Preparation method and application of quick absorption saturation gelation seaweed hemostatic dressing

A technology of hemostatic dressing and liquid gel, which is applied in the field of rapid liquid-absorbing and gelling seaweed hemostatic dressing, can solve the problems of limited moisture absorption and gelation speed, restrictions on the application of seaweed dressings, and slow moisture absorption speed of the product, achieving The effects of promoting wound healing, green production environment, and isolating bacterial infection

Inactive Publication Date: 2015-02-11
许春晖 +1
View PDF9 Cites 19 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, it takes at least 30 minutes for the dressing made of ordinary calcium alginate fiber to absorb the exudate or pus and convert it into a gel, which is still difficult to meet for the wound cleaning and nursing of acute massive bleeding or exudate. requirements, restricting the clinical application of seaweed dressings
[0004] For this problem, the current technical solution is generally to modify the fiber by reducing the level of fiber calcification during spinning or blending into other absorbable materials, but the reduction of the degree of calcification or the introduction of blended substances often As a result, the strength of the fiber is reduced, the spinnability is reduced, and the difficulty of spinning, needle punching or weaving of the fiber is increased, and the requirements for the performance of production equipment such as spinning, needle punching, weaving, and slitting are also increased. At the same time, the above The improvement of the moisture absorption and gelation speed of the product obtained by the method is also relatively limited, and the problems of slow moisture absorption and slow gelation speed of the product cannot be completely solved.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation method and application of quick absorption saturation gelation seaweed hemostatic dressing
  • Preparation method and application of quick absorption saturation gelation seaweed hemostatic dressing
  • Preparation method and application of quick absorption saturation gelation seaweed hemostatic dressing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Take ethanol and mix it with deionized water at a ratio of 1:3, add NaCl into the solution at a ratio of 1:19 by mass to the alcohol solution, and stir evenly to obtain a salt-containing alcohol solution.

[0028] Take 100 grams of calcium alginate non-woven fabric, soak it in the aqueous solution of salt-containing alcohol, react at room temperature for 40 minutes, take it out and centrifuge to remove the remaining solution.

[0029] Take ethanol and mix it with deionized water at a ratio of 1:3 to obtain an aqueous alcohol solution.

[0030] Rinse the soaked non-woven fabric in alcohol aqueous solution for 5 minutes, take it out and centrifuge to remove the remaining solution, repeat the rinsing and centrifugation operation 3 times, air-dry, cut, package and sterilize the rinsed non-woven fabric to obtain a dressing A1.

Embodiment 2

[0032] Take methanol and mix it with deionized water at a ratio of 6:4, add KCl into the solution at a ratio of 3:97 to the alcohol solution by mass, and stir evenly to obtain a salt-containing alcohol solution.

[0033] Take 100 grams of calcium alginate non-woven fabric, soak it in the aqueous solution of salt-containing alcohol, react at room temperature for 60 minutes, take it out and centrifuge to remove the remaining solution.

[0034] Mix methanol with deionized water at a ratio of 3:7 to obtain an aqueous alcohol solution.

[0035] Rinse the soaked cotton sliver in an alcoholic aqueous solution for 5 minutes, take it out and centrifuge to remove the remaining solution, and repeat the rinsing and centrifugation operation 3 times. Soak the rinsed cotton sliver in methanol solution for dehydration for 1 hour at room temperature, after centrifugation, put it in a vacuum drying oven, keep a vacuum of -0.05MPa at 50°C, and dry for 1 hour.

[0036] The dried tampon is packag...

Embodiment 3

[0038] Mix methanol and ethanol in a ratio of 7:3 to obtain alcohol solution I.

[0039] Take the alcohol solution I and mix it with deionized water at a ratio of 4:6 to obtain the alcohol solution I.

[0040] Get sodium acetate and potassium nitrate to mix according to the ratio of mass ratio 4: 1, join in alcoholic aqueous solution I, stir well, obtain the alcoholic aqueous solution containing monovalent salt, the mass ratio of salt and alcoholic water in the solution is 1: 19.

[0041] Take 100 grams of calcium alginate non-woven fabric, soak it in an aqueous solution of alcohol containing salt, react at room temperature for 30 minutes, take it out and centrifuge to remove the remaining solution.

[0042] Mix methanol and ethanol uniformly in a ratio of 5:5 to obtain alcohol solution II.

[0043] Take the alcohol solution II and mix it with deionized water at a ratio of 9:1 to obtain the alcohol solution II.

[0044] Rinse the soaked non-woven cloth in the alcohol aqueous...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention discloses a preparation method of a quick absorption saturation gelation seaweed hemostatic dressing. The method includes the steps of: soaking, rinsing and drying on calcium fiber textile or non-woven products containing alginate, and the carrying out cutting, packaging and sterilizing to obtain the quick absorption saturation gelation hemostatic dressing. The invention also discloses the application of the quick absorption saturation gelation seaweed hemostatic dressing prepared by the above method. The invention is applicable to rapid absorption and removal of a large amount of surgical diffusate in surgical operation process, so as to realize the effects of rapid hemostasis and operation wound clean; the hemostatic dressing is used for burn, scald and other acute and chronic wounds, can cover the wound and prevent moisture loss in body fluids, provide a positive moist environment for wound healing, prevent the wound from effusion and erosion, isolate bacterial infection, and play the effects of stopping bleeding, relieving pain, promoting wound healing, and reducing scar.

Description

technical field [0001] The invention relates to a method for manufacturing a fast liquid-absorbing gelled seaweed hemostatic dressing, and in addition, the invention also relates to the application of the fast liquid-absorbing gelled seaweed hemostatic dressing. Background technique [0002] At present, absorbable calcium alginate medical dressings have been widely used in clinical wound hemostasis and nursing, and have significant advantages. Calcium alginate dressings are composed of calcium alginate fibers that are woven or needled. When in contact with the wound, ion exchange occurs between the calcium alginate fibers and the sodium ions in the pus, blood or exudate, and the water-insoluble calcium alginate is slowly transformed. It becomes water-soluble sodium alginate, so that a large amount of water enters the interior of the fiber to form a hydrogel, which plays the role of cleaning wound exudate, hemostasis and moist care of the wound. [0003] Hygroscopicity and g...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/42A61L15/44D06M11/13D06L1/12
Inventor 许春晖赵萍
Owner 许春晖
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap