Absorbable luminal stent and preparation method thereof

An absorption tube and absorption polymer technology, applied in the field of medical devices, can solve the problems of necrosis, stent stenosis, smooth muscle cell proliferation, etc., to reduce damage, ensure mechanical properties, and improve the duration of radial support force.

Active Publication Date: 2015-05-27
SHANGHAI BIO HEART BIOLOGICAL TECHNOLOGY CO LTD +1
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  • Abstract
  • Description
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Problems solved by technology

However, these improved methods all have a step in which the stent needs to be heated after being implanted in the blood vessel. Because the stent is in contact with the vessel wall, heating the stent in the body is likely to cause damage and necrosis of the arterial wall, and the ensuing complications are Smooth muscle cell proliferation leading to in-stent restenosis

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  • Absorbable luminal stent and preparation method thereof
  • Absorbable luminal stent and preparation method thereof
  • Absorbable luminal stent and preparation method thereof

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[0039] In order to make the technical problems, technical solutions and advantages to be solved by the present invention clearer, preferred solutions of the present invention will be described below in conjunction with examples. These descriptions only illustrate the features and advantages of the present invention, but do not limit the protection scope of the present invention.

[0040] Aiming at the impact on the mechanical properties of the polymer stent after implantation caused by damage to the stress concentration area due to the two necessary processes of crimping and stretching in the prior art, and the disadvantages of heating in the body to reduce damage , the present invention proposes an absorbable luminal stent and a preparation method thereof, by preparing a through hole on the stress concentration area when the stent body is crimped and / or stretched, that is, at the crest of the first V-shaped bar and the first V-shaped bar. A plurality of through holes are prep...

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Abstract

The invention provides an absorbable luminal stent and a preparation method thereof. The absorbable luminal stent comprises a stent body, a plurality of through holes prepared on the stent body and bioresorbable polymer materials full filled in the through holes. When the stent is transplanted into a blood vessel, by compounding of the materials in the through holes and the material of the stent body, damage caused in the pressure holding and opening process of the stent is reduced, duration time of a radial supporting force of the stent is prolonged and mechanical performance of the transplanted stent is ensured.

Description

technical field [0001] The invention relates to the field of medical devices, in particular to an absorbable lumen stent and a preparation method thereof. Background technique [0002] Since German doctor Andrea Gronzgo first proposed the idea of ​​stents in 1976, and since coronary stents were widely used clinically in the 1990s, the third generation of absorbable drug-eluting stents has appeared. However, at present, a certain proportion of patients with drug-eluting stents (DES) based on stainless steel and cobalt-chromium alloys still have subacute thrombosis and restenosis after stent implantation, and these metal stents are permanently retained. internally. Thus, bioabsorbable scaffolds (BVS) began to become the focus and focus of attention. [0003] Absorbable stents have multiple possible benefits in theory: after the stent is absorbed, the normal contractility of blood vessels can be restored, preventing the occurrence of vascular restenosis; the vascular dynamics...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/90A61L31/06A61L31/14
CPCB29L2031/7543B29C49/04B29C2791/009A61F2/915A61F2002/91575A61F2250/003A61F2250/0068A61F2210/0004A61F2240/001B29C70/745A61F2230/0069B29K2995/006B29K2105/258B29L2031/7534A61F2250/0059A61F2230/0017A61F2230/0006A61F2230/0008A61F2/91A61F2250/0015A61F2002/91558A61F2002/91566
Inventor 盛卫文张瑞岩
Owner SHANGHAI BIO HEART BIOLOGICAL TECHNOLOGY CO LTD
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