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Medical application of Hudi enteric capsules

An enteric-coated capsule and application technology, applied in new application fields, can solve problems such as side effects, affecting hormone secretion levels, etc.

Inactive Publication Date: 2016-03-23
安徽九方制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Long-term use of hormone drugs will affect the secretion level of the body's own normal hormones, resulting in serious side effects

Method used

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  • Medical application of Hudi enteric capsules
  • Medical application of Hudi enteric capsules
  • Medical application of Hudi enteric capsules

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0039] (1) Extraction (parts by mass) of active ingredients of traditional Chinese medicine composition

[0040] Take 30-70 parts of cinnabar seven, 30-70 parts of knotweed, 60-140 parts of Burnet, 60-140 parts of Limonium bicolor, 60-140 parts of Beibaijiang, 60-140 parts of Hedyotis diffusa, 30 parts of Baiji -60 parts, licorice 15-50 parts.

[0041] After the above eight flavors are mixed, add water and boil three times, add 10 times the amount of water for the first time, soak for 20 minutes, decoct for 3 hours, add 9 times the amount of water for the second time, decoct for 2 hours, and add 8 times the amount for the third time water, decocted for 1 hour, combined the decoction, filtered, the filtrate was concentrated under reduced pressure to a thick paste, dried, and crushed into fine powder.

[0042] (2) Animal experiments

[0043] Experimental unit: College of Radiation Medicine and Protection, Soochow University School of Medicine.

[0044] Now take the capsule as...

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Abstract

The invention provides medical application of Hudi enteric capsules, in particular to application of a traditional Chinese medicine compound composing the Hudi enteric capsules to preparation of medicine preventing radioactive intestinal injuries. The traditional Chinese medicine compound is prepared from, by mass, 10-100 parts of polygonum cillinerve (nakai) ohwi, 10-100 parts of polygonum cuspidatum, 20-200 parts of sanguisorba officinalis, 20-200 parts of limonium bicolor, 20-200 parts of patrinia scabiosaefolia, 20-200 parts of oldenlandia diffusa, 8-80 parts of rhizoma bletillae and 5-70 parts of liquorice. The survival rate of mice suffering from radioactive intestinal injuries can be increased by taking the Hudi enteric capsules before radiation, the absorbing function of the small intestines is protected, the intestinal mucosa is protected, and apoptosis of endothelial cells is reduced.

Description

1. Technical field [0001] The invention relates to a new application of a known substance, specifically a new medical application of Hudi enteric-coated capsules. 2. Background technology [0002] Chronic nonspecific ulcerative colitis, currently officially named by the World Health Organization as idiopathic colitis (specificcolitis) is a chronic disease of unknown cause, and immunity is the most concerned factor in recent years. The disease mainly invades the colon and rectum. For the lamina propria and submucosa, primary enteropathy with erosion and ulceration, modern medicine uses hormones, azosulfapyridine salicylate, immunosuppressants, disodium cromoglycate and antifibrinolytics, etc., but the time of medication Long, large side effects, high recurrence rate, so the curative effect is all unsatisfactory. [0003] For this reason, applied for the development of a Chinese patent medicine Hudi enteric-coated capsule, referred to as Hudi capsule, and applied for a Chines...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61K9/48A61P1/00
Inventor 宫彤林赵守田欧阳汉霖王建礼杨林路大勇谷先锋钟健郅立平杨小梅李玉梅李亚男
Owner 安徽九方制药有限公司
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