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Fixing hold-down device for PDMS micro flow cell

A technology of fixing pressing device and micro-flow, applied in measuring devices, instruments, scientific instruments, etc., can solve the problems of PDMS micro-flow cell damage, inability to achieve digital quantification control, shortening the service life of flow cell, etc. Good tightening effect, simple structure, and the effect of avoiding damage

Active Publication Date: 2015-07-15
浙江诺迦生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] There are certain defects in this method. One is that every time the screw (fixing bolt) is adjusted, it can be known whether it is screwed to the appropriate position and the current position at this time by checking the liquid outlet of the liquid outlet and whether the flow cell is leaking. Whether the pressing force is suitable or not is mainly judged by the operator based on experience, and digital quantitative control cannot be achieved, and the adjustment efficiency is low and the effect is poor; the second is that unnecessary adjustment of the screw position during use will cause damage to the PDMS micro flow cell itself. Thereby shortening the service life of the flow cell and increasing the cost of the experiment

Method used

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  • Fixing hold-down device for PDMS micro flow cell
  • Fixing hold-down device for PDMS micro flow cell
  • Fixing hold-down device for PDMS micro flow cell

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Such as figure 1 , 2 Shown in and 4, the fixed pressing device for the PDMS micro-flow cell of the present embodiment comprises: workbench 1, is installed on the workbench 1 and is used to carry the base 2 of PDMS micro-flow cell, is installed on this workbench and Across the support frame 3 of the base 2, the top of the support frame 3 is vertically equipped with a spiral micrometer head 4, and the micrometer screw rod 41 of the spiral micrometer head 4 is used as a pressure rod, and its end passes through the top of the support frame 3 towards the base 2 .

[0034] A chute 11 for slidingly installing the base 2 is provided on the workbench 1 , and a clamping screw 12 for locking the base 2 is installed on the chute 11 .

[0035] The bracket frame 3 includes: two sets of upright poles 31, fixed on the workbench 1, respectively located on both sides of the base 2; glands 32, one side of which is hinged on the top of one set of upright poles, and the opposite side pas...

Embodiment 2

[0042] Such as Figure 5 As shown, in this embodiment, except that the installation method of the bracket frame and the screw micrometer head, and the cooperation method of the pressure plate and the micrometer screw are different from the embodiment 1, the rest of the structure is the same as the embodiment 1.

[0043] Two symmetrically arranged rails 7 are arranged on the workbench 1, and the bottom ends of each set of vertical rods 31 are slidably installed in the corresponding rails 7;

[0044] The slideway 8 of the vertical track 7 is arranged on the gland 32 , and the mounting section 42 of the screw micrometer 4 is slidably installed in the slideway 8 .

[0045] A tapered alignment hole 52 is provided at the center of the top surface of the pressing plate 5 , and the end of the micrometer screw 41 is tapered to match the alignment hole 52 .

[0046] Before pressing, adjust the screw micrometer head 4 to the center position of the pressure plate by moving the bracket fr...

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PUM

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Abstract

The invention discloses a fixing hold-down device for a PDMS micro flow cell. The fixing hold-down device comprises a worktable, a base mounted on the worktable and used for bearing the PDMS micro flow cell, and a support frame mounted on the worktable and crossing the base; a spiral micrometer head is vertically mounted at the top of the support frame; the micrometric screw of the spiral micrometer head serves as a compression bar, and the tail end of the compression bar penetrates through the top of the support frame and faces the base. According to the fixing hold-down device for the PDMS micro flow cell, as the spiral micrometer head serves as a device for regulating hold-down force of the PDMS micro flow cell and the base, the pressure can be controlled by use of scale marks on the spiral micrometer head when the flow cell is fixed, and the appropriate position can be adjusted quickly; as a result, the times of operation are reduced, the operation efficiency is improved, and meanwhile, the damage to the flow cell due to multiple adjustment is avoided.

Description

technical field [0001] The invention relates to a compression device, in particular to a fixed compression device for a PDMS micro flow cell. Background technique [0002] Polydimethylsiloxane (Polydimethylsiloxane, PDMS) is commonly known as silicone rubber. With its low cost, good chemical inertness, good adhesion to silicon wafers, metal sheets, and glass sheets, and the ability to carry out various In recent years, it has been widely used in the fields of microfluidics and other fields. [0003] Such as image 3 As shown, the PDMS micro-flow cell 6 includes: a base plate 61 and a PDMS module 62 fixed on the base plate. In the figure, the PDMS module 62 faces upwards. In actual use, it is generally installed downwards, and the base plate 61 is provided with a liquid inlet. 63, liquid outlet 64 and positioning hole 65. [0004] During the use of the PDMS micro flow cell, it needs to be attached to the installation surface and given a certain compression force. Whether t...

Claims

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Application Information

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IPC IPC(8): G01N33/00
Inventor 王晓萍庞凯张冰董伟洪夏云施春飞
Owner 浙江诺迦生物科技有限公司