Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Drug for treating femoral head necrosis according to pathology

A technology for necrosis of the femoral head and drugs, applied in drug combinations, bone diseases, pharmaceutical formulations, etc., can solve the problems of subchondral fractures aggravating the degree of collapse, patients' lifelong disability, and sequestrum cannot repair and regenerate by themselves, and achieve good results. , the effect of a reasonable composition

Inactive Publication Date: 2015-04-29
王海燕
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] ②The repair tissue is relatively fragile, unable to bear the weight of the human body and collapses, and subchondral fractures aggravate the degree of collapse;
[0020] For femoral head necrosis, orthopedics at home and abroad often use methods such as drilling decompression, vascular grafting, free bone grafting, osteotomy, and artificial joint replacement. Because the sequestrum cannot be repaired and regenerated by itself after surgical treatment, it will cause lifelong damage to the patient. disabled

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Drug for treating femoral head necrosis according to pathology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Using deer title grass, thousand years of health, soap thorns, touguxiao, safflower, knotweed, solitary, Yuanhu, drynaria, sea wind rattan, pheasant grass, two-finger sword, mugwort leaves, scorpion, big thistle, elderberry, horsewhip Grass, summer no, Cistanche deserticola are prepared as raw materials. Its components (% by weight) per pair are Lubiancao 8.1, Qiannianjian 6.3, Zaoci 8.2, Touguxiao 7.8, Honghua 6.9, Polygonum cuspidatum 2.9, Duhuo 7.4, Yuanhu 4.9, Drynaria 2.2, and Caulis 2.7 , pheasant grass 7.6, two-finger sword 4.7, mugwort 3.1, sage 3.6, thistle 5.1, elderberry 5.6, verbena 5.2, summer 3.3, cistanche 4.4. Take the above-mentioned 19 raw materials with a total weight of 234 grams, add about 1200ml of water to soak for 3-4 hours, boil with strong fire, simmer for 50-60 minutes, remove the dregs to get about 220ml of medicinal juice, add about 300-350ml of water to the dregs, Boil for another 30-35 minutes, remove the slag to obtain about 80ml of filt...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to the field of a traditional Chinese medicine formula, and particularly relates to a drug for treating femoral head necrosis according to pathology. The drug is characterized by being prepared from the following active pharmaceutical ingredients in percentage by weight: 5-9% of herba pyrolae, 4-7% of rhizoma homalomenae, 6-9% of spina gleditsiae, 5-8% of ganltheria forrestii diels, 5-8% of flos carthami, 2-4% of rhizoma polygoni cuspidati, 6-8% of radix angelicae pubescentis, 4-6% of rhizoma corydalis, 2-3% of rhizoma drynariae, 2-3% of caulis piperis kadsurae, 6-9% of hypoxis aurea lour., 4-6% of turpinia arguta seen, 2-4% of folium artemisiae argyi, 3-5% of rhizoma dioscoreae hypoglaucae, 4-6% of herba seu radix cirsii japonici, 4-7% of sambucus l., 4-6% of herba verbenae, 2-4% of rhizoma corydalis decumbentis, and 4-6% of herba cistanches, all of which are soaked with water and decocted and then deslagged to obtain filtrate. The drug is reasonable in formula, free from side effects, and good in efficacy for treating the femoral head necrosis.

Description

technical field [0001] The invention relates to a Chinese patent medicine preparation, in particular to a medicine for treating femoral head necrosis according to pathology. Background technique [0002] As we all know, the occurrence of femoral head necrosis is a gradual process. Clinically, femoral head necrosis is divided into I, II, III, and IV stages. In different stages, the length of ischemic time and other pathological factors cause different damage to the femoral head. The following four stages of femoral head necrosis illustrate the entire pathological evolution process of the femoral head from the initial ischemia to necrosis and finally collapse. [0003] Stage I femoral head necrosis: [0004] ①Six hours after bone ischemia, hematopoietic cells in the medullary cavity began to die; [0005] ② About 6 to 12 hours after blood flow is interrupted, hematopoietic cells die first; [0006] ③ After 12 to 48 hours, the bone cells and osteoblasts die; [0007] ④ Afte...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P19/08
Inventor 王海燕杨宪鲁
Owner 王海燕
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products