Method for testing sulfamethoxazole in water by means of ion mobility spectrometer

Abstract

The invention provides a method for testing sulfamethoxazole in water by means of an ion mobility spectrometer. The method comprises the steps of preparing a sulfamethoxazole standard working solution with a preset concentration gradient, and placing the standard working solution into the ion mobility spectrometer to obtain the ion mobility spectrogram of the standard working solution and the sulfamethoxazole standard curve; preparing a sample solution to be tested, and placing the sample solution into the ion mobility spectrometer to obtain the ion mobility spectrogram of the sample solution to be tested; comparing the ion mobility spectrogram of the sample solution with the ion mobility spectrogram of the standard working solution, and calculating the actual content of sulfamethoxazole in the sample solution to be tested according to the sulfamethoxazole standard curve. By the adoption of the method, the content of sulfamethoxazole in water is obtained easily and conveniently by means of the ion mobility spectrometer, time consumption is low, and the test result is accurate.

Description

technical field [0001] The invention relates to the technical field of sulfamethoxazole detection, in particular to a method for detecting sulfamethoxazole in water using an ion mobility spectrometer. Background technique [0002] Sulfamethoxazole is a broad-spectrum antibiotic. The chemical name is: 3-p-aminobenzenesulfonamido-5-methyloxazole (C10H11N3O3S), CAS number: 723-46-6. It has inhibitory effect on most Gram-positive and Gram-negative bacteria. It is mainly used for urinary tract infection, respiratory system infection, intestinal infection, biliary tract infection and local soft tissue or wound infection caused by sensitive bacteria. [0003] The residue of PPCPs in pharmaceuticals and personal care products in the water environment is one of the important research projects in the current environmental field. my country is a big country in the production and use of antibiotics. The production and use of sulfonamide antibiotics are increasing significantly. The u...

AI Technical Summary

Problems solved by technology

This is because the above-mentioned liquid phase methods all have cumbersome pretreatments, such as samples generally need to go through solid-phase extraction columns and enrichment, so more chemical reagents and equipment are used, and the chromatographic ultraviolet and chromatographic mass spectrometers are expensive, resulting in maintenance higher cost

At the same time, the liquid phase method has high requirements for experimental instruments and equipment, complicated operation, high requirements for the professional knowledge of experimenters, and is time-consuming and laborious.

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