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A traditional Chinese medicine composition for treating post-immunosuppressive fungal keratitis and its preparation method

A technique for fungal keratitis and immunosuppression, applied in the field of traditional Chinese medicine, can solve problems such as no fungal keratitis found

Inactive Publication Date: 2017-07-21
河南省立眼科医院 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no literatures, reports or published patents on traditional Chinese medicine compound prescriptions for fungal keratitis caused by immunosuppression.

Method used

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  • A traditional Chinese medicine composition for treating post-immunosuppressive fungal keratitis and its preparation method
  • A traditional Chinese medicine composition for treating post-immunosuppressive fungal keratitis and its preparation method
  • A traditional Chinese medicine composition for treating post-immunosuppressive fungal keratitis and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0048] The traditional Chinese medicine composition used for the treatment of post-immunosuppressive fungal keratitis in this example consists of the following raw materials in parts by weight: 30 parts of Sunburned Astragalus, 30 parts of Codonopsis pilosula, 12 parts of fried Atractylodes macrocephala, 9 parts of fried Atractylodes rhizome, and 15 parts of rehmannia glutinosa. 30 parts of yam, 12 parts of medlar, 12 parts of Ligustrum lucidum, 9 parts of bitter almond, 6 parts of white coix seed, 30 parts of coix seed, 12 parts of light bamboo leaf, 9 parts of Magnolia officinalis, 12 parts of honeysuckle, 15 parts of wild chrysanthemum, Dandelion 15 parts, white peony root 15 parts, angelica 12 parts, chuanxiong 9 parts, safflower 9 parts, windproof 9 parts, Bupleurum 9 parts, licorice 9 parts.

[0049] The preparation method of the traditional Chinese medicine composition for the treatment of fungal keratitis after immunosuppression in the present embodiment comprises the f...

Embodiment 2

[0054] The traditional Chinese medicine composition used for treating post-immunosuppressive fungal keratitis in this example is composed of the following raw materials in parts by weight: 20 parts of Radix Astragali Radix, 20 parts of Codonopsis Radix, 10 parts of Fried Atractylodes Rhizoma Atractylodes Rhizome, 6 parts of Fried Rhizoma Atractylodes Rhizome, 12 parts of Rehmannia glutinosa 20 parts of yam, 10 parts of medlar, 10 parts of Ligustrum lucidum, 6 parts of bitter almond, 6 parts of white coix seed, 20 parts of coix seed, 10 parts of light bamboo leaf, 6 parts of Magnolia officinalis, 10 parts of honeysuckle, 10 parts of wild chrysanthemum, 10 parts of dandelion, 12 parts of white peony, 10 parts of angelica, 6 parts of Chuanxiong, 6 parts of safflower, 6 parts of Fangfeng, 6 parts of Bupleurum, and 6 parts of licorice.

[0055] In this example, the preparation method of the traditional Chinese medicine composition for treating post-immunosuppressive fungal keratitis...

Embodiment 3

[0057] The traditional Chinese medicine composition used for the treatment of post-immunosuppressive fungal keratitis in this example consists of the following raw materials in parts by weight: 9 parts of Radix Astragali Radix, 9 parts of Codonopsis Radix, 6 parts of Fried Atractylodes Rhizoma Atractylodes Rhizome, 3 parts of Fried Rhizoma Atractylodes Rhizome, 9 parts of Rehmannia glutinosa 15 parts of Chinese yam, 6 parts of medlar, 6 parts of Ligustrum lucidum, 6 parts of bitter almond, 3 parts of white coix seed, 9 parts of coix seed, 6 parts of light bamboo leaf, 3 parts of Magnolia officinalis, 6 parts of honeysuckle, 9 parts of wild chrysanthemum, 9 parts of dandelion, 6 parts of white peony, 6 parts of angelica, 3 parts of Chuanxiong, 3 parts of safflower, 6 parts of Fangfeng, 3 parts of Bupleurum, and 3 parts of licorice.

[0058] In this example, the preparation method of the traditional Chinese medicine composition for treating post-immunosuppressive fungal keratitis...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating mycotic keratitis after immune suppression and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises 23 Chinese herbal medicine compatibility components comprising radix astragali preparata, codonopsis pilosula, roasted rhizoma atractylodis macrocephalae, rehmannia glutinosa and the like. As for symptoms of spleen and kidney deficiency, deficiency of both qi and yin and wet and hot blood stasis after an immune suppressor is applied, the traditional Chinese medicine composition has the beneficial effects of tonifying kidney and spleen, tonifying qi and yin, clearing heat and promoting dieresis, activating blood and removing stasis; and as for root causes of fungus toxin infecting, the medicines for killing fungi are mainly used for clearing away heat and toxic materials. According to the overall policy, both symptoms and root causes of complex pathogenesis can be treated. Use of the traditional Chinese medicine composition has the advantages that body resistance strengthening and evil eliminating are carried out at the same time to prevent the body from being injured by the evil; the kidney and the spleen are tonifyed at the same time so that the bermorgen is tonifyed and congenital factors are benefited; warm and cold are used at the same time so that the overall formula is warm without drying and clear without cold; blood enriching is carried out while blood circulation invigorating is carried out, and stasis removing is carried out while the blood is not injured; and the use of the medicine composition meets the requirement of traditional Chinese medicine theories, is supported by modern pharmacology studying, and finally the traditional Chinese medicine composition is efficient and gentle.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating post-immunosuppressive fungal keratitis and a preparation method of the traditional Chinese medicine composition, belonging to the technical field of traditional Chinese medicine. Background technique [0002] Corneal fungal infection is a common blinding and infectious eye disease in clinical practice. It is caused by pathogenic fungus infection of the cornea. It is the main cause of suppurative keratitis and corneal transplantation in my country, and the first cause of corneal blindness. This disease is often faced by ophthalmology clinicians. It is a dangerous disease, but it is very difficult to treat. The main reason is that the treatment of fungi is inherently difficult, and the special structure of the cornea and the ocular surface barrier make it difficult for antifungal drugs to penetrate into the cornea. Therefore, fungal keratitis is a kind of keratitis that is ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9064A61P27/02A61P31/10
CPCA61K9/0053A61K9/08A61K36/232A61K36/233A61K36/236A61K36/238A61K36/284A61K36/286A61K36/287A61K36/288A61K36/344A61K36/355A61K36/481A61K36/484A61K36/575A61K36/638A61K36/65A61K36/71A61K36/736A61K36/804A61K36/815A61K36/8945A61K36/899A61K36/8994A61K36/9064A61K2236/331A61K2236/39A61K2236/53A61K2300/00
Inventor 张红敏陈世伟郑攀贺司宇刘素素郑宏郑启仲王丽英安利娜黄霄
Owner 河南省立眼科医院
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