195results about How to "Protects against oxidative damage" patented technology

The present invention relates to isolated bioactive compositions containing bioactive fractions derived from Theacea plants. The present invention also relates to bioactive topical formulations containing the bioactive compositions. The present invention further relates to methods of using the bioactive compositions of the present invention, including, for example, methods for inhibiting inflammatory activity in skin tissue of a mammal, for protecting skin tissue of a mammal from ultraviolet light-induced damage, and for normalizing skin disorders in skin tissue of a mammal. The present invention also relates to methods for isolating bioactive fractions derived from cell juice or a cell walls component a Theacea plant.

A red blood cell storage composition includes a composition of red blood cells and biochemistry altering reagents, the biochemistry altering reagents being present at a concentration so as to reduce the percent hemolysis of the red blood cells during the freeze-thaw cycle below that of the percent hemolysis of the red blood cells in the absence the biochemistry altering reagents. The red blood cell storage composition preferably includes reagents selected from: modifiers of glycolytic / metabolic components, modifiers of antioxidant potential, effectors of intracellular ionic distribution, modifiers of membrane fluidity, modifiers of cytoskeletal structure, effectors of the cyclooxygenase second messenger pathway, effectors of the lipoxygenase second messenger pathway, effectors of the hexose monophosphate second messenger pathway, effectors of the phosphorylation second messenger pathway, modifiers of specific messenger molecules, and combinations thereof.

The invention is directed to therapeutic antioxidant compositions which are enhanced by the stabilized atomic hydrogen; one of the most potent antioxidants. Such products can be used for prophylactic and therapeutic purposes in treatment of cancer, diabetes, autoimmune diseases, neurodegenerative diseases, cardiovascular diseases, skin diseases etc. The products described can be used independently or in combination with other drugs and treatment modalities. The products can also be used as dietetic products to aid in desired weigh loss. The described products can also be used to prevent oxidative and free radical damage to food and oxidation-prone industrial products. The invention also describes the methods to produce and stabilize atomic hydrogen and prepare and use such stabilized / encaged atomic hydrogen enhanced antioxidant compositions.

The present invention relates to isolated bioactive compositions containing bioactive fractions derived from Theacea plants. The present invention also relates to bioactive topical formulations containing the bioactive compositions. The present invention further relates to methods of using the bioactive compositions of the present invention, including, for example, methods for inhibiting inflammatory activity in skin tissue of a mammal, for protecting skin tissue of a mammal from ultraviolet light-induced damage, and for normalizing skin disorders in skin tissue of a mammal. The present invention also relates to methods for isolating bioactive fractions derived from cell juice or a cell walls component a Theacea plant.

The invention relates to compositions and methods of treatment using an iron chelator, an antioxidant, estrogen, and / or combinations thereof, optionally, linked to a nanoparticle, to treat a subject in need thereof. The compositions and methods may be used to restore or protect the normal functions of osteoblast and osteoclast by depleting iron and inhibiting oxidative damage. The compositions and methods may also be used to increase the bone formation rate in a subject.

Disclosed are topical skin compositions and corresponding methods for their use that include plant extracts. One such composition can include a TNF-α inhibitor, wherein said inhibitor is an aqueous extract from the whole plant of Polygonum multiflorum, an antioxidant and a tyrosinase inhibitor, wherein said antioxidant and tyrosinase inhibitior is an aqueous extract from the whole plant of Lonicera japonica, and a dermatologically acceptable carrier, wherein the composition can include at least 50% by weight of water.

The present invention aims at providing one kind of natural plant-originated antisenility skin care factor for cosmetics preparation. Bamboo leaf general flavone has the beautifying effect of resisting free radical, resisting oxidation, resisting radiation, resisting bacteria, bacteriostasis, promoting proliferation of skin cells, preventing skin from oxidation damage, reducing melanin synthesis and delaying skin senility; and it has special scent,no irritation to skin and no allergic reaction. It may be applied in various cosmetics, such as nourishing agent, sun block skin care agent, anti-wrinkle whitening agent, face cleaning cream, shampoo, bathing cream, etc.

The invention discloses a lamellar corneal preserving solution which is characterized by comprising components as follows: glycerol with the concentration of 200-500g / L, hyaluronic acid with the concentration of 5-50g / L, chondroitin sulfate with the concentration of 10-25 g / L, antioxidant with the concentration of 1-10g / L and buffer salt solution with the concentration of 10-40 mmol / L and PH of 6.0-8.0. The lamellar corneal preserving solution is suitable for storage of a lamellar corneal material, can maintain original collagenous fiber structure and transparency of the cornea, and prevents the collagenous fiber of the cornea from being damaged due to irradiation sterilization treatment.

The invention discloses an anti-alcohol liver-protecting composition and anti-alcohol liver-protecting preparations comprising the composition, and relates to the technical field of food preparations.The anti-alcohol liver-protecting composition comprises 10-55 parts of corn oligopeptide, 2-20 parts of turmeric, 2-20 parts of kudzuvine root extract, 5-20 parts of raisin tree seed extract, and 0.5-23 parts of broccoli seed water extract. The invention also provides a preparation method of tablet-type, solid beverage-type and drink-type anti-alcohol liver-protecting preparations. The anti-alcohol liver-protecting preparations of the invention solve the problems that anti-alcohol liver-protecting products in the prior art have poor anti-alcohol effect, some traditional Chinese medicine ingredients have potential toxicity, and the product stability in actual production is difficult to ensure. The preparation method is simple and convenient.

The present invention relates to a combination of a hermetically sealed, substantially air-tight container, and a quinone-containing composition disposed therein. The container of the present invention is adapted for the convenient transport, and storage of an effective amount of an active ingredient, for example, ubiquinone, ubiquinol or a mixture thereof, and at least one pharmaceutically acceptable excipient. In another aspect the invention relates to a hermitically sealed container comprising an composition containing a single daily dose of ubiquinone, ubiquinol or both.

The invention relates to the field of medicaments, and provides a medicinal composition for improving reproductive capability and a preparation method and application thereof. The medicinal composition comprises vitamin E, coenzyme Q10 and / or selenium, and can be used for preparing a medicament and a health product for preventing and treating dysgenesis caused by oxidative stress, endocrine disorder or environmental factor induction when serving as a novel high-efficiency antioxidant. The medicinal composition has the advantages of improving the movement and vitality of sperms, increasing the secretion of sex hormones, protecting the functions of ovaries, improving immunity, improving conception rate, ensuring the nutrition of fetuses, and more effectively treating infertility by combining the conventional medicament vitamin E for treating the infertility and a novel therapeutic medicament coenzyme Q10 and / or selenium and applying different mechanisms for treating the infertility. Compared with any one component in the medicinal composition, the medicinal composition can not only effectively improve curative effect, but also overcome the defects when the components are singly used.

The present invention relates to a process for the production of glutathione, wherein said process comprises culturing a mutant yeast strain under conditions promoting glutathione production, and wherein said yeast strain has one or more genetic mutations that result in increased secretion of glutathione into the culture medium relative to a parental strain.

This invention relates to the use of a thylakoid extract that is preferably stabilized and activable for treating inflammation. Different types of cell or tissue targets and inflammatory stimuli have been used to evaluate the performance of the extract, which, in all cases successfully modulate inflammation through a balance of pro / anti-inflammatory cytokines. Compositions comprising the extract and other anti-inflammatory agents, namely glucocorticoids or NSAIDs are further disclosed and claimed.

The invention discloses sheep feed for promoting milk production. The sheep feed comprises, by weight, 15-25 parts of corn powder, 10-15 parts of barley, 10-20 parts of soybean meal, 8-10 parts of red biogas residues, 0.4-0.6 parts of sodium chloride, 12-16 parts of beer residues, 0.5-1 part of yeast, 0.3-0.5 parts of selenium methionine, 20-30 parts of clover silage, 15-20 parts of soya straws, 10-15 parts of cucurbit seedlings, 10-15 parts of peanut seedlings, 1.5-2.5 parts of a premix for sheep, 0.2-0.3 parts of sodium bicarbonate and 10-20 parts of an additive. The additive comprises beet pulp, fermented apple slag, sophora bud extract, soybean powder, tomato peel silage, seeds of cowherb, corn silks, radix astragali, ligusticum wallichii and licorice root. The sheep feed can promote lactation, improve inflammatory, virus and bacterium resistance and improve sheep immunity, has comprehensive nutrition and enough energy, has no toxic and side effects and does not produce drug resistance.

The invention discloses antioxidant composition. The antioxidant composition is prepared from the following raw materials: a polygonum cuspidatum extract, a turmeric extract, a green tea extract, alpha-lipoic acid and a coenzyme Q10. The invention further discloses a preparation method and application of the antioxidant composition. The antioxidant composition combines the polygonum cuspidatum extract, the turmeric extract, the green tea extract, the alpha-lipoic acid and the coenzyme Q10 for use, so that the antioxidant composition has a significant antioxidant effect, can effectively inhibit generation of oxygen free radicals, and can be used for treating and / or preventing ischemia-reperfusion injuries.

The present invention provides a new use for a thylakoid extract, that is for oral route of administration, and a composition comprising the thylakoid extract in adjunction with an acceptable carrier for oral administration. Besides the pharmaceutical use, the thylakoid extract enters the composition of food or food supplements, for its inocuity and its capacity to provide a diet enriched in anti-oxidants and anti-inflammatory compounds. Therefore, in accordance with the present invention is provided the use of a thylakoid extract in the making of an oral composition for treating or preventing a disease or disorder involving the formation of reactive oxygen species or inflammation. Also is provided a method for treating or preventing a disease or disorder involving the formal of reactive oxygen species or inflammation in an individual, which comprises the step of orally administering an effective dose of a thylakoid extract. Further is provided an oral composition comprising a thylakoid extract and a vehicle for oral ingestion or oral administration. An oral composition comprising purified thylakoids and a carrier for oral ingestion or oral administration, with the proviso that the carrier does not essentially consists of water, physiological saline or propylene glycol is also provided as food or a food supplement, or as a pellet, or encapsulated granules or powder. The carrier may be present in an amount of 0.01% to 95% (w / w) of the total composition. The purified thylakoids are present in an amount which achieves a dosage of 0.1 to 10 mg per Kg of a subject's body weight.

The invention is directed to therapeutic antioxidant compositions which are enhanced by the stabilized atomic hydrogen; one of the most potent antioxidants. Such products can be used for prophylactic and therapeutic purposes in treatment of cancer, diabetes, autoimmune diseases, neurodegenerative diseases, cardiovascular diseases, skin diseases etc. The products described can be used independently or in combination with other drugs and treatment modalities. The products can also be used as dietetic products to aid in desired weigh loss. The described products can also be used to prevent oxidative and free radical damage to food and oxidation-prone industrial products. The invention also describes the methods to produce and stabilize atomic hydrogen and prepare and use such stabilized / encaged atomic hydrogen enhanced antioxidant compositions.

A method for preventing metal-induced oxidative damage of hepatocytes, for inhibiting hepatocellular carcinogenesis, or for increasing carcinogen-metabolizing enzyme activity, which comprises administering to a subject an effective amount of an extract of a galenical composition comprising Panax pseudoginseng, Eucommiae ulmoides and Polygonati Rhizoma as essential components.

The invention discloses a microelement culture solution and a method for increasing microelements of pea sprouts with the same. The microelement culture solution is a solution containing one or more of 0.3-0.6 mg / L of zinc sulfate, 300-500 mg / L of organic selenium and 200-400 mg / L of germanium dioxide. The method for increasing the microelements of the pea sprouts comprises steps as follows: firstly, pea seeds are soaked in the microelement culture solution and then cultured, and the microelement culture solution is sprayed once every 12-24 h during culture. Compared with the prior art, the microelement culture solution and the method have the advantages as follows: the microelements of the cultured pea sprouts are high in enrichment degree, the microelement culture solution can also promote growth of the pea sprouts, production is not limited by seasons, the production cycle is short, the cost is low, the benefit is high, and the pea sprouts are natural and pollution-free.

The invention discloses an antioxidant skin-color-brightening composition and application thereof in cosmetics. The composition consists of the following components in percentage by mass: 0.5%-30% ofa moisture-preserving emollient, 0.05%-10% of an emulsifying stabilizer, 0.01%-20% of a synergetic antioxidant composition, 0.05%-20% of a synergetic skin-color-brightening composition, 0.01%-1% of aniron ion chelating agent composition, 0.003%-7% of an astaxanthin liposome compound, 0.01%-9% of a skin nutritional agent and 0.1%-3.0% of a preservative compound. Astaxanthin has a specific molecular structure and relatively strong activity, and the composition with stronger synergetically enhanced oxidation resistance and a synergetic skin-color-brightening effect is invented through last innovation based on the prior art; and natural astaxanthin is prepared into a liposome structure, and an iron ion chelating agent is added, so that the concentration of iron ions of a product system is controlled, the color-changing time of the appearance of the astaxanthin is prolonged, the structure of the product is preserved, and the storage time of the product system is prolonged.

The invention provides an antioxidant peptide in perilla seeds and an application thereof. The sequence of the antioxidant peptide is Tyr-Leu(YL). In vitro experiments show that the polypeptide can effectively remove ABTS, superoxide anions and various reactive oxide species (ORAC). Meanwhile, the peptide can effectively inhibit linoleic acid and rat liver lipid peroxidation. Cell experiments prove that the peptide is safe to cells and has obvious inhibiting effects on oxidative damages of the cell HepG-2. The antioxidant peptide has the characteristics of simple structure, safety, strong antioxidation activity, and the like, can serve as an excellent substitute for existing synthetic antioxidants and has important value for development and application of novel antioxidant health care products and food additives.

A method for isolating a mixture of anthocyanins, bioflavonoids and phenolics from an edible berry using adsorbent resins which are regenerable for reuse is described. The mixture with a consumable carrier is particularly useful in foods and as a dietary supplement or nutraceutical product.

The invention discloses an elsholtzia ciliata hyland extract, a preparation and an application thereof. The elsholtzia ciliata hyland extract is prepared by virtue of water extraction, has the effects of remarkably resisting free radicals, oxidation and radiation, resisting and inhibiting bacteria, promoting skin cell proliferation, protecting skin from ultraviolet injury and preventing skin from oxidation injury. By virtue of the characteristics, the elsholtzia ciliata hyland extract has the functions of preventing oxidation injury of skin, reducing melanin synthesis and delaying skin senescence, and has remarkable effects of allergy and senescence resistance when being applied to cosmetics.

A process for the synthesis of an Exochelin comprising the steps of generating L-N-[(2-benzyloxy-(benzoyl)] serine or L-N-[2-benzyloxy (benzoyl)] threonine, creating L-N-t-Boc- epsilon -hydroxynorleucine and reacting same to produce L-N-Boc- epsilon -bromonorleucine trimethylsilylethyl ester, providing a dicarboxylic acid and forming an O-benzyl methyl hydroxamate from the dicarboxylic acid, coupling the O-benzyl methyl hydroxamate with the L-N-Boc- epsilon -bromonorleucine trimethylsilylethyl ester to give an L-N2-Boc-N6-methyl,N6-(benzyloxy) lysine 2-trimethylsilylethyl ester which incorporates the dicarboxylic acid as modified above, removing the N-tert-butoxycarbonyl protecting group from the L-N2-Boc-N6-methyl, N6-(benzyloxy) lysine 2-trimethylsilylethyl ester to yield a substituted lysine, and coupling the same with the L-N-[2-benzyloxy (benzoyl) serine or -threonine to yield a 2-trimethyl silylethyl ester of dibenzyl Exochelic acid, transforming the 2-trimethyl silylethyl ester of dibenzyl Exochelic acid to dibenzyl Exochelic acid, preparing benzyl epi-cobactin, forming an ester bond between the dibenzyl Exochelic acid and benzyl epi-cobactin to form an intermediate, and, hydrogenolytically removing three benzyl groups from said intermediate, resulting in the synthesized Exochelin. More particularly, a synthesis for Exochelin 786SM (R) is disclosed wherein the dicarboxylic acid is suberic acid and the serine form is utilized.

The invention discloses a method for improving winter resistance of turf by adopting household garbage compost offscourings. The ryegrass seedlings cultivated by compost and cold-hardened in cold environment with gradually decreased temperature have no obvious difference from the seedlings in the control group in indexes such as protective enzyme, proline and conductivity, but are slightly shorter. The aboveground biomass of the cold-hardened ryegrass seedlings cultivated by compost offscourings is reduced by 26.74% compared with that of the seedlings in the control group and is reduced by 23.21% compared with that of the seedlings with relatively poorer matix nutrition in the filter paper group. The final technical effect shows that the cold-hardened turf can fully resist winter in the winter environment of not less than 10 DEG C below zero in the outdoor balcony without being provided with a heating facility, and the aim of storing the turf in winter and producing all year around is achieved.

A method for providing thermotolerance of a plant and the genetic engineering applications thereof are disclosed. DNA fragment containing a gene encoded EXPORTIN1A is transferred into a plant cell to provide or enhance thermotolerance of the plant. The method can be applied in genetic engineering to select transgenic plant.

The invention discloses blue-ray-resisting cream and a preparation method thereof. The blue-ray-resisting cream is prepared from the following components: EDTA-2Na (Ethylenediaminetetraacetic Acid Disodium Salt), butylene glycol, glycerol, betaine, sodium hyaluronate, niacinamide, allantoin, maltooligosyl glucoside, hydrogenated starch hydrolysate, a thickening agent, an emulsifier, polydimethyl siloxane, mineral jelly, a surfactant, glyceryl stearate / PEG (Polyethylene Glycol)-100 stearate, cetearyl alcohol, glyceryl stearate, polyglycerol-3 methyl glucose distearate, cyclomethicone, triethanolamine, phenoxyethanol, ethylhexylglycerin, caprylic / capric triglyceride, mung bean extract, oatmeal extract, polydimethyl siloxane, lecithin, flos buddlejae extract, hedychium coronarium root extract, coffea arabica seed extract and pure water. The blue-ray-resisting cream provided by the invention can be used for reducing active oxygen and free radicals generated by blue-ray radiation and enhancing the protection on skin, so that damage caused by blue ray to the skin can be reduced.

The invention relates to the technical field of agricultural environment conservation and restoration, in particular to a repairing agent for treating alkaline cadmium-contaminated soil and a preparation method thereof. The preparation method comprises the following steps: weighing blast furnace slag, sepiolite, bentonite and flue gas desulfurization gypsum in proportion, uniformly mixing, addingfulvic acid, and mixing to obtain the repairing agent. The preparation method of the invention has the following advantages: the raw materials are easily available; the operation is simple; the preparation cost of the repairing agent can be controlled within 800 yuan / ton, the dosage per acre is 100-300 kg, the cost of the repairing agent per acre is only 80-240 yuan, and the repairing agent can bewidely promoted and used at large scale. By the principle of multi-dimensional repairing, the activity of cadmium in soil can be reduced through sedimentation, adsorption and complexation, and the upward transfer of cadmium in crops can be inhibited through deposition on the endodermis and formation of -SH (sulfhydryl). The two-pronged approach makes it possible to effectively reduce the contentof cadmium in agricultural products.

The invention relates to a retina pigment epithelial cell culture medium and an application thereof. The retina pigment epithelial cell culture medium comprises a first RPE (Retinal Pigment Epithelium) cell culture medium and a second RPE cell culture medium, wherein the first RPE cell culture medium and the second RPE cell culture medium are respectively used in 1.5 weeks, a RPE monolayer cell needed for cell replacement therapy can be quickly cultured; and the cultured RPE is polygonal, embedded and polarly-arranged monolayer cell and has the normal biological functions. Compared with the prior art, the RPE monolayer cell needed for cell replacement therapy can be quickly cultured in 1.5 weeks under the precondition that the conventional laboratory consumables are used; and the retina pigment epithelial cell culture medium is relatively low in cost and high in proliferation speed.