A kind of natural medicinal composition for preventing and treating alcoholic liver injury and preparation method thereof

A technology of alcoholic liver damage, natural medicine, applied in the field of medicine, to achieve the effect of improving the health of the body, hindering the formation of lipid peroxide, obvious innovation and technological progress

Active Publication Date: 2018-02-06
JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, there is no ideal drug to effectively prevent and treat the occurrence and development of liver diseases in clinical practice.

Method used

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  • A kind of natural medicinal composition for preventing and treating alcoholic liver injury and preparation method thereof
  • A kind of natural medicinal composition for preventing and treating alcoholic liver injury and preparation method thereof
  • A kind of natural medicinal composition for preventing and treating alcoholic liver injury and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Embodiment 1, Preparation of total triterpene acids from loquat leaves

[0050] (1) Loquat leaves 5kg, decocted with 10 times the amount of water to extract twice, each time for 2 hours, filtered, combined the filtrate for later use; dregs were extracted twice with 6 times the amount of 80% ethanol, each time for 2 hours, filtered, Combine the filtrates, add 400g of medicinal activated carbon, stir, filter, and recover ethanol from the filtrate, concentrate, filter, and dry the filter cake to obtain the total triterpene acids of loquat leaves.

Embodiment 2

[0051] Example 2 , Preparation of total flavonoids from loquat leaves

[0052] (2) Concentrate the water extract of loquat leaves to 7500ml, pass through the pre-treated AB-8 macroporous resin column, elute with deionized water for 4 times the column volume, discard the eluent, and then wash with 60% ethanol Remove 5 times the column volume, collect the eluate, recover ethanol, and dry to obtain the total flavonoids of loquat leaves.

Embodiment 3

[0053] Example 3 1. Preparation of total flavonoids from loquat leaves 5 kg of sarcodon grape leaves, reflux extraction with 8 times the amount of 60% ethanol for 2 times, each time for 3 hours, filter, the filtrate reclaims ethanol, concentrates to 7500ml, and passes through the pre-treated AB-8 large Porous resin column, first elute with deionized water for 5 times the column volume, discard the eluent, then elute with 10% ethanol for 3 times the column volume, discard the eluent, and then elute with 65% ethanol for 4 times the column volume volume, collect the eluate, recover ethanol, and dry to obtain the total flavonoids of S. dentatus grape.

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PUM

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Abstract

The invention relates to a natural medicine composition for relieving alcohol and protecting the liver. The composition is composed of total triterpene acids of loquat leaves, total flavonoids of loquat leaves, total flavonoids of japonica grape and corn silk extract. The invention also relates to the application of the composition in preparing health food for preventing and treating acute and chronic alcoholic liver injury and in preparing health food or beverage for treating non-alcoholic fatty liver. The various components of the composition of the invention produce good synergistic effects, have remarkable curative effect, and the raw materials are easy to obtain, the cost is relatively low, and the composition has strong practicability.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a composition with natural products for preventing and treating alcoholic liver injury and other related diseases. Background technique [0002] Alcoholic liver damage (ALD) is a toxic liver disease caused by long-term excessive drinking, and ALD is the leading cause of liver cirrhosis in patients in Western countries. In my country, alcoholic liver disease has gradually increased in recent years, and has become the second largest cause of liver disease after viral hepatitis. [0003] Alcoholic liver disease is a liver disease caused by long-term heavy drinking. It usually manifests as fatty liver at the initial stage, and then can develop into alcoholic hepatitis, alcoholic liver fibrosis and alcoholic cirrhosis. Severe alcoholism can induce extensive liver cell necrosis or even Liver failure. Up to now, there is no ideal medicine to effectively prevent and treat the occurr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/899A23L33/00A23L2/38A23F3/34A23G3/48A61P1/16
Inventor 胡铭南敏伦郝玉芳候宝王连萍赵宝琴赵全成
Owner JILIN MODERN TRADITIONAL CHINESE MEDICINE ENG RES CENT
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