Pharmaceutical composition for treating impaired glucose regulation and preparation method thereof

A composition and drug technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve problems such as hypoglycemia and patient difficulty, and achieve the reduction of fasting blood sugar and postprandial blood sugar, definite curative effect, and combination square unique effect

Active Publication Date: 2014-12-03
BEIJING UNIV OF CHINESE MEDICINE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the existing chemical drugs for the treatment of diabetes, such as sulfonylureas, insulin sensitizers, metformin, and α-glucosidase inhibitors, can be used to treat IGR, they can easily lead to hypoglycemia and induce myocardial infarction, which is unbearable for ordinary patients.

Method used

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  • Pharmaceutical composition for treating impaired glucose regulation and preparation method thereof
  • Pharmaceutical composition for treating impaired glucose regulation and preparation method thereof
  • Pharmaceutical composition for treating impaired glucose regulation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0146] The raw materials were weighed according to the following proportions: 170 parts of balsam pear extract, 180 parts of Polygonatum odoratum extract, 170 parts of mulberry leaf extract, 30 parts of Panax notoginseng extract, 20 parts of cinnamon extract, and 0.5 part of chromium picolinate.

[0147] Preparation:

[0148] (1) Weighing: Weigh bitter gourd extract, Polygonatum odoratum extract, mulberry leaf extract, Panax notoginseng extract, cinnamon extract, chromium picolinate according to the formula, pass through a 60-mesh sieve respectively, and set aside;

[0149] (2) Mixing: take the whole amount of chromium picolinate, and another equivalent amount of cinnamon extract, after the two are mixed evenly, then take the same amount of cinnamon extract as the above-mentioned mixed powder and mix evenly, repeat the above operation until Mix all the cinnamon extract with chromium picolinate evenly to obtain mixed powder I; mix mixed powder I with Panax notoginseng extract f...

Embodiment 2

[0157] The raw materials were weighed according to the following proportions: 60 parts of balsam pear extract, 60 parts of Polygonatum odoratum extract, 60 parts of mulberry leaf extract, 20 parts of Panax notoginseng extract, 20 parts of cinnamon extract, and 0.05 part of chromium picolinate.

[0158] Preparation:

[0159] (1) Weighing: Weigh bitter gourd extract, Polygonatum odoratum extract, mulberry leaf extract, Panax notoginseng extract, cinnamon extract, chromium picolinate according to the formula, pass through a 60-mesh sieve respectively, and set aside;

[0160] (2) Mixing: take the whole amount of chromium picolinate, and another equivalent amount of cinnamon extract, after the two are mixed evenly, then take the same amount of cinnamon extract as the above-mentioned mixed powder and mix evenly, repeat the above operation until Mix all the cinnamon extract with chromium picolinate evenly to obtain mixed powder I; mix mixed powder I with Panax notoginseng extract for...

Embodiment 3

[0168] The raw materials were weighed according to the following proportions: 125 parts of bitter gourd extract, 166.67 parts of Polygonatum odoratum extract, 133.33 parts of mulberry leaf extract, 33.33 parts of Panax notoginseng extract, 8.33 parts of cinnamon extract, and 0.13 parts of chromium picolinate.

[0169] Preparation:

[0170] (1) Weighing: Weigh bitter gourd extract, Polygonatum odoratum extract, mulberry leaf extract, Panax notoginseng extract, cinnamon extract, chromium picolinate according to the formula, pass through a 60-mesh sieve respectively, and set aside;

[0171] (2) Mixing: take the whole amount of chromium picolinate, and another equivalent amount of cinnamon extract, after the two are mixed evenly, then take the same amount of cinnamon extract as the above-mentioned mixed powder and mix evenly, repeat the above operation until Mix all the cinnamon extract with chromium picolinate evenly to obtain mixed powder I; mix mixed powder I with Panax notogin...

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Abstract

The invention relates to a pharmaceutical composition for treating impaired glucose regulation and a preparation method thereof. The pharmaceutical composition is mainly composed of a bitter gourd extract, a polygonatum odoratum extract, a mulberry leaf extract, a pseudo-ginseng extract, a cinnamomum cassia presl extract and chromium picolinate, and is a medicament prepared by adopting a pharmaceutically acceptable carrier or excipient, wherein the medicament includes capsules, granules, tablets, pills and the like. The pharmaceutical composition has the efficacies of supplementing qi, nourishing yin, clearing heat and activating blood, and is suitable for patients with impaired glucose regulation and early-stage and mild diabetes to take. Clinical studies show that the pharmaceutical composition can reduce fasting blood-glucose and postprandial blood glucose and has no toxic or side effect.

Description

1. Technical field [0001] The invention relates to a pharmaceutical composition for treating impaired sugar regulation and a preparation method thereof. 2. Background technology [0002] Impaired glucose regulation (IGR) refers to blood glucose that is higher than normal but has not yet reached the diagnostic criteria for diabetes, including impaired fasting glucose (IFG) and impaired glucose tolerance (IGT). IGR is pre-diabetes, a dangerous stage of developing diabetes. In 2010, the "New England Journal of Medicine" published the results of the survey on the prevalence of diabetes in my country by the "Chinese Diabetes and Metabolic Syndrome Research Group" of the Diabetes Branch of the Chinese Medical Association. The survey shows that the prevalence of diabetes in men and women over the age of 20 in my country is 10.6% and 8.8%, respectively, and the overall prevalence has reached 9.7%. The prevalence of prediabetes during the same period was as high as 15.5%. The calc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P3/10A61K31/555
Inventor 刘铜华
Owner BEIJING UNIV OF CHINESE MEDICINE
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