the filtrates twice, concentr...

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Abstract

The invention relates to the field of pharmacy, and especially relates to a traditional Chinese medicine compound for treating acute respiratory virus infection, a preparation method and medicine box thereof. The traditional Chinese medicine compound preparation is composed of the following traditional Chinese herbals in parts by weight: 8 to 12 parts of flos lonicerae, 8 to 12 parts of chrysanthemum, 5 to 8 parts of fructus forsythiae, 2 to 4 parts of dried orange peel, 4 to 6 parts of haw, and 4 to 6 parts of bitter almond. The preparation method comprises the following steps: step one, extracting flos lonicerae, chrysanthemum, fructus forsythiae, and dried orange peel through a water steam distillation method or a supercritical extraction method so as to obtain volatile oil and aromatic water, saving the volatile oil and aromatic water for later use; boiling the raw materials mentioned above in water, filtering, vacuum-condensing the filtrate, and drying so as to obtain an extract I; step two, boiling haw and bitter almond in water, filtering, vacuum-condensing the filtrate, and drying so as to obtain an extract II; step three, mixing the extract I and the extract II so as to obtain a general extract; step four, mixing the general extract with the volatile oil and aromatic water obtained in the step one and medicinal auxiliary materials, and finally making the mixture into medicinal dosage forms. The traditional Chinese medicine compound preparation can be used to treat acute respiratory virus infection.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a compound preparation of traditional Chinese medicines, a preparation method thereof and a medicine box. Background technique [0002] Acute respiratory infection is the most common multiple disease in humans, and its clinical symptoms are fever, headache, cough and so on. Modern medical research has confirmed that: 90-95% of acute respiratory infections are caused by viruses, mainly influenza virus, parainfluenza virus, respiratory syncytial virus, coronavirus, adenovirus, rhinovirus, Coxsackie virus, etc. Because most respiratory viruses are highly contagious and can be transmitted by droplets with a short incubation period, they are very easy to be popular in winter and spring. As far as the site of its pathogenesis is concerned, clinically the common cold and the common cold are mostly acute upper respiratory tract infections, and the condition is relatively mil...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P11/00A61P31/12A61P31/16
Inventor 华茉莉徐云辉许玉张念黄浩
Owner SHANGHAI INST OF PHARMA IND
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