Chewing medicine composition for preventing and treating mouth, nose and throat upper respiratory infecting and application thereof
A technology of upper respiratory tract and composition, applied in the field of chewing gum-type pharmaceutical preparations, can solve the problems of increased pain, bad taste, high irritation and the like
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Embodiment 1
[0084]Each tablet (or each grain) of the main component of the representative compound preparation of the present invention contains: diclofenac sodium (diclofenac) 15mg, artificial bezoar 15mg, chlorpheniramine maleate (chlorpheniramine) 2.5mg; auxiliary materials add chewing colloid, Food coloring, food flavoring, etc. The amount of excipients is used to reduce the relative "concentration" of the drug that is not suitable for direct chewing, slow down the drug release, improve the taste of chewing and be easily accepted by patients, and protect the mucous membrane from being damaged.
[0085] Product design requirements: chewing does not hurt the mucous membrane, the taste is easy to accept, and the symptoms are relieved after chewing. Early oral, nose, throat and upper respiratory tract infection can be cured by chewing one tablet or one tablet. If the disease is slightly severe, the dosage and frequency of chewing can be increased. 1-2 tablets or capsules at a time, 1-4 ta...
Embodiment 2
[0098] In the past two months, the applicant has mass-produced chewing gum drugs of three formulations in the laboratory (these three drugs are all based on conventional chewing gum raw materials, respectively loaded with traditional sulfonamides, cephalosporins, For macrolide medicines, after the raw materials are evenly mixed, the traditional chewing gum process is used to prepare pharmaceutical chewing gum with a chewing time of about 15 minutes per piece, and the concentration of active ingredients in the chewing gum is reduced to 1 / 30 of the original medicine concentration Left and right) for the treatment of oral, nose, throat and upper respiratory tract infections, 62 cases of about 300 times of chewing administration tests have been carried out, all reflecting that the therapeutic effect of chewing administration is significantly better than that of traditional swallowing administration. Most of the chewing gum drug testers are patients with early upper respiratory trac...
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