Traditional Chinese medicine gelling agent for treating superficial ulcer stage pressure sores and preparation method thereof

The technology of a gel and traditional Chinese medicine is applied to the traditional Chinese medicine gel for treating pressure ulcers in the shallow ulcer stage and the field of preparation thereof, and can solve the problems of sterilization and anti-inflammatory, muscle regeneration, sore astringency and ventilation, poor drainage effect, unsatisfactory treatment effect, etc. question

Inactive Publication Date: 2015-12-02
陈红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the bad effect of the medicine on sterilizing and anti-inflammation, promoting muscle regeneration, astringing sores, ventilating, and drainage, the therapeutic effect is not satisfactory.

Method used

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  • Traditional Chinese medicine gelling agent for treating superficial ulcer stage pressure sores and preparation method thereof
  • Traditional Chinese medicine gelling agent for treating superficial ulcer stage pressure sores and preparation method thereof
  • Traditional Chinese medicine gelling agent for treating superficial ulcer stage pressure sores and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Effect of the amount of acrylic acid-sodium acrylate-acrylamide copolymer on the gelling agent

[0074] Prescription: 47 parts by weight clear ointment and the gel base of 260 parts by weight

[0075] Clear paste raw materials are made (parts by weight): 11 parts of mulberry branch, 28 parts of Sijiqing, 10 parts of chrysanthemum, 15 parts of Speranthema, 12 parts of red bean, 15 parts of June Snow, 10 parts of Cartilage Mountain Dragon, horsetail Even 12 servings.

[0076] Preparation method of clear cream: mix mulberry branch, Sijiqing, Chuanshiteng, Speranthema, red bean, Liuyuexue, cartilage Guoshanlong, and horsetail, add water and boil for 2 to 3 times, and the amount of water added each time is as described 6 to 10 times the weight of the raw material drug, decocting time is 1 to 2 hours, filter; combine the filtrate, let it stand, take the supernatant and concentrate to a relative density of 1.05 to 1.10 (measured at 60 ° C), add ethanol to make the ethanol Th...

Embodiment 2

[0083] Prescription: 50 parts by weight of clear cream and 260 parts by weight of the gel matrix;

[0084] Clear paste raw materials are made (parts by weight): 11 parts of mulberry branch, 28 parts of Sijiqing, 10 parts of chrysanthemum, 15 parts of Speranthema, 12 parts of red bean, 15 parts of June Snow, 10 parts of Cartilage Mountain Dragon, horsetail Even 12 copies;

[0085] Gel matrix (parts by weight): 40 parts of carbomer (940), 6 parts of acrylic acid-sodium acrylate-acrylamide copolymer, 178 parts of glycerin, 7 parts of preservative ethylparaben, 4 parts of penetration enhancer Azone , 35 parts of 95% (v / v) ethanol and 410 parts of purified water.

[0086] Preparation method: mix mulberry twigs, Sijiqing, Chuanshiteng, Tugucao, red beans, Liuyuexue, cartilage Guoshanlong, and horsetail, add water and decoct for 2 to 3 times, and the amount of water added each time is the raw material drug 6 to 10 times the weight, decoct for 1 to 2 hours, filter; combine the filtr...

Embodiment 3

[0090] Prescription: 47 parts by weight of clear cream and 262 parts by weight of the gel matrix;

[0091] Clear paste raw material is made (parts by weight): 12 parts of mulberry branch, 30 parts of Sijiqing, 12 parts of chrysanthemum, 20 parts of Speranthema, 11 parts of red bean, 12 parts of June Snow, 12 parts of Cartilage Mountain Dragon, horsetail Even 10 copies;

[0092] Gel matrix (parts by weight): 37 parts of carbomer (940), 7 parts of acrylic acid-sodium acrylate-acrylamide copolymer, 174 parts of glycerin, 7 parts of preservative ethylparaben, 5 parts of penetration enhancer Azone , 36 parts of 95% (v / v) ethanol and 390 parts of purified water.

[0093] Preparation method: carry out with reference to Example 1-2.

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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine gelling agent for treating superficial ulcer stage pressure sores and a preparation method thereof. Clear paste used in the traditional Chinese medicine gelling agent is prepared from the following raw materials: ramulus mori, purpleflower holly leaves, aristolochia impressinervis, caulis impatientis, red beans, serissa serissoide, akebia trifoliate and radix et rhizoma thalictri; the functions of clearing away heat and toxic materials, inducing diuresis for removing edema and expelling the stasis for the new are achieved, the prepared gelling agent is easy to smear and spread, has good affinity with skin, can slowly and stably release drugs, and is beneficial for improvement of the drug bioavailability. The traditional Chinese medicine gelling agent prepared by adopting the preparation method can also improve the wound peripheral microcirculation, improve regional blood flow, relieve inflammatory edema, regional tissue ischaemia and oxygen deficit, reduce inflammatory exudation, promote inflammatory absorption and resolution, does not cause skin allergy, and is safe in use.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating pressure sores, in particular to a traditional Chinese medicine gel for treating superficial ulcer stage pressure sores and a preparation method thereof. Background technique [0002] Pressure sores, also known as pressure ulcers, are one of the common clinical complications. They are soft tissue ulceration and necrosis caused by prolonged ischemia, hypoxia, and malnutrition, which affect blood circulation due to partial pressure on the human body for a long time. The occurrence of pressure sores will increase the pain of the patient, aggravate the condition, prolong the course of the disease, and in severe cases, it may cause sepsis and endanger the life of the patient. [0003] Pressure sores belong to the categories of "decubitus ulcers" and "bed sores" in Chinese medicine, and are more common in p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/87A61P17/02
Inventor 潘桂菊
Owner 陈红
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