Device used for replacing experimental tools and guaranteeing positioning accuracy for stereotaxic apparatus conveniently and rapidly and application method of device

A technology of positioning accuracy and locator, which is applied in the field of neurosurgery equipment, can solve the problems of reducing the stability of puncture or injection needles, affecting the reliability of experimental data, and taking a long time, so as to avoid the alignment adjustment process , good economic value and market prospects, and the effect of reducing labor

Active Publication Date: 2014-10-08
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In order to make the medical devices basically in the same stereotaxic position, the experimenters usually need to spend a long time to readjust the precise positions of different mechanical arms, which reduces the timeliness of brain tissue experiments, especially fresh brain tissue in vitro experiments, and affects the experimental results. credibility of the data
Generally, the needles of puncture needles and micro-injectors are elongated shafts with poor rigidity, which reduces the stability of the puncture or injection process
At present, there is almost no equipment to guide the puncture needle and microsyringe needle, and the needle will bend during the needle insertion process

Method used

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  • Device used for replacing experimental tools and guaranteeing positioning accuracy for stereotaxic apparatus conveniently and rapidly and application method of device
  • Device used for replacing experimental tools and guaranteeing positioning accuracy for stereotaxic apparatus conveniently and rapidly and application method of device
  • Device used for replacing experimental tools and guaranteeing positioning accuracy for stereotaxic apparatus conveniently and rapidly and application method of device

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0047] Utilize skull drill bit to carry out rabbit brain craniotomy experiment, the hollow rotating spindle used in this embodiment is the hollow rotating spindle (Direct Drive Spindles) designed and produced by U.S. Innova Design, Inc (U.S. innovation technology company), and its model is IDA60001; The experimental tool chuck (Three Jaw Gapless Micro Chuck) designed and produced by the American Innova Design, Inc (American innovative technology company) was selected, and the manual adjustment bracket was selected from the 60×60XY axis of the model LY60-LM produced by Shenzhen Huanlei Optoelectronics Technology Co., Ltd. The fine-tuning bracket, its assembly and use process is as follows:

[0048] A device for conveniently replacing experimental tools of a brain stereotaxic instrument and ensuring positioning accuracy, including a column 1, a first drive shaft 201, a first drive slider 202, a connecting plate 3, a spindle head, a microinjector drive device and a guide , wherei...

Embodiment 2

[0057] Needle insertion and injection and withdrawal procedures using a microsyringe:

[0058] A device for conveniently replacing experimental tools and ensuring positioning accuracy of a stereotaxic instrument, the structure is as described in Embodiment 1, the difference is that in the process of needle insertion, injection and extraction using a micro-injector 601, the guide The block 801 is fixedly arranged on the guide block fixing plate 802, and the guide hole 8011 matching the needle of the micro-injection used is selected at the same time.

[0059] Remove the skull drill 602 from the chuck 704 with adjustable clamping range, adjust the position of the platform base 804 on the Z-axis of the column, make it as close as possible to the position of the rabbit brain and lock it with screws. Take out the fixing ring 701 from the threaded connector 702, insert the microinjector 601 from the upper part of the spindle head, and the front end of the needle passes through the ap...

Embodiment 3

[0061] The experimental tool is replaced by a puncture needle, and the needle insertion and withdrawal process of the puncture needle:

[0062] A device for conveniently replacing experimental tools and ensuring positioning accuracy for a stereotaxic instrument. The structure is as described in Embodiment 2. The difference is that after the experimental tool is replaced with a puncture needle, a suitable guide hole 8011 and a puncture needle are selected. The needles match.

[0063] The first driving slider 202 is retreated, so that the needle of the microinjector 601 exits the guide hole 8011 of the guide block 801 . The fixing ring 701 is removed from the threaded connector 702, and the clip 704 with adjustable clamping range is adjusted to loosen the clamping of the needle of the micro-injection syringe 601. The microinjector push rod is taken out from the push rod connecting piece 5, and the microinjector 601 can be taken out from the spindle head. Then the puncture need...

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Abstract

The invention provides a device used for replacing experimental tools and guaranteeing the positioning accuracy for a stereotaxic apparatus conveniently and rapidly and an application method of the device. The device used for replacing the experimental tools and guaranteeing the positioning accuracy conveniently and rapidly comprises a stand column, a first driving shaft, a first driving sliding block, a connecting plate, a spindle head, a micro-syringe driving device and a guider, the first driving shaft and the guider are arranged at the two ends of the same side of the stand column respectively, the spindle head and the micro-syringe driving device are both fixedly arranged on the connecting plate, the connecting plate is fixedly connected with the first driving sliding block, and the first driving sliding block is arranged on the first driving shaft to slide. Through the spindle head adjustable in clamping range, clamping of the experimental tools of different types and different models is achieved. In addition, the guider, the spindle head and the micro-syringe driving device are used in a matched mode to guarantee the positioning accuracy of the experimental tools. The device solves the problem that in the traditional technology, a plurality of experimental clamping tools are needed, simplifies design of the clamping tools, and saves the troubles brought by the clamping tools, and meanwhile, the device is convenient to use, simple to operate and obvious in effect.

Description

technical field [0001] The invention relates to a device for conveniently replacing experimental tools and ensuring positioning accuracy, in particular to a device for conveniently replacing experimental tools and ensuring positioning accuracy during the use of a brain stereotaxic instrument, and belongs to the technical field of neurosurgery equipment. Background technique [0002] The animal brain stereotaxic instrument for scientific experiments is an important research equipment in the fields of neuroanatomy, neurophysiology, neuropharmacology and neurosurgery. In the establishment of animal models of Parkinson's disease, animal models of epilepsy, establishment of brain tumor models, learning and memory, neural stem cell transplantation in the brain, cerebral hypoxia, etc. [0003] Animal brain tissue experiments usually require precise completion of different experimental operations at the same site, such as directional puncture, injection, tissue extraction, etc. Dif...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61D7/00A61B19/00
Inventor 周军李岩邓建新岳鸿志李丽红
Owner SHANDONG UNIV
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