Ion mobility spectrometer for simultaneously monitoring propofol and sulfur hexafluoride in expired air and application

Abstract

Based on an ion mobility spectrometry technology, the invention design designs an ion mobility spectrometer for simultaneously monitoring propofol and sulfur hexafluoride in expired air, which is used for noninvasive online monitoring on a depth of anesthesia and a heart blood output of an intraoperative patient.

Description

technical field [0001] Based on ion mobility spectrometry technology, the present invention designs an ion mobility spectrometer for simultaneous monitoring of propofol and sulfur hexafluoride in exhaled air, which is used for online monitoring of patients' anesthesia depth and cardiac output during surgery. Background technique [0002] Propofol is a commonly used intravenous anesthetic, which has been widely used in induction of anesthesia, maintenance of anesthesia and sedation of critically ill patients in ICU. During the operation, the concentration of propofol in the patient's blood is often closely related to the depth of anesthesia. Therefore, monitoring the concentration of propofol in the patient's body during the operation is of great significance for anesthesia monitoring. However, for the determination of propofol in blood, methods such as high performance liquid chromatography and gas chromatography-mass spectrometry are usually used; blood, as a complex biolog...

AI Technical Summary

Problems solved by technology

Exogenous gases usually contain sulfur hexafluoride, and mass spectrometry is often used for its determination. However, mass spectrometers are often large in size and expensive, and it is not easy to promote them in clinical practice.

Images