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Tea tree essential oil antimicrobial gel for treating vaginal disease in gynecology

A technology for tea tree essential oil and vaginal diseases, which is applied in the directions of sexual diseases, topical antibacterial agents, and resistance to vector-borne diseases, etc., can solve the problems of wound repair, cumbersome preparation process, poor efficacy, etc. Inhibitory effect, good effect

Inactive Publication Date: 2014-12-24
HAINAN HOTMED TIANYA PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The above situation shows that the existing drugs for the treatment of gynecological vaginal diseases have large side effects and poor curative effect, resulting in strong dependence of patients, which is not conducive to the physical and psychological trauma repair of the majority of gynecological disease patients.
Although the latest research results on the treatment of vaginal diseases have appeared, for example, the invention patent with the publication number CN103385926A discloses an "antibacterial gel for the treatment of gynecological cervical and vaginal diseases", but its preparation process is cumbersome, and the prescription components contain Partial ethanol, the irritation will increase significantly, and components such as borneol are easy to separate out, and tea tree oil will also separate

Method used

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  • Tea tree essential oil antimicrobial gel for treating vaginal disease in gynecology
  • Tea tree essential oil antimicrobial gel for treating vaginal disease in gynecology
  • Tea tree essential oil antimicrobial gel for treating vaginal disease in gynecology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] Utilize the component of above-mentioned weight to prepare the method for the tea tree essential oil antibacterial gel for the treatment of gynecological vaginal diseases, comprising the following steps:

[0042] (a) Add 80% purified water to the emulsification tank, then add polyoxyethylene 60 hydrogenated castor oil, and fully dissolve after stirring at a slow speed with an emulsifier;

[0043] (b) Add the mixture of sodium methylparaben, sodium propylparaben, glycerin and citral to the gained in step (a), fully dissolve after stirring at a slow speed with an emulsifier;

[0044] (c) adding tea tree essential oil to the obtained step (b), using an emulsifier to stir and emulsify for 30 minutes under the condition that the rotating speed gradually increases, to obtain a milky white solution;

[0045] (d) Divide polycarbophil and carbomer 934 into three equal parts after mixing, slowly and evenly add the first equal part to the obtained step (c), and use an emulsifier t...

Embodiment 2

[0053] The tea tree essential oil antibacterial gel for treating gynecological vaginal diseases was prepared by using the above-mentioned components, and the polyoxyethylene 60 hydrogenated castor oil in Example 1 was replaced with polyoxyethylene 40 hydrogenated castor oil, and the preparation process was the same as in Example 1.

[0054] Example 3

Embodiment 3

[0056] Utilize the above-mentioned components to prepare the tea tree essential oil antibacterial gel for the treatment of gynecological vaginal diseases, the mixed components of polycarbophil and carbomer 934 in embodiment 1 are replaced by only retaining carbomer 934 components, preparation process With embodiment 1.

[0057] Example 4

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Abstract

The invention discloses a tea tree essential oil antimicrobial gel for treating a vaginal disease in gynecology. Every 1000 parts by weight of gel contains the following raw material components: 1 to 100 parts of tea tree essential oil, 0.5 to 20 parts of emulsifier, 1 to 50 parts of biological adhesive material and the balance of modified components and purified water. The tea tree essential oil is added into the high-molecular biological adhesive material to carry out solubilizer screening, so that the obtained tea tree essential oil gel has good biocompatibility, and is small in irritation and has no delayed type hypersensitivity in an actual application process. The clinical test proves that after the prepared tea tree essential oil gel is squeezed into the vagina of a female by virtue of a gel applicator, the tea tree essential oil contained in the prepared tea tree essential oil gel can be used for effectively inhibiting staphylococcus aureus, escherichia coli and candida albicans in the vagina and the cervix uteri, and rapidly relieving itching, removing peculiar smells and performing restoration and regeneration; and by virtue of a buffering ability of the tea tree essential oil gel, the weak acidity of normal physiology of the vagina can be maintained, and the moisture content of the vagina is supplemented at the same time so as to exert a lubricating function.

Description

technical field [0001] The invention belongs to the field of drug synthesis, in particular to a tea tree essential oil antibacterial gel for treating gynecological vaginal diseases. Background technique [0002] With the development of society and the constant changes in people's lifestyles and behaviors, the prevalence of various gynecological diseases, such as reproductive tract infections, menstrual disorders and breast diseases, is gradually increasing. Gynecological infectious diseases are a common and frequently-occurring disease, especially mycotic vaginitis, cervical erosion and senile vaginitis, which have a high incidence rate, and various chronic cervical diseases have plagued the majority of female friends all year round. [0003] For example, simple vulvovaginal candidiasis (SVVC) is a gynecological reproductive tract infection caused by the excessive reproduction of Candida in the vagina. The most common infection is Candida albicans, with a prevalence of about...

Claims

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Application Information

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IPC IPC(8): A61K36/61A61K47/32A61K9/06A61P15/02A61P31/02
CPCY02A50/30
Inventor 方通覃俊杰曾佳烽潘俊芳
Owner HAINAN HOTMED TIANYA PHARMA
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