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Traditional Chinese medicine composition for treating hypertension

A composition, a technology for hypertension, applied in directions such as drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve the problems of poor compatibility of ingredients, long treatment period, insignificant treatment effect for hypertensive patients with phlegm-dampness type, etc. The effect of excessive viscosity, regulating cAMP level, and inhibiting gastrointestinal motility

Inactive Publication Date: 2016-02-24
NANYANG INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned patents all have poor adaptability of compatible ingredients, long treatment cycle, and insignificant therapeutic effect on hypertensive patients with phlegm-heat or phlegm-dampness type.

Method used

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  • Traditional Chinese medicine composition for treating hypertension

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] An oral pharmaceutical composition for treating hypertension, comprising the following raw materials: 10g earthworm, 10g gentian, 45g solanum nigrum, 2g artificial bezoar, 8g Qingpinellia, 10g scutellaria baicalensis, 10g Zhiyuanzhi, 10g winter melon kernel And herb 10g.

[0052] The preparation method of the above-mentioned oral pharmaceutical composition for treating hypertension comprises the following steps:

[0053] (1) Take the raw materials of the above weight and add them to 6 times the amount of ethanol to soak for 2 hours, heat and extract 3 times, 1 hour each time, combine the extracts, filter with 100 mesh, and then ultrafilter through an ultrafiltration column with a cut-off molecular weight of 5000, the filtrate Concentrate under reduced pressure the extract whose relative density is 1.15 at 70°C, which is component A;

[0054] (2) Put the dregs of the raw material drug extracted with ethanol in step (1) into 8 times the amount of water, heat and reflux f...

Embodiment 2

[0057] An oral pharmaceutical composition for treating hypertension, comprising the following raw materials: 12g earthworm, 11g gentian, 46g solanum nigrum, 3g artificial bezoar, 12g Qingpinellia, 12g scutellaria baicalensis, 11g Zhiyuanzhi, 11g winter melon kernel and Cangzhu 11g.

[0058] The preparation method of the above-mentioned oral pharmaceutical composition for treating hypertension comprises the following steps:

[0059] (1) Take the raw materials of the above weight and add them to 8 times the amount of ethanol to soak for 1.5 hours, heat and extract 3 times, each time for 1.5 hours, combine the extracts, filter with 120 mesh, and then ultrafilter through an ultrafiltration column with a cut-off molecular weight of 6000 , the filtrate is concentrated under reduced pressure, and the extract with a relative density of 1.15 at 70°C is component A;

[0060] (2) Put the dregs of the crude drug extracted with ethanol in step (1) into 12 times the amount of water, heat a...

Embodiment 3

[0063] An oral pharmaceutical composition for treating hypertension, comprising the following raw materials: 13g of earthworm, 12g of gentian, 50g of nightshade, 5g of artificial bezoar, 15g of Qingpinellia, 15g of scutellaria baicalensis, 13g of Zhiyuanzhi, 13g of winter melon kernel and herb 15g.

[0064] The preparation method of the above-mentioned oral pharmaceutical composition for treating hypertension comprises the following steps:

[0065] (1) Take the raw material medicine of the above weight and add it to 7 times the amount of ethanol, soak for 1 hour, heat and extract twice, each time for 2 hours, combine the extracts, filter through 120 mesh, and then ultrafilter through an ultrafiltration column with a cut-off molecular weight of 10,000. The filtrate is concentrated under reduced pressure, and the extract with a relative density of 1.15 at 70°C is component A;

[0066] (2) Heat and reflux the medicinal dregs extracted in step (1) with 10 times the amount of wate...

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Abstract

The invention relates to a traditional Chinese medicine composition for treating hypertension. The traditional Chinese medicine composition comprises an oral pharmaceutical composition and an external pharmaceutical composition. The oral pharmaceutical composition comprises, by weight, 10-20 parts of lumbricus, 10-20 parts of Gentiana scabra Bunge, 45-60 parts of solanum nigrum, 2-8 parts of calculus bovis factitious, 8-17 parts of rhizoma pinelliae preparata, 10-20 parts of radix scutellariae, 10-19 parts of prepared polygala root, 10-20 parts of white gourd kernel and 10-20 parts of rhizoma atractylodis. The external pharmaceutical composition comprises 10-20 parts of Gentiana scabra Bunge, 20-30 parts of wine-treated rhubarb, 10-20 parts of motherwort, 10-25 parts of red peony root, 20-30 parts of achyranthes root, 20-30 parts of ligusticum wallichii, 20-30 parts of rhizoma sparganii, 20-35 parts of evodia, 10-20 parts of lumbricus and 40-60 parts of rice vinegar. Through internal adjustment and symptom treatment in the traditional Chinese medicine, the traditional Chinese medicine composition has good effects of treating phlegm heat-type or phlegm damp-type hypertension.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating hypertension. Background technique [0002] Hypertension is a systemic disease characterized by elevated arterial pressure, which may be accompanied by functional or organic changes in the heart, blood vessels, brain, and kidneys. According to the priority of onset and the progress of the disease, it can be divided into slow progressive type and rapid progressive type. The symptoms of hypertension vary from person to person. In the early stage, there may be no symptoms or no obvious symptoms. Blood pressure will only increase after fatigue, mental stress, and mood swings, and it will return to normal after rest. The common clinical symptoms of slow-progressive hypertension include headache, dizziness, and inattention. Concentration, memory loss, limb numbness, nocturia, palpitations, chest ...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61P9/12A61K35/413A61K35/62
Inventor 毛秉豫刘暖杨雷毛懋张千一孟媛
Owner NANYANG INST OF TECH
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