Filled-type gas chromatographic column and preparation method thereof

Abstract

The invention provides a filled-type gas chromatographic column. The filled-type gas chromatographic column comprises a first substrate, a second substrate and a chromatographic packing. Micro-channels are processed on the surface of the first substrate. Micro-channels are processed on the surface of the second substrate. The position of the micro-channels on the surface of the second substrate is corresponding to the position of the micro-channels on the surface of the first substrate. After the first substrate and the second substrate are combined tightly, the micro-channels on first substrate and the micro-channels on second substrate together form chromatographic column micro-channels. The chromatographic packing is filled in the chromatographic column micro-channels. The filled-type gas chromatographic column is formed by mutual bonding of the two substrates. As the chromatographic column micro-channels are formed by the micro-channels on the surfaces of the two substrates, limit of corresponding dimensions is broken through, length is larger, and reliability is higher. The invention also provides a preparation method of the above filled-type gas chromatographic column.

Description

technical field [0001] The invention relates to the technical field of chromatography detection, in particular to a packed gas chromatography column and a preparation method thereof. Background technique [0002] For environmental air quality monitoring, environmental air quality monitoring in equipment, smart grid and oil exploration and other fields to pollute air (mainly CO, CO 2 , NO 2 , SO 2 、H 2 S, C1~C6 and other low-carbon hydrocarbons, etc.) are urgently needed for rapid and efficient separation and detection. The existing technology urgently needs micro gas chromatography columns to achieve fast and efficient separation of low-carbon compounds and permanent gases. [0003] And currently for CO, CO 2 , SO 2 , NO 2 、H 2 S, C1-C6 and other low-carbon hydrocarbons separation technologies and methods mostly use traditional capillary chromatographic columns and packed columns. These traditional chromatographic columns are not suitable for on-site monitoring due to...

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Problems solved by technology

[0005] But, there is certain defective in above-mentioned micro gas chromatographic column

First, the method of designing microcolumns in the channel can increase the surface area of ​​the channel, but it also limits the depth of the channel. From the above figure, it can be found that due to the limitation of processing technology, the greater the depth of the chromatographic channel, the greater the depth of the channel. The diameter of the micro-pillar becomes thinner and thinner. When the channel reaches 200 microns, it is close to the limit of the existence of the column. If it is deeper, the column will be easily broken; secondly, the fixed phase film (Al 2 o 3 ) is to coat the stationary phase on the surface of the channel and column by atomic deposition technology. The thickness of the stationary phase film is very limited, only 10nm, which is far smaller than the traditional range of 200nm-20000nm, which greatly limits the sample capacity and is difficult to apply Separation of complex mixtures; thirdly, the stationary phase is coated by atomic deposition technology, and the types of stationary phase materials that can be coated are very limited, which greatly limits its application in a wider range of fields

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