Drug eluting stent capable of reducing late thrombosis
A technology for eluting stents and drugs, applied in the field of intravascular stents, can solve problems such as thrombosis, achieve the effects of reducing thrombosis factors, optimizing hemodynamic environment, and preventing intravascular restenosis
Inactive Publication Date: 2015-02-18
BEIHANG UNIV
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Problems solved by technology
[0003] In order to solve the thrombosis problem of drug-eluting stents, anticoagulant drugs are used clinically after surgery to reduce thrombosis, but it cannot fundamentally solve the problem.
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[0012] Specific embodiments of the present invention are described as follows:
[0013] Such as figure 1 As shown, the drug-coated stent 1 disclosed in the present invention has the shape of a vascular stent, which is composed of two major parts: a stent part and a perforation design part. The stent part can be a metal stent or a degradable stent, and its weaving method or shape can adopt the weaving method or shape of the previously disclosed vascular stent.
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An intravascular stent is an effective interventional device for treating cardiovascular hemadostenosis or blockage, and a drug eluting stent is taken as a stent of newest generation, so that the restenosis rate after stent implantation is remarkably reduced, and thus the occurrence rate of stent thrombosis is increased. The reasons are as follows: firstly, a coating medicine of the stent is capable of inhibiting regeneration of vascular smooth muscle and growth of endothelial cells, so that endothelialization of a vascular wall is incomplete and a cell matrix is exposed, and thus blood clotting response is promoted; after stent implantation, regional blood disorder is caused, so that blood clotting response is further promoted, and thus stent thrombosis is caused and a blood vessel in the stent generates restenosis. The drug eluting stent aims at the problems and provides a new intravascular stent provided with perforated design, so that the local turbulence in the stent is reduced and the occurrence rate of thrombus in the blood vessel is reduced under the condition that the strength of the stent is guaranteed, and thus restenosis in the blood vessel is prevented.
Description
technical field [0001] The invention relates to an intravascular stent, in particular to a drug-eluting stent. Background technique [0002] The incidence of cardiovascular diseases such as coronary artery disease caused by atherosclerosis is increasing, and it has become one of the diseases that seriously endanger human health. At present, the main means of treating this disease is to dilate and recanalize narrowed and occluded blood vessels through interventional stent implantation technology. The stent, as a tubular object supporting the blood vessel, completely solves the restenosis caused by the elastic recoil of the blood vessel after the operation, and significantly reduces the restenosis rate after the operation by about 20% to 30%. In addition, it also has the advantages of high curative effect, less trauma, low risk, fewer complications, and shorter hospital stay. It is currently the first choice for the treatment of such diseases. The stimulation of blood vessel...
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Inventor 薛燕刘肖孙安强任长辉邓小燕樊瑜波
Owner BEIHANG UNIV
