Medicine for treating ankylosing spondylitis and preparation method of medicine

A technology for ankylosing spondylitis and drugs, which is applied in the directions of drug combinations, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve the problems of low positive rate of rheumatoid factor, dependence and side effects, and unfavorable long-term use. , to achieve the effect of no toxic side effects, exact curative effect and short treatment course

Inactive Publication Date: 2015-11-11
吴强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] 2. Immunological examination: the positive rate of rheumatoid factor is not high
However, the above-mentioned drugs all have certain toxicity, are not conducive to long-term use, and are often used to have dependence and side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0060] When the dosage form of the medicine is ointment, its preparation method may further comprise the steps:

[0061] The first step is to mix the raw materials of the drug in proportion, crush them into powders of 40 mesh to 60 mesh, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixture, and heat to reflux for 1 to 3 hours , extract, and filter to obtain the first extract; the medicinal dregs obtained by filtering are then added with ethanol with an alcohol concentration of 85-95% relative to the mass of the medicinal dregs, which is 1 to 2 times the mass of the medicinal dregs, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain The second extract: combining the first extract and the second extract, concentrating under reduced pressure to remove the ethanol solvent, drying to obtain a dry paste, and pulverizing into a powder of 100 mesh to 200 mesh;

[0062] In the second step, stearic acid is heated and melted and...

Embodiment 1

[0067] Embodiment 1 Ointment 1

[0068] The preparation process of the ointment of the present invention is as follows: take 400g of cinnamon bark, 30g of cassia bark, 240g of medlar, 150g of Digupi, 320g of weed grass, 150g of madder root, 360g of cypress branch, 140g of Puhuang, 250g of cassia twig, 420g, 230g Chuanxiong, 170g iron-clad gold, 300g Hubu jingucao, 140g cow horse vine, 250g triangular vine, 420g xiaojingu vine, 30g cannabis medicine, 340g copper hammer jade belt grass, 220g deer medicine, 280g diapsis, 400g achyranthes bidentata And 200g of stretch grass;

[0069] The first step is to mix the raw materials of the drug in proportion, crush them into 45 mesh powder, add ethanol with an alcohol concentration of 90% that is 2.5 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract The medicinal dregs obtained by filtering are then added with 85% ethanol with an alcohol concentration of 1.5 times the quality of ...

Embodiment 2

[0072] Embodiment 2 Ointment 2

[0073] The preparation process of the ointment of the present invention is as follows: take 400g of cinnamon bark, 30g of cassia bark, 240g of medlar, 150g of Digupi, 320g of weed grass, 150g of madder root, 360g of cypress branch, 140g of Puhuang, 250g of cassia twig, 420g, 230g Chuanxiong, 170g iron-clad gold, 300g Hubu jingucao, 140g cow horse vine, 250g triangular vine, 420g xiaojingu vine, 30g cannabis medicine, 340g copper hammer jade belt grass, 220g deer medicine, 280g diapsis, 400g achyranthes bidentata , 200g Shenjincao, 30g Iris, 260g Cauliflower, 140g Yulongbian, 320g Mutouhui and 180g Qiannianjian;

[0074] The first step is to mix the raw materials of the drug in proportion, crush them into 50-mesh powder, add ethanol with an alcohol concentration of 95% that is 3 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract The medicinal residue obtained by filtering is then added wi...

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PUM

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Abstract

The invention discloses a medicine for treating ankylosing spondylitis and a preparation method of the medicine. The medicine comprises various active pharmaceutical ingredient as follows: herb of rice galingale, cassia bark, boxthorn fruit, cortex lycii radicis, arthraxon hispidus, rubia tinctorum madder root, corydalis cheilanthifolia, cattail pollen, cassia twig, radix rhapontici, Szechuan lovage rhizome, berchemia lineata, whitebracteole bugle herb, root or stem of evergreen mucuna, jamaica falsevalerian herb, rhizoma sparganii, tripterospermum volubile, falcate dolichos root or leaf, common pratia herb, diversifolious patrinia root, irid, smilacina japonica, teasel root, fructus leonuri, achyranthes bidentata, homalomena occulta and common clubmoss herb. The medicine has the efficacies of nourishing the liver and kidney, dispelling wind to eliminate dampness, and strengthening muscles and bones, together with the functions of dredging collaterals and activating blood circulation to remove blood stasis, and has the advantages of being instant in effect, high in effective rate, exact in treatment effect, short in treatment course, free of toxic or side effect, and low in price.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating ankylosing spondylitis and a preparation method thereof. Background technique [0002] Ankylosing spondylitis (AS) is a common disease in orthopedics and rheumatology. The main symptoms are sacroiliac joint and spinal attachment point inflammation. Lesion characteristics, is an autoimmune disease. In the early stage of the lesion, there is inflammatory pain in the joints, accompanied by muscle spasm around the joints, and a sense of stiffness, which is obvious in the morning. It can also be manifested as night pain, which is relieved by activities or taking analgesics. As the disease progresses, the joint pain is relieved, while the activities of the spinal segments and joints are limited and deformed. In the late stage, the entire spine and lower limbs become stiff arched and flexed forward. [0003] Symptoms and signs of ankylosi...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/902A61P19/08A61P19/02
Inventor 于春华于增智吴强
Owner 吴强
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