Application of compound e-jiao slurry in preparation of medicine for preventing or treating Xingjiang haemorrhagic fever

A technology of compound donkey-hide gelatin and hemorrhagic fever, which is applied in the application field of medicine and can solve the problems that there is no positive effect of compound donkey-hide gelatin

Active Publication Date: 2014-10-01
SHAN DONG DONG E E JIAO
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0013] So far, there is no report that compound donkey-hide gelatin has a positive effect in the treatment of Xinjiang hemorrhagic fever.

Method used

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  • Application of compound e-jiao slurry in preparation of medicine for preventing or treating Xingjiang haemorrhagic fever
  • Application of compound e-jiao slurry in preparation of medicine for preventing or treating Xingjiang haemorrhagic fever
  • Application of compound e-jiao slurry in preparation of medicine for preventing or treating Xingjiang haemorrhagic fever

Examples

Experimental program
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Effect test

experiment example 1

[0026] Experimental example 1: Observation on the curative effect of compound donkey-hide gelatin on blood test recovery in patients with hemorrhagic fever in Xinjiang

[0027] 1 General information

[0028] The 42 sera were all collected from XHF suspected patients who visited the Xinjiang Center for Disease Control and Prevention from March to July 2002. The serum samples were screened by ELISA method based on the XHFV nucleoprotein expressed in insect cells, and the positive and suspicious Positive results were confirmed by IFA test using HeLa cells expressing XHFV nucleoprotein. A total of 32 cases were confirmed after testing, all of whom had fever symptoms. The vast majority of patients have sudden onset and continuous fever (100%, up to 40.3°C). Fever is the earliest and inevitable symptom of the disease; limb weakness accounts for 100%, headache accounts for 84%, and chills and chills Accounted for 78%, epistaxis accounted for 75%, loss of appetite accounted for 69%,...

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Abstract

The invention relates to an application of compound e-jiao slurry in preparation of a medicine for preventing or treating Xingjiang haemorrhagic fever, and a pharmaceutical composition for preventing or treating Xingjiang haemorrhagic fever, wherein the pharmaceutical composition is composed of effective amount of compound e-jiao slurry in aspect of prevention or treatment and pharmaceutically acceptable carriers. The compound e-jiao slurry used for treating and preventing Xingjiang haemorrhagic fever diseases is disclosed for the first time in the invention; and the compound e-jiao slurry disclosed by the invention is beneficial to improving disease symptoms, recovering various indexes, shortening disease course, reducing complications and relieving pain of patients, and is capable of obviously increasing the contents of leukocyte and blood platelet of patients, shortening the blood coagulation time after bleeding, relieving symptoms, such as nausea, emesis and the like, increasing appetite and obviously improving gastroenteric functions.

Description

technical field [0001] The invention relates to a new application of compound donkey-hide gelatin, in particular to the application of the compound donkey-hide gelatin in the preparation of medicines for preventing or treating Xinjiang hemorrhagic fever, and belongs to the field of traditional Chinese medicines. Background technique [0002] Xinjiang hemorrhagic fever (XHF), also known as Crimean-Congo hemorrhagic fever (CCHF), its pathogen is Xinjiang hemorrhagic fever virus (XHFV), which was first discovered in southern Xinjiang in 1965 in my country The disease was prevalent, and antibodies to the virus were detected in people and animals in northern Xinjiang and areas outside Xinjiang, such as Qinghai, Yunnan, Sichuan, Inner Mongolia, Henan, and Anhui. [0003] After a person is infected with Xinjiang hemorrhagic fever virus, various clinical symptoms appear after an incubation period of 5-12 days, including fever, chills, headache, photophobia, general muscle pain, gastr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P31/14A61K35/36
Inventor 秦玉峰尤金花周祥山田守生张淹张路陈慧慧史兆松
Owner SHAN DONG DONG E E JIAO
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