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A kind of natural medicinal composition for preventing and treating alcoholic liver injury and preparation method thereof
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A technology of alcoholic liver damage, natural medicine, applied in the field of medicine, to achieve the effect of improving the health of the body, hindering the formation of lipid peroxide, obvious innovation and technological progress
Active Publication Date: 2018-02-06
JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT
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Problems solved by technology
So far, there is no ideal drug to effectively prevent and treat the occurrence and development of liver diseases in clinical practice.
Method used
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Embodiment 1
[0049] Embodiment 1, Preparation of total triterpene acids from loquat leaves
[0050] (1) Loquat leaves 5kg, decocted with 10 times the amount of water to extract twice, each time for 2 hours, filtered, combined the filtrate for later use; dregs were extracted twice with 6 times the amount of 80% ethanol, each time for 2 hours, filtered, Combine the filtrates, add 400g of medicinal activated carbon, stir, filter, and recover ethanol from the filtrate, concentrate, filter, and dry the filter cake to obtain the total triterpene acids of loquat leaves.
Embodiment 2
[0051] Example 2 , Preparation of total flavonoids from loquat leaves
[0052] (2) Concentrate the water extract of loquat leaves to 7500ml, pass through the pre-treated AB-8 macroporous resin column, elute with deionized water for 4 times the column volume, discard the eluent, and then wash with 60% ethanol Remove 5 times the column volume, collect the eluate, recover ethanol, and dry to obtain the total flavonoids of loquat leaves.
Embodiment 3
[0053] Example 3 1. Preparation of total flavonoids from loquat leaves 5 kg of sarcodon grape leaves, reflux extraction with 8 times the amount of 60% ethanol for 2 times, each time for 3 hours, filter, the filtrate reclaims ethanol, concentrates to 7500ml, and passes through the pre-treated AB-8 large Porous resin column, first elute with deionized water for 5 times the column volume, discard the eluent, then elute with 10% ethanol for 3 times the column volume, discard the eluent, and then elute with 65% ethanol for 4 times the column volume volume, collect the eluate, recover ethanol, and dry to obtain the total flavonoids of S. dentatus grape.
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Abstract
The invention relates to a natural medicine composition for relieving alcohol and protecting the liver. The composition is composed of total triterpene acids of loquat leaves, total flavonoids of loquat leaves, total flavonoids of japonica grape and corn silk extract. The invention also relates to the application of the composition in preparing health food for preventing and treating acute and chronic alcoholicliver injury and in preparing health food or beverage for treating non-alcoholic fatty liver. The various components of the composition of the invention produce good synergistic effects, have remarkable curative effect, and the raw materials are easy to obtain, the cost is relatively low, and the composition has strong practicability.
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