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Myogenic rubine collagen sponge drug as well as preparation method and application thereof

A technology of red collagen sponge and muscle-promoting technology, which is applied in the direction of drug combination, medical formula, plant raw materials, etc., can solve the problem of insufficient antibacterial effect of Shengji Yuhong ointment on the wound surface, and achieve the purpose of increasing bactericidal and anti-inflammatory effects, increasing active ingredients and curative effect , the effect of expanding the scope of application

Active Publication Date: 2014-09-03
JIANGSU PROVINCIAL HOSPITAL OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinical studies have also found that Shengji Yuhong ointment has insufficient antibacterial effect on wounds

Method used

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  • Myogenic rubine collagen sponge drug as well as preparation method and application thereof
  • Myogenic rubine collagen sponge drug as well as preparation method and application thereof
  • Myogenic rubine collagen sponge drug as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0066] Shengji Yuhong Collagen Sponge is made of the following ingredients: Angelica 6g, Licorice 6g, Angelica dahurica 6g, Comfrey 6 parts, Blood 2.4g, Myrobalan 6g, Hollyhock flower 6g, and the carrier is collagen.

[0067] Concrete preparation method comprises the following steps:

[0068] (1) Get the angelica, licorice root, myrobalan and hollyhock flower of formula quantity, soak 30 minutes with 70v / v% ethanol aqueous solution of 8 times of weight, reflux extraction 60 minutes, solid-liquid separation collects filtrate, solid part soaks again with ethanol aqueous solution 30 minutes, reflux extraction for 60 minutes, solid-liquid separation and combined filtrate, recovery of ethanol until there is no alcohol smell to obtain the extract, set aside;

[0069] (2) Take the Angelica dahurica and Comfrey in the formula, grind them into coarse powder, pass through a 20-mesh sieve, moisten with 20mL of ethanol, use 8 times the weight of 70v / v% ethanol aqueous solution as solvent,...

Embodiment 2

[0072] Shengji Yuhong Collagen Sponge is made of the following components: Angelica 5g, Licorice 5g, Angelica dahurica 5g, Comfrey 5 parts, Blood 1g, Myrobalan 5g, Hollyhock flower 5g, and the carrier is collagen.

[0073] The preparation method is the same as in Example 1.

Embodiment 3

[0075] Shengji Yuhong Collagen Sponge is made of the following components: Angelica 10g, Licorice 10g, Angelica dahurica 10g, Comfrey 10 parts, Blood 4g, Myrobalan 10g, Hollyhock flower 10g, and the carrier is collagen.

[0076] The preparation method is the same as in Example 1.

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Abstract

The invention discloses a myogenic rubine collagen sponge drug, which is prepared from the following components in parts by weight: 5-10 parts of angelica sinensis, 5-10 parts of liquorice, 5-10 parts of radix angelicae, 5-10 parts of lithospermum, 1-4 parts of resina draconis, 5-10 parts of fructus chebulae and 5-10 parts of sunset abelmoschus flower, wherein the carrier is collagen. The invention also discloses a preparation method and an application of the myogenic rubine collagen sponge drug. The drug disclosed by the invention is superior to the traditional myogenic rubine paste preparation in the curative effect, does not contain heavy metal mercury, can be implanted into a body to promote repair, and is applied to promoting coalescence of surface painless ulcer, diabetic ulcer and the like, and filling body tissue defects.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and relates to a medicament of Shengji Yuhong collagen sponge, a preparation method and application thereof. Background technique [0002] Chronic body ulcers are often caused by diabetes, pressure sores, hormone application, etc., and are one of the most common clinical difficulties and hot spots. With the trend of population aging, the incidence rate is gradually increasing, which consumes a lot of medical resources and seriously affects the quality of life of patients. According to the research and modern meta-analysis of Johns Hopkins University School of Medicine in the United States, the two key factors affecting healing are wound infection and blood supply, and the standard treatment principle is to actively debride the wound and improve microcirculation; and put forward local external treatment in the future The development of functional excipients is its developmen...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K36/896A61K47/42A61P17/02A61P3/10
Inventor 姚昶吴旭彤卞卫和孙蕾
Owner JIANGSU PROVINCIAL HOSPITAL OF TCM
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