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Degradable polymer support as well as forming method and application thereof

A biological and font-shaped technology, applied in stents, medical science, surgery, etc., can solve the problems of cumbersome and complicated preparation processes, achieve the effects of simple operation, good radial force and flexibility, and reduce production costs

Active Publication Date: 2015-01-14
BEIJING ADVANCED MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

But described method is divided into many steps equally, and preparation process is loaded down with trivial details and complicated

Method used

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  • Degradable polymer support as well as forming method and application thereof
  • Degradable polymer support as well as forming method and application thereof
  • Degradable polymer support as well as forming method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 11

[0076] A degradable polymer stent, using PLLA as a raw material, the molecular weight of PLLA is 800,000, adopting the same zigzag processing route, the specific processing steps are as follows:

[0077] 1) The structure of the vascular stent is designed to be cylindrical by computer program;

[0078] 2) Automatically or manually generate a vascular stent processing program according to the designed vascular stent structure;

[0079] 3) Set the operating parameters of the extruder and wait for the equipment to reach the set parameter value;

[0080] 4) adding PLLA pellets into the silo of the equipment, and the extruder extrudes fibers sequentially according to the routing path set in the control system to prepare the degradable vascular stent;

[0081] 5) The extruded vascular stent is used in the subsequent crimping process.

[0082]The prepared PLLA stent is a cylindrical stent with a size of 6×40 mm. The prepared PLLA stent is used as a peripheral vascular stent. The ste...

Embodiment 12

[0083] Example 1.2, a degradable polymer stent, is the same as Example 1.1, except that the size of the vascular stent is 6×60 mm.

Embodiment 13

[0084] Example 1.3, a degradable polymer stent, is the same as Example 1.1, except that the size of the vascular stent is 6×80 mm.

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Abstract

The invention discloses an in vivo degradable support as well as a forming method and an application thereof. The in vivo degradable support is made from a biodegradable material, and an internal structure of the in vivo degradable support is Z-shaped and / or woven structure, a circular structure, a circular double chamfer structure and a woven parallel bridge structure. The forming method needs to utilize a rapid moulding system, wherein the rapid forming system comprises extrusion moulding equipment, a four-axis positioning system and an operating system for controlling production conditions. After a program is edited by utilizing a control system, fiber filaments extruded by extrusion equipment can be wound according to a structure set in the edited program; and the program can be easily changed, an ideal vascular scaffold can be prepared more easily, and better radial support force can be realized.

Description

technical field [0001] The invention relates to a stent and its forming processing and application, in particular to an in vivo degradable polymer stent and its forming processing method and application. Background technique [0002] When blood vessels are narrowed or occluded due to lesions in the human body, it is usually necessary to adopt a vascular stent implanted in the blood vessels of the diseased segment by means of interventional therapy. Used to support blood vessels and restore blood flow. Some vascular stents also have the effect of preventing restenosis. Vascular stents are usually made of metal or polymer materials. First, the vascular stent is pressed on the balloon catheter, and the vascular stent is delivered to the lesion by interventional methods. After the stent is stretched, it is placed on the vascular lesion site. Vascular stents can be left in human blood vessels for a long time or temporarily. Vascular stents can be used in cardiovascular and ce...

Claims

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Application Information

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IPC IPC(8): A61L31/14A61L31/16A61L31/06A61L31/04A61F2/90B29C47/00
Inventor 赵庆洪贾钰婕刘青赵清华
Owner BEIJING ADVANCED MEDICAL TECH
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