Clinical diagnostic system including instrument and cartridge
A diagnostic system and material box technology, which is applied in the field of clinical diagnostic systems including instruments and material boxes, can solve problems such as inaccurate diagnosis, achieve the effect of reducing total cost and increasing reliability
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example 1
[0528] Example 1 – Calculate the volume of a liquid
[0529] Figure 29 A typical output of a system for monitoring a fluid channel through which a volume of liquid passes is illustrated. exist Figure 29 , the horizontal axis is time (each data point is 10 milliseconds (ms)), and the vertical axis is the analog sensor output in volts. There is a 130mV difference between high (representing air in the system) and low (representing liquid) in the system. There is a 110 mV difference between low (representing liquid) and high (after data point 342, representing moisture). The noise level of the signal is about 47mV, which is low enough to enable a clear distinction between air and liquid in the channel.
[0530] Use the sensor output to calculate the volume of the liquid by counting how long the liquid has been present and multiplying by the pump's flow rate during the fluid movement. Also, the fact that there are no interruptions in the "low" signal (eg, remains low, not ...
example 2
[0531] Example 2 – Detect leaks in fluid systems
[0532] Figure 30A An example of a sequence of operations for detecting a leak in a fluid system is illustrated. On single-use cartridges, the patient sample is divided into aliquots of equal size and each aliquot is processed independently in a multi-test cartridge (cartridge capable of running multiple tests with the same patient sample). The sample Vs is drawn into the channel via the probe at probe entry site 716 . The sample volume is drawn into the desired channel through the probe at the probe entry site 716 , which is sealed against the septum 350 . The software resets the timer (T0) and commands the pump to pump at a fixed flow rate (Fr) while monitoring the output of the optical sensor until a gas-liquid boundary ( Figure 30B ), once this boundary is detected, the firmware backs up the current timer (T1).
[0533] The pump continues to draw the sample, and once a liquid-gas transition is detected, the software...
example 3
[0537] Example 3 - Detection of cartridges stored at different temperatures and applying different hold temperature setpoints for cartridges stored at different temperatures.
[0538] Cartridges stored at two different temperatures were differentiated by monitoring the temperature with a temperature sensor and estimating the temperature loss for the first 30 seconds of cartridge processing. Figure 47 is a graphical representation of the temperature monitored with the temperature sensor for two different cartridges stored at two different temperatures. The instrument is able to apply different holding parameter values when two cartridges in different storage conditions are detected.
[0539] Table 4 below shows the scenario when different keep warm set temperatures are applied to cartridges stored at two different storage temperatures. Table 4 below shows the set temperatures for this example.
[0540]
[0541] Note that for Test A, both cartridges stored at 15°C and ...
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