Unlock instant, AI-driven research and patent intelligence for your innovation.

Application of basilisk in the preparation of drugs for the treatment of alcohol dependence

A technology of alcohol dependence and Budismoside, applied in the field of medicine, can solve problems such as no activity of Budismoside

Active Publication Date: 2015-09-09
HEILONGJIANG UNIV OF CHINESE MEDICINE
View PDF6 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] There are no reports about the use of basilisk in the treatment of alcohol dependence in domestic and foreign literatures, and there are no related reports on the activity of basilisk on receptors and targets related to alcohol dependence

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of basilisk in the preparation of drugs for the treatment of alcohol dependence

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Example 1 Preparation of Mimenghuaside Tablets

[0023] Budismoside 10g

[0024] Microcrystalline Cellulose 100g

[0025] Magnesium Stearate 30g

[0026] Micronized silica gel 10g

[0027] The preparation method: mix the raw materials of vermicelli and microcrystalline cellulose, pass through a 100-mesh sieve, add magnesium stearate and micro-powder silica gel, stir evenly, and press into tablets to obtain.

Embodiment 2

[0028] Example 2 Preparation of Oral Liquid Preparation of Budismanthin

[0029] Budismoside 10g

[0030] Sodium bicarbonate 1g

[0031] Water for injection 100ml

[0032] Preparation method: Add sodium bicarbonate and saponin into water for injection in turn, and mix well to obtain.

Embodiment 3

[0033] The preparation of the capsule of embodiment 3 Budismoside

[0034] Budismoside 10g

[0035] Magnesium Stearate 30g

[0036] Micronized silica gel 10g

[0037] Gum Arabic 20g

[0038] Carboxymethyl starch 10g

[0039] Preparation method: Mix the above ingredients evenly, granulate by dry method, and fill into capsules.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses novel application of tiliroside, that is, application of tiliroside in preparing a medicine for alcohol dependence. The experiment result shows that tiliroside has a remarkable abstinence function on alcohol dependence, and is high in safety. When being orally taken, the medicine can take a remarkable curative effect into play, so that an oral medicine dosage form can be prepared, and the medicine has the advantage of being convenient to carry over for a patient. As the alcohol dependence is not abstained through gastrointestinal tract stimulus response in an emetic manner when the medicine is used, relatively small pain experience can be caused for the patient.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to the application of saponin in the preparation of drugs for the treatment of alcohol dependence. Background technique [0002] Alcohol is another common addictive substance besides opioids and psychostimulants (cocaine, etc.). Alcohol dependence is a chronic, relapsing disorder characterized by uncontrolled alcohol consumption, which can occur continuously or periodically. [0003] Alcohol has become a substance that is commonly abused worldwide. At present, the number of deaths caused by alcohol-induced diseases in the United States is 100,000 people every year, and 8.1 million people suffer from alcohol addiction. The annual cost of treatment for alcohol dependence in Europe is as high as 0.68% to 0.95% of the gross domestic product, which has become a heavy economic burden on the social health care system. One out of every 65 families in my country suffers from alcohol de...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61P25/32
CPCA61K9/0053A61K9/08A61K9/1652A61K9/2054A61K31/7048A61K47/02
Inventor 佟欣郑南
Owner HEILONGJIANG UNIV OF CHINESE MEDICINE