A kind of preparation method of dendrobium oral ulcer buccal tablet

Abstract

The invention discloses a preparation method of a dendrobium nobile oral ulcer buccal tablet, and relates to the preparation method of the buccal tablet for treating oral ulcer. The invention aims to solve the problems that a conventional buccal tablet for treating oral ulcer mostly takes extracts extracted from bitter and astringent medicinal materials for tabletting and has poor mouthfeel when kept in mouth, the patient compliance is not good, the oral-taking bioavailability is low, and sucrose, starch and other auxiliary materials easily adhere on ulcer surfaces, so as to cause mass propagation of bacteria on the ulcer surfaces, resulting in difficult healing of the ulcer surfaces. The preparation method of the dendrobium nobile oral ulcer buccal tablet comprises the steps: 1, sieving raw and auxiliary materials; 2, weighing the raw and auxiliary materials; 3, mixing evenly the raw materials; 4, mixing evenly the auxiliary materials; 5, mixing evenly the raw materials with the auxiliary materials; and 6, directly tabletting to obtain the product. The buccal tablet prepared by adopting the extracts is good in mouthfeel, is high in bioavailability, enables effective components to be uniformly distributed on the ulcer surfaces, and plays roles in protecting wound surfaces and locally slow-releasing the drug. The preparation method adopts the modern advanced pharmaceutical equipment for directly tabletting, and is suitable for industrialized mass production.

Description

technical field [0001] The invention relates to a preparation method of Dendrobium oral ulcer buccal tablets used for treating oral ulcers. Background technique [0002] Buccal tablets have the advantages of convenient administration, high bioavailability and quick onset of action due to the absorption of some drugs through the mucous membrane without the first-pass effect of the liver. Therefore, in the field of treatment of oral ulcers, preparations are often made into buccal formulations. Dendrobium oral ulcer lozenges have the effects of nourishing yin and promoting blood circulation, clearing heat and detoxification, astringent and relieving pain, and are used to treat the central depression of the affected oral mucosa caused by oral ulcers. The surface is covered with a layer of light yellow pseudomembrane. Severe pain and may be accompanied by systemic symptoms such as local lymphadenopathy and fever. In recent years, due to the accelerated pace of life, excessive m...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the problem that the existing oral ulcer chemical drugs cannot fundamentally solve the oral ulcer, the existing traditional Chinese medicine varieties are inconvenient to use, the onset of effect is slow, the release of active ingredients is incomplete, the oral bioavailability is low, and the production There are too many process steps, high energy consumption in the production process, and relatively high pollutant discharge, thereby providing a preparation method for Dendrobium oral ulcer lozenges