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A kind of traditional Chinese medicine composition with anticancer effect and its preparation method and application

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as high risk, unsatisfactory curative effect, and high cost

Active Publication Date: 2017-03-29
CHENGDU DIAO GROUP TIANFU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most of the cancer treatments are surgical treatment combined with radiotherapy and chemotherapy. However, this method has great trauma to the patient, high risk, and high cost, but the curative effect is not ideal.

Method used

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  • A kind of traditional Chinese medicine composition with anticancer effect and its preparation method and application
  • A kind of traditional Chinese medicine composition with anticancer effect and its preparation method and application
  • A kind of traditional Chinese medicine composition with anticancer effect and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0171] Embodiment 1 oral liquid

[0172] Composition of prescription raw materials: Radix Paeoniae Alba 30g, Angelica sinensis 30g;

[0173] Take the prescribed amount of raw medicine, add water and decoct twice, the first time for 2 hours, the second time for 1.5 hours, combine the decoction, filter, concentrate the filtrate, add ethanol to the concentrated solution until the alcohol content reaches 70%, let stand, Filtrate, recover ethanol from the filtrate until it has no alcohol smell, concentrate to a relative density of 1.15 (60°C), add conventional excipients to make oral liquid.

Embodiment 2

[0174] Example 2 tablet

[0175] Composition of prescription raw materials: Radix Paeoniae Alba 30g, Angelica sinensis 15g;

[0176] Take the raw material medicine of the prescribed amount, add 5 times the amount of 70% ethanol to reflux and extract twice, each time for 1.5 hours; combine the extracts, filter, recover ethanol and concentrate; the concentrated solution is dried under reduced pressure, crushed into fine powder, and added with conventional excipients , mixed; dry compressed granules, tablet, that is.

Embodiment 3

[0177] Embodiment 3 capsules

[0178] Composition of prescription raw materials: Radix Paeoniae Alba 30g, Angelica 60g;

[0179] Take the raw material medicine of the prescribed amount, add 10 times the amount of methanol and ultrasonically extract 3 times, the first time is 40 minutes, the second time and the third time are 20 minutes each, the extracts are combined, filtered, concentrated under reduced pressure; the concentrated solution is dried under reduced pressure, crushed into fine powder powder, add conventional auxiliary materials, and mix well; dry-compressed granules, put into capsules, and obtain.

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PUM

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Abstract

The invention provides a traditional Chinese medicine composition having anticancer effects and a preparing method and uses thereof. The traditional Chinese medicine composition mainly comprises following raw material medicines: white paeony root and Chinese angelica. The preparing method includes: weighing the raw material medicines according to a ratio, and extracting with water or an organic solvent mutually soluble with water; or weighing the raw material medicines according to the ratio and preparing by adoption of a water extraction and alcohol precipitation method, wherein the alcohol precipitation concentration is 50-90. The uses of the composition relate to applications of the composition in preparation of medicines treating cancer especially medicines treating cervical cancer. The composition comprises the white paeony root and the Chinese angelica in a weight ratio of 1:(0.2-4). By compatibility of the white paeony root and the Chinese angelica, the composition has coordinate repression effects for Hela cells and has good anticancer effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition and its preparation method and use, in particular to a traditional Chinese medicine composition with anticancer effect and its preparation method and use, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Cancer is a major disease that threatens human health, and its fatality rate is increasing year by year. Its occurrence and development are complex pathological processes involving multiple factors, multiple gene changes, and multi-stage development. At present, the treatment of cancer mostly adopts surgical treatment combined with radiotherapy and chemotherapy, but this method has great trauma to the patient, high risk, and high cost, but the curative effect is not ideal. Traditional Chinese medicine, as a traditional weapon for disease prevention and treatment in my country, has received more and more attention in cancer treatment with t...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/71A61P35/00
Inventor 姚华王军杜军郭洁李芳
Owner CHENGDU DIAO GROUP TIANFU PHARMA