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Active halogen antimicrobial composition and method of use

一种抗微生物、组合物的技术，应用在植物学设备和方法、应用、杀生剂等方向，能够解决有害气味等问题

Inactive Publication Date: 2015-03-04
LONZA INC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, chlorine bleach and peracetic acid compositions have significant environmental and disposal disadvantages, more notably but not limited to a strong odor that is considered harmful to most people

Method used

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  • Active halogen antimicrobial composition and method of use
  • Active halogen antimicrobial composition and method of use
  • Active halogen antimicrobial composition and method of use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055]The effect of pH reduction on the activity of a stabilized bromine solution against the spore form of Clostridium difficile (ATCC 43598) was determined using the EPA standard quantity plate carrier test method at 20°C, 10 minutes contact time. Effective sporicides provide a greater than 6 log reduction in spore concentration.

[0056] As shown in Table 1, dilute the received stable bromine solution to a concentration of 5000-12000 ppm total active halogen, such as Cl 2 , resulting in an ineffectively high pH > 12 solution. 20 is a stable bromine-containing solution having a pH of about 13 and containing about 14% active bromine and is available from Nalco, whose office is at 1601 W. Diehl Road, Naperville, IL 60563-1198. 7.1 is a stable bromine-containing solution containing sulfamic acid and sodium hydroxide, having a pH of about 13 and containing about 16% active bromine, prepared according to U.S. Patents 7,045,153 and 7,455,859, which are hereby incorporated by re...

Embodiment 2

[0062] The effect of pH reduction at 20°C with a 10 minute contact time on the activity of two types of stabilized bromine solutions against the spore form of Clostridium difficile (ATCC 43598) was determined using the EPA standard quantity plate carrier test. Effective sporicides provide a greater than 6 log reduction in spore concentration.

[0063] As shown in Table 2, at reduced pH with Solutions were all reduced by >6 logs. This suggests that a variety of stable bromine sources can achieve a pH-lowering effect that enhances potency.

[0064] Table 2. Effect of pH Change on Potency of Stabilized Bromine Solutions

[0065]

Embodiment 3

[0067] The stability of diluted solutions of stabilized bromine with and without acid addition was determined by diluting the stabilized active bromine products shown in Table 3 to a theoretical concentration of approximately 6000 ppm total active halogen, stored at 20°C and measured as a function of time The total active halogen concentration and pH. Using the standard DPD method to measure Cl 2 Reported total active halogen concentration.

[0068] Table 3. Stability Test Formulations

[0069]

[0070] It is expected that the solution is stable for a minimum of 1 hour when used immediately after dilution, and a minimum of 1 day for industrial applications, or up to 1 week for institutional applications. As shown in Table 4, the acidified dilutions provided sufficient stability for practical use, as >80% active halogen was retained even after 7 days. As shown in Table 5, the acidified solution not only retained high levels of active halogen, but it also maintained a low ...

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PUM

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Abstract

Disclosed is an antimicrobial composition containing an active halogen-containing component having a source of an active halogen and having an elevated pH, which is mixed with an acidic component. An acidic component is added in an amount to the active halogen-containing component to reduce the pH of the antimicrobial composition. When the pH of the active halogen-containing composition is reduced, the resulting composition has been discovered to be effective as a disinfectant and, particularly, as a sporicide. Application methods for applying the composition are also described.

Description

technical field [0001] The present invention relates to antimicrobial compositions effective for decontaminating surfaces, delivery methods for applying the antimicrobial compositions to surfaces, and methods for decontaminating those surfaces. Background technique [0002] Antimicrobial compositions for decontamination, disinfection and / or cleaning must have an effective microbiocide rate to be suitable for use as decontamination, disinfection and / or cleaning compositions. These antimicrobial compositions are generally expected to be low corrosive to the surface being treated and low in odor. Furthermore, these compositions will generally contain only enough microbial control agent to be effective for the intended application. Having too much microbial control agent provides no benefit to the resulting composition and any excess microbial control agent in the composition is essentially wasted. Too low a level of microbial control agent will render the composition less eff...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N25/18A01N59/00
CPCA01N59/00A01N25/00A01N25/22A01N2300/00
Inventor 约瑟夫·凯米拉史蒂文·J·科尔比菲利普·高登·斯威尼
Owner LONZA INC
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