Sample detection apparatus

Abstract

The invention relates to a sample detection apparatus, comprising a test strip. The test strip comprises a sample pad, a mark pad and a detection pad, wherein the mark pad is located at the lower stream of the sample pad, the detection pad is located at the lower stream of the mark pad. The sample detection apparatus further comprises a capturing pad which is located at the upper stream of the test strip and communicated with a liquid in the test strip, and may be connected or not connected with the test strip. According to the invention, since the capturing pad and an antibody on the capturing pad are separated into two parts, time and space for bonding between the antibody and a to-be-analyzed substance in the sample are increased; thus, bonding is more adequate, and in particular, for special samples, possibility of false positive results is eliminated, and detection accuracy is improved.

Description

technical field [0001] The invention relates to a device for detecting samples, especially a test strip for detecting samples. Background technique [0002] The technique of using the principle of immunological binding reaction to detect the presence or absence of analyte in a sample is widely used in various fields. It can be used to detect analytes in various biological samples (saliva, blood, urine, serum, sweat, etc.) to monitor diseases and human health conditions (early pregnancy, tumors, infectious diseases, drugs, etc.). The fundamental principle of this detection technology is based on the specific binding properties between immune molecules, such as antibody and antigen, hapten / antibody, biotin and anti-biotin, etc. In addition, many of these assays can be performed on solid media, such as commonly used lateral flow reagent strips, glass or plastic multiwell plates, immunochromatographic devices, and the like. Usually, some solid particles or chemical substances ...

AI Technical Summary

Problems solved by technology

[0006] In actual operation, this detection device has the following problems: For saliva samples that are viscous or have low water content and many foams, the antibodies in the capture pad (second reagent area) at the earliest stage cannot be completely eluted, that is, the samples Insufficient binding to the antibody on the capture pad, resulting in insufficient amount of antibody binding to the antigen in the labeling pad, so the color cannot be developed, resulting in false positives

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