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Medicinal composition with sleep improvement effect and preparation method for medicinal composition

A technology for improving sleep and composition, which is applied in the field of pharmaceutical composition with sleep-improving function and its preparation, and can solve problems such as rebound phenomenon, increased stroke, and cerebral vasoconstriction

Inactive Publication Date: 2016-07-20
DOUBLE RIDER MEDICINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the treatment of insomnia in western medicine generally includes benzodiazepines, barbiturates and other non-barbiturates. Long-term use can easily lead to drug dependence, and it is usually necessary to increase the dosage to maintain the effect. If the drug is stopped, rebound and withdrawal symptoms may occur, so it is not suitable for long-term use
At present, the safety of melatonin, which is widely used, has been controversial. Some researchers believe that taking high doses of pineal gland may promote cerebral vasoconstriction and increase the risk of stroke.

Method used

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  • Medicinal composition with sleep improvement effect and preparation method for medicinal composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] A pharmaceutical composition with the function of improving sleep, comprising the following components in parts by weight: 10 parts of Suanzaoren extract, 10 parts of Ciwujia extract, 10 parts of Poria cocos extract, 10 parts of Baiziren extract, 5 parts Polygala extract, 5 parts Schisandra extract.

[0061] A pharmaceutical composition with the function of improving sleep, wherein the jujube seed extract is obtained through the following steps:

[0062] (1) Weigh the dried jujube kernels, grind them, and pass through a 50-mesh sieve to get the jujube kernel powder;

[0063] (2) Pour jujube seed powder into the extractor, add 1 times the weight of ether and 5 times the weight of water, heat to 80-100°C, reflux for 2 hours, filter, repeat this operation once, and combine the filtrates twice;

[0064] (3) Concentrate the filtrate to a relative density of 1.03, and dry it in an oven at a temperature of 50-60°C to obtain the jujube seed extract.

[0065] A pharmaceutical ...

Embodiment 2

[0091] A pharmaceutical composition for improving sleep, comprising the following components in parts by weight: 30 parts of Suanzaoren extract, 30 parts of Ciwujia extract, 20 parts of Poria cocos extract, 20 parts of Baiziren extract, 10 parts Polygala extract, 15 parts Schisandra extract.

[0092] A pharmaceutical composition with the function of improving sleep, wherein the jujube seed extract is obtained through the following steps:

[0093] (1) Weigh the dried jujube kernels, grind them, and pass through an 80-mesh sieve to get the jujube kernel powder;

[0094] (2) Pour jujube seed powder into the extractor, add 2 times the weight of ether and 8 times the weight of water, heat to 80-100°C, reflux for 2 hours, filter, repeat this operation once, and combine the two filtrates;

[0095] (3) Concentrate the filtrate to a relative density of 1.04, and dry it in an oven at a temperature of 50-60°C to obtain the jujube seed extract.

[0096] A pharmaceutical composition with...

Embodiment 3

[0122] A pharmaceutical composition with the function of improving sleep, comprising the following components in parts by weight: 50 parts of Suanzaoren extract, 50 parts of Ciwujia extract, 30 parts of Poria cocos extract, 30 parts of Baiziren extract, 20 parts Polygala extract, 20 parts Schisandra extract.

[0123] A pharmaceutical composition with the function of improving sleep, wherein the jujube seed extract is obtained through the following steps:

[0124] (1) Weigh the dried jujube kernels, grind them, and pass through a 100-mesh sieve to get the jujube kernel powder;

[0125] (2) Pour jujube seed powder into the extractor, add 3 times the weight of ether and 10 times the weight of water, heat to 80-100°C, reflux for 2 hours, filter, repeat this operation once, and combine the two filtrates;

[0126] (3) The filtrate is concentrated to a relative density of 1.05, and dried in an oven at a temperature of 50-60° C. to obtain the jujube seed extract.

[0127] A pharmaceut...

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Abstract

The invention discloses a medicinal composition with a sleep improvement effect and a preparation method for the medicinal composition. The medicinal composition is prepared from 10 to 50 parts of semen ziziphi spinosae extract, 10 to 50 parts of eleutherococcus senticosus extract, 10 to 30 parts of poria cocos extract, 10 to 30 parts of platycladi seed extract, 5 to 20 parts of polygala tenuifolia extract and 5 to 20 parts of schisandra extract. The defect that as drug dependence is easily resulted from long-term usage of a western drug, the western drug is unsuitable to be taken for long is overcome, and multiple drugs are combined to complement one another and synergistically achieve the effects of tranquilizing the mind by nourishing the heart, clearing away the heart fire, relieving restlessness and resolving depression, so as to achieve the aim of improving sleep.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine health products, in particular to a pharmaceutical composition with the function of improving sleep and a preparation method thereof. Background technique [0002] Insomnia is a common disease. With the acceleration of the pace of life in modern society, the incidence of insomnia in the crowd is increasing year by year. Insomnia can cause symptoms such as lack of energy, fatigue, dizziness, and irritability in patients, which seriously affects people's health, work and life. [0003] At present, the treatment of insomnia in western medicine generally includes benzodiazepines, barbiturates and other non-barbiturates. Long-term use can easily lead to drug dependence. Usually, it is necessary to increase the dosage of the drug to maintain the effect. If the drug is stopped, rebound and withdrawal symptoms may occur, so it is not suitable for long-term use. At present, the safet...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/725A61P25/20
CPCA61K36/725A61K36/076A61K36/14A61K36/254A61K36/57A61K36/69A61K36/79A61K2236/331A61K2236/35A61K2236/37A61K2236/39A61K2236/51A61K2236/55A61K2300/00
Inventor 曹正洪吴九妹邱俊生
Owner DOUBLE RIDER MEDICINE CO LTD
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