Chewing medicine composition for preventing and treating mouth, nose and throat upper respiratory infecting and application thereof

A technology of upper respiratory tract and composition, applied in the field of chewing gum-type pharmaceutical preparations, can solve the problems of increased pain, bad taste, high irritation and the like

Inactive Publication Date: 2015-02-11
陆媛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, a variety of Western medicines and some traditional Chinese medicine ingredients commonly used to treat oral, nose, throat, and upper respiratory tract infections have good effects or bad taste. They are usually bitter, have a strange or heavy taste, and are not easily accepted by users. It can be swallowed, but it is difficult for people to accept chewing, or it is highly irritating, and it is easy to

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0084]Each tablet (or each grain) of the main component of the representative compound preparation of the present invention contains: diclofenac sodium (diclofenac) 15mg, artificial bezoar 15mg, chlorpheniramine maleate (chlorpheniramine) 2.5mg; auxiliary materials add chewing colloid, Food coloring, food flavoring, etc. The amount of excipients is used to reduce the relative "concentration" of the drug that is not suitable for direct chewing, slow down the drug release, improve the taste of chewing and be easily accepted by patients, and protect the mucous membrane from being damaged.

[0085] Product design requirements: chewing does not hurt the mucous membrane, the taste is easy to accept, and the symptoms are relieved after chewing. Early oral, nose, throat and upper respiratory tract infection can be cured by chewing one tablet or one tablet. If the disease is slightly severe, the dosage and frequency of chewing can be increased. 1-2 tablets or capsules at a time, 1-4 ta...

Embodiment 2

[0098] In the past two months, the applicant has mass-produced chewing gum drugs of three formulations in the laboratory (these three drugs are all based on conventional chewing gum raw materials, respectively loaded with traditional sulfonamides, cephalosporins, For macrolide medicines, after the raw materials are evenly mixed, the traditional chewing gum process is used to prepare pharmaceutical chewing gum with a chewing time of about 15 minutes per piece, and the concentration of active ingredients in the chewing gum is reduced to 1 / 30 of the original medicine concentration Left and right) for the treatment of oral, nose, throat and upper respiratory tract infections, 62 cases of about 300 times of chewing administration tests have been carried out, all reflecting that the therapeutic effect of chewing administration is significantly better than that of traditional swallowing administration. Most of the chewing gum drug testers are patients with early upper respiratory trac...

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Abstract

The invention provides a chewing medicine composition for preventing and treating mouth, nose and throat upper respiratory infecting and application thereof. The medicine composition comprises effective constituents used for preventing and/or treating mouth, nose and throat upper respiratory infecting symptoms or early-stage mouth, nose and throat upper respiratory infecting complication signs, and acceptable accessories of medicines; the medicine composition further comprises auxiliary constituents; the effective constituents used for preventing and/or treating the mouth, nose and throat upper respiratory infecting symptoms or the early-stage mouth, nose and throat upper respiratory infecting complication signs comprise medicine constituents which are not suitable for direct containing and direct chewing; and the proportion of the acceptable accessories of the medicines to the chewing medicine composition is larger than the proportion of accessories to traditional swallowing medicines used for preventing and/or treating mouth, nose and throat upper respiratory infecting. By means of the technology of the chewing medicine composition, the medicines which are unacceptable, not suitable for direct chewing or forbidden in chewing are prepared into a safely-contained efficient medicine preparation welcomed by patients; and the chewing medicine composition has the obvious effect on preventing and treating the mouth, nose and throat upper respiratory infecting.

Description

technical field [0001] The present invention relates to a pharmaceutical composition for preventing and treating oral, nose, and throat upper respiratory tract infections and its application, in particular to a pharmaceutical composition for preventing and treating oral, nose, and throat upper respiratory tract infections that are traditionally considered to be unsuitable for oral administration and chewing. Technology for forming highly efficient chewing pharmaceutical composition and chewing gum (chewing gum) oral preparation, the prepared chewing gum oral pharmaceutical preparation and related applications. Background technique [0002] Upper respiratory tract infection (the most common is early cold, upper respiratory tract infection of mouth, nose, throat and upper respiratory tract infection) has a fast onset, and if the medicine can be taken in time and early, the effect will be quick. [0003] At present, the drugs for the prevention and treatment of upper respirator...

Claims

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Application Information

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IPC IPC(8): A61K45/00A61K45/06A61P11/00A61P11/02A61P11/04
Inventor 陆媛
Owner 陆媛
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