Lamellar corneal preserving solution

Abstract

The invention discloses a lamellar corneal preserving solution which is characterized by comprising components as follows: glycerol with the concentration of 200-500g / L, hyaluronic acid with the concentration of 5-50g / L, chondroitin sulfate with the concentration of 10-25 g / L, antioxidant with the concentration of 1-10g / L and buffer salt solution with the concentration of 10-40 mmol / L and PH of 6.0-8.0. The lamellar corneal preserving solution is suitable for storage of a lamellar corneal material, can maintain original collagenous fiber structure and transparency of the cornea, and prevents the collagenous fiber of the cornea from being damaged due to irradiation sterilization treatment.

Description

technical field [0001] The invention relates to the field of preservation of medical materials, in particular to a lamellar cornea preservation solution. Background technique [0002] Corneal blindness due to loss of corneal transparency is the second leading cause of vision loss after cataracts. Corneal transplantation can replace turbid or diseased corneal tissue, restore the original structure and transparency of the cornea, and achieve the purpose of protecting the eyeball structure and restoring the patient's vision. At present, corneal transplantation is divided into penetrating keratoplasty, lamellar keratoplasty and corneal endothelial transplantation according to the components of the graft and the operation method. The latter two component transplantations preserve part of the recipient corneal structure (endothelial layer or the previous structure of the endothelial layer), It has the advantages of less incidence of rejection and fewer long-term complications, an...

AI Technical Summary

Problems solved by technology

[0003] The corneal preservation solution materials reported in the past are only suitable for penetrating corneal transplantation or endothelial transplantation. The function of the preservation solution is to preserve the activity of endothelial cells, while lamellar corneal materials should pay more attention to the protection of corneal collagen fibers from the stroma layer. The research and development of transplantation preserves the cornea. The preservation solution of collagen fiber structure is particularly important

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