Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Colon-cancer-resistant composition and application thereof

A technology of colon cancer and composition, which is applied in the field of anti-colon cancer composition, can solve the problem that the pathogenesis is not completely clear, and achieve high-efficiency anti-cancer effect and good anti-cancer effect

Inactive Publication Date: 2014-08-27
金鑫
View PDF0 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, its pathogenesis is not completely clear, mainly related to environmental factors and genetic factors

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Colon-cancer-resistant composition and application thereof
  • Colon-cancer-resistant composition and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The traditional Chinese medicine composition is composed of the following raw materials according to the weight ratio: 150 grams of ginseng, 45 grams of Huaijiao, 90 grams of vine pear root, and 110 grams of fig.

[0022] The ginseng raw material is pulverized into 20-40 meshes, wherein the ginseng is fresh ginseng, which is wetted with 50% by weight of the ginseng raw material, and sprayed with 5% by weight of the ginseng raw material Rhizopus oryzae bacterium liquid. Oxygen fermentation for 24 hours to obtain biotransformed ginseng.

[0023] The preparation method is as follows: mix the above-mentioned raw materials according to the corresponding weight ratio, first wash and remove impurities with clean water, then soak it in warm water of 50°C for 1 hour, then add water 5 times the weight of the raw materials, and heat at 75°C Extracted 3 times, cooled and filtered, concentrated below 65°C to form a liquid extract with the same quality as the raw material, and obtain...

Embodiment 2

[0025] The traditional Chinese medicine composition is composed of the following raw materials in proportion by weight: 100 grams of ginseng, 80 grams of sophora japonicus, 40 grams of vine pear root, and 70 grams of fig.

[0026] Ginseng raw material pulverizes 20-40 order, and ginseng is dry ginseng red ginseng mixture, and weight ratio is 1:1, is moistened with the water of 70% weight of ginseng raw material, sprays into the Rhizopus oryzae bacterium liquid of 20% weight of ginseng raw material, at 25 Aerobic fermentation at -30°C for 72 hours to obtain biotransformed ginseng.

[0027] The preparation method is as follows: mix the above-mentioned raw materials according to the corresponding weight ratio, first wash and remove impurities with clean water, and then soak it in warm water of 30°C for 3 hours, then add water three times the weight of the raw materials, and heat at 80°C Extracted 5 times, cooled and filtered, concentrated below 65°C to form a liquid extract with ...

Embodiment 3

[0029] The traditional Chinese medicine composition is composed of the following raw materials according to the weight ratio: 145 grams of ginseng, 65 grams of Huaijiao, 78 grams of vine pear root and 95 grams of fig.

[0030] The ginseng raw material is pulverized into 20-40 meshes, and the ginseng is red ginseng, wetted with 67% of the weight of the ginseng raw material, sprayed with 17% of the weight of the ginseng raw material Rhizopus oryzae bacterium, and aerobically fermented at 25-30°C for 38 hours, to obtain biotransformed ginseng.

[0031] The preparation method is as follows: mix the above-mentioned raw materials according to the corresponding weight ratio, first wash and remove impurities with clean water, and then soak it in warm water of 44°C for 2.5 hours of equal mass, then add water 4 times the weight of the raw materials, at 90 ℃ extraction for 4 times, cooled and filtered, concentrated below 65 ℃ to form a liquid extract with the same quality as the raw mate...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the technical field of pharmaceuticals and particularly relates to a colon-cancer-resistant composition and an application thereof. The colon-cancer-resistant composition disclosed by the invention is characterized by comprising 100-150 parts of ginseng, 45-80 parts of sophora fruits, 40-90 parts of Chinese actinidia roots and 70-110 parts of ficus carica. The colon-cancer-resistant composition has the beneficial effects that experiments prove that 1, drugs respectively have an efficient anti-cancer effect; and 2, the anti-cancer mechanism of the drugs is possible as follows: the transportation function of an L-amino acid transporter 1 is inhibited by effective ingredients in the drugs, so that a favorable anti-cancer effect is achieved.

Description

technical field [0001] The invention belongs to the field of pharmaceutical technology, in particular, the invention relates to an anti-colon cancer composition and its application. Background technique [0002] Colon cancer is the second most prevalent cancer and the third leading cause of cancer death worldwide. At present, its pathogenesis has not been fully clarified, mainly related to environmental factors and genetic factors. Surgical resection is still the only curative method for colon cancer. Because only 70% of colon cancer tumors are resectable, many patients have to receive adjuvant chemotherapy. Therefore, finding anti-colon cancer drugs with better targeting and less toxic side effects has long been the most sought-after goal of researchers in the pharmaceutical field. [0003] L-type amino acid transporter 1 (L-type amino acid transporter 1, LAT1) is a recently discovered cancer cell (including kidney cancer, prostate cancer, bladder cancer, colorectal canc...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/60A61P1/00A61P35/00
Inventor 金鑫
Owner 金鑫
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com