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Petroselinic acid or a combination of active ingredients comprising at least petroselinic acid for promoting weight loss and/or weight maintenance

A petroselinic acid and active agent technology, applied in the direction of inorganic active ingredients, organic active ingredients, anhydride/acid/halide active ingredients, etc., can solve problems that have not been raised

Inactive Publication Date: 2016-02-24
NESTEC SA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Thus, none of the prior art documents proposes that petroselinic acid or a combination of active agents comprising at least petroselinic acid and at least one selected from the group consisting of zinc, taurine, Compounds of their salts, lycopene and mixtures thereof

Method used

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  • Petroselinic acid or a combination of active ingredients comprising at least petroselinic acid for promoting weight loss and/or weight maintenance
  • Petroselinic acid or a combination of active ingredients comprising at least petroselinic acid for promoting weight loss and/or weight maintenance
  • Petroselinic acid or a combination of active ingredients comprising at least petroselinic acid for promoting weight loss and/or weight maintenance

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0117] Example 1 : Oral composition in the form of soft capsule

[0118]

[0119]

Embodiment 2

[0120] Example 2 : Oral composition as a stick in the form of an emulsion

[0121]

[0122]

Embodiment 3

[0123] Example 3 : Demonstration of the activating effect of petroselinic acid and the combination of petroselinic acid and lycopene on the synthesis / basal release of lipoxin A4 by keratinocytes according to the invention

[0124] In serum-free medium for macrophages (SFM Macrophage; Invitrogen12065074) in 5% CO 2 and 37°C, culture mononuclear blood cells for 24 hours.

[0125] After this step, as indicated in the table of results below, the medium was replaced for 30 minutes by the same fresh test medium, also containing the active agent in different doses, in the presence of each product to be evaluated. In phorbol myristate (0.05 μM) and calcium ionophore (1 μM) and composed of docosahexaenoic acid (DHA-1 μg / mL) and docosapentaenoic acid (EPA-1 μg / mL) In the presence of a lipid-substrate mixture, an inflammatory response is induced.

[0126] The supernatant was then collected after 2 hours of stimulation and then ready to freeze at -80°C prior to analysis by mass spectrom...

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Abstract

The present invention relates to the field of weight management and obesity. It concerns petroselinic acid or a combination of active ingredients comprising at least petroselinic acid and at least one compound chosen from zinc, taurine, one of the salts of same, lycopene and the mixtures thereof, and preferably at least taurine or zinc gluconate and, more preferably still, at least taurine and zinc gluconate, as a drug for oral administration or as a functional food intended to promote weight loss and / or weight maintenance in a human being and / or animal, or indeed intended to fight obesity.

Description

technical field [0001] The present invention finds use in the field of compositions accompanying weight management, promoting weight loss and / or weight maintenance in humans and / or animals. [0002] In particular, the present invention is directed to proposing the use of petroselinic acid, or at least a combination comprising petroselinic acid, for concomitant weight management, promotion of weight loss and / or weight maintenance in humans and / or animals. The petroselinic acid or combination of active agents considered in the context of the present invention is preferably used as a medicament or in a functional food. Background technique [0003] During weight gain, the formation of fat masses or the overgrowth of adipose tissue can evolve between purely localized overweight (lipid morphine) and hyperplasia, through specific levels of adiposity, and finally to true obesity. Obesity is a truly incapacitating pathological condition when it leads in particular to the developmen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/36A61K31/201A61P3/04
CPCA61K8/36A61Q19/06A61K31/01A61K31/185A61K33/30A61K35/744A61K36/06A61K2800/92A23L33/30A23L33/10A23L33/105A23L33/12A23L33/16A61K31/201A61K31/191A61K31/355A61K31/593A61K8/9728A61K8/9789A61P3/04A61K2300/00A23V2002/00A61K9/0053A61K36/23A61K45/06
Inventor 杨·马希卡罗尔·布鲁奥德丽·格尼什
Owner NESTEC SA
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