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Design method of high-performance micro gene sequencing and automatic analysis device

An automatic analysis and gene sequencing technology, applied in computing, special data processing applications, instruments, etc., to achieve fast computing speed, fast and efficient sequencing, and fast sequencing

Inactive Publication Date: 2015-04-29
LANGCHAO ELECTRONIC INFORMATION IND CO LTD
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Such a set of processes is highly technically dependent

Method used

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  • Design method of high-performance micro gene sequencing and automatic analysis device

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Embodiment Construction

[0013] In order to make the purpose, technical solutions and advantages of the present invention clearer, the content of the present invention is described in more detail below:

[0014] 1) Determine the sequencing platform: choose a MinIon sequencer with small size, long sequencing read length, fast speed, and low cost. After loading the sample, it can be directly inserted into the server’s USB port and directly connected to the server to complete the sequencing quickly;

[0015] 2) Determination of the computing platform: The computing platform is a desktop server with low noise. In addition, considering the large memory required for splicing calculations, the computing platform is configured with 128GB of memory, 10TB of storage space, and a haswell processor;

[0016] 3) Server system deployment: configure the operating system, basic environment, compiler, etc.;

[0017] 4) galaxy deployment: download the source package of galaxy, install the basic framework, configure htt...

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Abstract

The invention provides a design method of a high-performance micro gene sequencing and automatic analysis device, and relates to the technical field of gene sequencing. The high-performance micro gene sequencing and automatic analysis device mainly comprises a miniature sequencer, a desktop server and an automatic data analysis system, wherein a MinIon sequencer is selected as the miniature sequencer; the desktop server with small noise and large storage space is selected; an automatic data analysis system is provided with a galaxy analysis platform; the galaxy provides a frame platform for data analysis; common bioinformatic software and a data set are configured on the platform for people; the flow can be constructed; and automatic operation by a user is facilitated.

Description

technical field [0001] The invention relates to gene sequencing technology, in particular to a high-performance miniature gene sequencing and a design method of an automatic analysis device. Background technique [0002] It's been nearly a decade since Harvard geneticist George Church and 454 Life Sciences company Jonathan Rothberg started the next-generation sequencing (NGS) revolution. Sequencers have also undergone earth-shaking changes, with continuous improvement in terms of throughput, sequencing accuracy, sequencing cycle, and read length, and their applications are becoming more and more extensive. For example, more and more researchers use sequencing methods for tumor research, or identify potential drug targets through exome sequencing. When diagnosing genetic diseases in children, people have gradually abandoned traditional diagnostic methods and turned to whole exome sequencing. Sequencing currently used in clinical or research basically still uses large-scale ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/20
Inventor 金莲
Owner LANGCHAO ELECTRONIC INFORMATION IND CO LTD
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