18F labeling PET/CT molecular imaging probe rapid drying and activation device

Abstract

The invention relates to an 18F labeling PET / CT molecular imaging probe rapid drying and activation device and belongs to the nuclear medicine and molecular imaging field. The 18F labeling PET / CT molecular imaging probe rapid drying and activation device is formed by a first microfluidic chip, a second microfluidic chip, a third microfluidic chip and a fourth microfluidic chip; the first microfluidic chip is a main reaction heating chip; the second microfluidic chip is an anhydrous solution injection chip; the third microfluidic chip is an aqueous solution injection chip; the fourth microfluidic chip is an 18F labeling PET / CT molecular imaging probe take-out chip; the 18F labeling PET / CT molecular imaging probe rapid drying and activation device can be manufactured into an 18F ion which comprises 18F-FDG, 18F-FLT, 18F-FHBG and the like through drying and activation. According to the 18F labeling PET / CT molecular imaging probe rapid drying and activation device, the structure is simple, a reagent is saved, the response is rapid, and a precursor of a required marker can be quantitatively dried and activated according to needs of patients.

Description

technical field [0001] The present invention relates to a 18 An F-labeled PET / CT molecular imaging probe fast drying and activating device belongs to the field of nuclear medicine and molecular imaging. Background technique [0002] Molecular imaging is the frontier research field of biomedicine. It uses three-dimensional images at the molecular, cellular and subcellular levels to directly observe the biochemical changes, performance, characteristics and quantification in vivo related to the growth and development of organisms and the occurrence and development of diseases. [0003] PET / CT molecular imaging probes are various positron nuclides ( 18 F, 15 O, 13 N, 13 C, 124 I, 76 Br, 64 Cu)-labeled small chemical compounds or biomolecules, such as in cancer disease examination, are used 18 F-labeled compounds were used as probes. Its main feature is that it is radioactive and requires radiation protection. Therefore, its production is completely dependent on the au...

AI Technical Summary

Problems solved by technology

[0005] However, now 18 F Molecular imaging probe drying and activation technology has the following disadvantages: (1) It requires a huge system to complete the drying and activation process; (2) The drying and activation process requires more reagents; (3) It takes a long time; (4) It cannot be precisely controlled The amount of reagent used will cause waste in the later synthesis

(5) It is impossible to dry and activate the food for multiple people according to the weight of a single person 18 F complex; (6) activated by one drying 18 F complex can only be used as a molecular probe

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