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Respiratory gas analysis device

An analysis device and breathing gas technology, applied in the field of medical detection and analysis, can solve the problems of inability to realize online analysis, instability of the test system, influence of accuracy, etc., and achieve the advantages of large-scale popularization and application, low production cost, and good reproducibility. Effect

Inactive Publication Date: 2015-04-15
SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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Problems solved by technology

[0003] In the prior art, the devices used for respiratory gas analysis mostly adopt the GC-MS (gas phase-mass spectrometry) method, which uses GC technology to realize sample separation and collection, and then uses MS technology for qualitative or quantitative analysis, but This method is time-consuming and cannot be analyzed online
In addition, a small number of gas analysis devices use sensor technology, but this technology is also prone to limit drift, which affects accuracy and leads to instability of the test system

Method used

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Embodiment Construction

[0028] The present invention will be further described in detail below in conjunction with the accompanying drawings, so that those skilled in the art can implement it with reference to the description.

[0029] In the diagnosis of modern medical diseases, it is believed that acetone is a molecular marker for diagnosing diabetes, nitric oxide is a molecular marker for diagnosing bronchial diseases, and cyclic hydrocarbons are molecular markers for diagnosing cancer. When a patient suffers from these diseases, the content of corresponding molecular markers in the breath gas will increase significantly, that is, it is assumed that the content of acetone in the breath exhaled by a diabetic patient will be much higher than that of normal people. According to this feature, A device for qualitative and quantitative detection of these special molecular markers can be developed and designed, so as to achieve the purpose of rapid, painless and non-invasive diagnosis.

[0030] This case...

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Abstract

The invention discloses a respiratory gas analysis device including a laser, a flight tube, a photoelectric detector, a piezoelectric synchronous trigger, a gas inlet, a vacuum pump and a controller, wherein the flight tube is internally provided with a first annular electrode, a second annular electrode and a third annular electrode at intervals, a region between the first annular electrode and the second annular electrode is a reversed electric field region, and a region between the second annular electrode and the third annular electrode is a forward electric field region. A laser ionization flight time mass spectrometry method is used for real-time on-line analysis of samples, and has the advantages of short analysis time, large detectable molecular weight, high sensitivity for analysis, good reproducibility of detection results, and stable performance; the device has the advantages of simple structure, low production cost, no any trauma to detected patients, and is conducive to large-scale popularization and application.

Description

technical field [0001] The invention relates to the field of medical detection and analysis, in particular to a clinical respiratory gas analysis device. Background technique [0002] At present, diagnosing diseases by analyzing certain specific components in blood has become a routine means of modern medical diagnosis. The metabolites in the blood enter the lungs through the gas-blood barrier, causing changes in the composition of the exhaled gas, which increases the concentration of some specific gases excreted from the body. Therefore, compared with blood analysis, respiratory gas analysis has similar functions. sex, but also non-invasive. The key to realizing respiratory gas analysis is how to realize the detection of low trace gases in respiratory gas. [0003] In the prior art, the devices used for respiratory gas analysis mostly adopt the GC-MS (gas phase-mass spectrometry) method, which uses GC technology to realize sample separation and collection, and then uses M...

Claims

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Application Information

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IPC IPC(8): G01N15/10G01N21/64
Inventor 姜琛昱张运海
Owner SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
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