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Cecropin antibacterial peptide fermentation sterilization equipment and sterilization method thereof

A technology of cecropin antimicrobial peptide and sterilization equipment, which is applied in heating and other directions, can solve the problems of loud noise and vibration, and achieve the effects of reducing noise and vibration, saving electric energy and reducing impact

Active Publication Date: 2015-04-15
LINZHOU SINAGRI YINGTAI BIOLOGICAL PEPTIDES CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention aims at the above-mentioned problem of huge noise and vibration during the sterilization of the existing material liquid, and provides a cecropin antimicrobial peptide fermentation and sterilization equipment and a sterilization method thereof, which will not produce strong noise and vibration during sterilization, and protect the equipment

Method used

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  • Cecropin antibacterial peptide fermentation sterilization equipment and sterilization method thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0021] Sterilization Method Example 1: A method for sterilizing cecropin antibacterial peptide by using the above-mentioned sterilization equipment, including the following steps:

[0022] (1) Air and steam sterilization: After the material liquid enters the sterilization tank, the air pipe is connected with the air compressor, and the steam pipe connected with the air pipe enters steam and air at the same time, and the steam intake is 600 m 3 / Hour, air intake is 200m 3 / Hour; the other two steam pipes have a single steam inlet, with a steam inlet of 800 m 3 / Hour, the steam temperature is 135℃-145℃, it can be 135℃, 138℃, 140℃, 143℃ or 150℃, that is, the steam temperature can be any value between 135℃-145℃, and the stirrer is turned on for stirring ;

[0023] (2) When the temperature of the material liquid is heated to 90℃, stop the air intake, because after 90℃, the difference between the temperature of the material liquid and the steam temperature is relatively small, and there w...

Embodiment 2

[0026] Sterilization Method Example 2: A method for fermentation and sterilization of cecropin antibacterial peptide using the above-mentioned sterilization equipment, including the following steps:

[0027] (1) Air and steam sterilization: After the material liquid enters the sterilization tank, the steam pipe connected with the air pipe enters steam and air at the same time, and the steam intake is 550m 3 / Hour, the air intake is 150m 3 / Hour; the other two steam pipes have single steam inlet, and the steam inlet is 750 m 3 / Hour, the steam temperature is 135℃, while stirring;

[0028] (2) When the temperature of the material liquid is heated to 85℃, stop the air intake;

[0029] (3) When the temperature of the material liquid is heated to 105℃, stop stirring;

[0030] (4) Heat the material liquid to 115°C and disinfect for 25 minutes.

Embodiment 3

[0031] Sterilization method Example 3: A method for fermentation and sterilization of cecropin antimicrobial peptide using the above-mentioned sterilization equipment, including the following steps:

[0032] (1) Air and steam sterilization: After the material liquid enters the sterilization tank, the steam pipe connected with the air pipe enters steam and air at the same time, and the steam intake is 650 m 3 / Hour, the air intake is 250m 3 / Hour; the other two steam pipes have single steam inlet, and the steam inlet is 850 m 3 / Hour, steam temperature is 145℃, while stirring;

[0033] (2) When the temperature of the material liquid is heated to 95℃, stop air intake;

[0034] (3) When the temperature of the material liquid is heated to 115℃, stop stirring;

[0035] (4) Heat the material liquid to 125°C and sterilize it for 35 minutes.

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Abstract

The invention provides cecropin antibacterial peptide fermentation sterilization equipment and a sterilization method thereof. The equipment includes a sterilization tank and a stirrer mounted in the sterilization tank, three steam pipelines are disposed at the bottom of the sterilization tank, and one of the steam pipelines is connected to an air pipeline. The invention also includes a sterilization method. According to the invention, one steam pipeline is provided with the air pipeline so that air can enter at the same time, steam and air are fed simultaneously, air makes the steam disperse rapidly, a feed liquid can be heated evenly, sound and vibration can be reduced to avoid device damage, and also influence to the work environment is reduced. According to the invention, when the feed liquid is heated to 110DEG C, stirring can be stopped, and electric energy is saved.

Description

Technical field [0001] The invention relates to the field of biological fermentation, in particular to a cecropin antibacterial peptide fermentation and sterilization equipment and a sterilization method thereof. Background technique [0002] Cecropin antimicrobial peptide is the first animal antimicrobial peptide to be discovered. In 1980, it was isolated from the chrysalis pupae of Boman et al. Most of these active peptides have the characteristics of strong alkalinity, thermal stability and broad-spectrum antibacterial. Antimicrobial peptides have a strong killing effect on bacteria, especially their killing effect on certain drug-resistant pathogens. Pay attention. [0003] At present, when the antimicrobial peptide is fermented and sterilized, high-temperature steam is directly passed into the sterilization tank for sterilization. At the beginning, the material liquid temperature is relatively low, the steam temperature is high, and the temperature difference is relatively la...

Claims

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Application Information

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IPC IPC(8): A61L2/07
Inventor 胡国春郭文江赵福生
Owner LINZHOU SINAGRI YINGTAI BIOLOGICAL PEPTIDES CO LTD