CDKN2A epitope peptide for detecting cervical cancer markers and application of CDKN2A epitope peptide

An antigenic epitope, cervical cancer technology, applied in animal/human peptides, tumor-specific antigens, tumor rejection antigen precursors, etc., can solve problems such as low sensitivity and poor specificity
CN104558147AActive Publication Date: 2015-04-29ๅˆ˜ๆž—ๆž—
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
ๅˆ˜ๆž—ๆž—
Publication Date
2015-04-29

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Abstract

The invention relates to a CDKN2A epitope peptide for detecting cervical cancer markers and an application of the CDKN2A epitope peptide, and belongs to the technical field of biology. An amino acid sequence of the CDKN2A epitope peptide for detecting the cervical cancer markers is as shown in SEQ ID NO:1; and the CDKN2A epitope peptide for detecting the cervical cancer markers is applied to preparation of an early diagnosis kit for cervical cancer. The CDKN2A epitope peptide has the advantages that the autoantibody expression level in serum and plasma of a patient with the cervical cancer is detected and a corresponding reagent is developed; the dangerousness of the cervical cancer is predicted; and a foundation is laid for preparation of the early diagnosis kit for the cervical cancer.
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Description

technical field

[0001] The invention belongs to the field of biotechnology, and specifically relates to a CDKN2A polypeptide fragment with detection cervical cancer markers screened by bioinformatics simulation. Population epidemiological detection has verified its detection sensitivity and specificity, and is further used for the preparation of cervical cancer Early diagnostic kits lay the groundwork. Background technique

[0002] A large number of studies have shown that tumor-associated antigens in serum or plasma can induce the body to produce autoantibodies, and there are both tumor antigens and autoantibodies against the tumor antigens in the serum of cancer patients. Therefore, both antibodies can be used to detect tumor antigens, and antigens can also be used to detect tumor antigen autoantibodies, but the specificity and sensitivity of using tumor autoantibodies to detect tumors are much higher than using tumor antigens to detect tumors. Many tumor-associated antig...

Claims

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