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New application of radix ranunculi ternate in preparation of medicine for treating and/or preventing ulcerative colitis

A technology of ulcerative colitis and cat's claw, which is applied to the new use of cat's claw polysaccharide, and the field of preparing medicines for treating and/or preventing ulcerative colitis, can solve the problems such as ulcerative colitis that have not yet existed, and the like, To effectively treat ulcerative colitis, increase the level of IL-4, and reduce the level of IL-1

Inactive Publication Date: 2016-04-20
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are no relevant reports on the use of cat's claw or cat's claw polysaccharides in the treatment of ulcerative colitis

Method used

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  • New application of radix ranunculi ternate in preparation of medicine for treating and/or preventing ulcerative colitis
  • New application of radix ranunculi ternate in preparation of medicine for treating and/or preventing ulcerative colitis
  • New application of radix ranunculi ternate in preparation of medicine for treating and/or preventing ulcerative colitis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Take 1kg of cat's claw herb, crush it, add water to extract twice, add 12 times the weight of the medicine for 3 hours at 100°C for the first time, add 10 times the weight of the medicine for 100°C for 2 hours, and combine the extracts , filtered to obtain the cat's claw extract.

Embodiment 2

[0039] Take 1 kg of cat's claw herb, crush it, and extract it with water for 3 times. For the first time, add 12 times the weight of the drug and extract at 70°C for 2 hours. Add water 8 times the weight of the medicinal materials and extract at 70°C for 1 hour, combine the extracts, and filter to obtain the extract of Cat's Claw.

Embodiment 3

[0041] Take 1kg of cat's claw herb, crush it, add water to extract twice, add 12 times the weight of the medicine for 3 hours at 100°C for the first time, add 10 times the weight of the medicine for 100°C for 2 hours, and combine the extracts , filtered to obtain the cat’s claw extract; heat and concentrate the cat’s claw extract to contain 700 g of medicinal materials per L of the concentrated solution, add 95% ethanol with a volume percentage of 1 times the concentrated solution’s weight, stir evenly, let stand for 5 hours, and obtain the precipitate Then wash twice with 95% ethanol which is 5 times the weight of the sediment, and dry to obtain the cat's claw polysaccharide.

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Abstract

The invention relates to a new application of radix ranunculi ternate, namely a new application of the radix ranunculi ternate in preparation of a preparation for treating and / or preventing ulcerative colitis, in particular to a new application of the radix ranunculi ternate in preparation of a medicine for treating and / or preventing the ulcerative colitis.

Description

technical field [0001] The present invention relates to the new application of cat's claw, especially the new application of cat's claw polysaccharide, that is, the new application in the preparation of medicines for treating and / or preventing ulcerative colitis. Background technique [0002] Ulcerative colitis (UC) is a chronic nonspecific inflammatory disease that occurs in the colon and rectum. Its onset age is relatively young, and its incidence is increasing year by year in my country. The etiology and pathogenesis of ulcerative colitis are still unclear. Traditional Chinese medicine started from the "Nei Jing" and has been supplemented and interpreted by generations of physicians. Modern medicine believes that it is mainly related to the interaction of immunity, infection, environment, genetics and other factors. Ulcerative colitis often has damage to the intestinal mucosal barrier, which leads to the entry of antigens and excessive immunity, which leads to a series of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/71A61K31/715A61P1/00C08B37/00
CPCA61K31/715A61K36/71A61K2236/331A61K2236/39A61K2236/53C08B37/00C08B37/0003
Inventor 刘冠萍吴赛春陈红严灿梅
Owner GUANGXI WUZHOU PHARMA GRP
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