Method of nanometer zirconia toughened titanium alloy orthopedics implant based on 3D printing

Abstract

The invention discloses a preparation method of a nanometer zirconia particle toughened biological titanium alloy porous artificial implant. The preparation method is characterized by comprising the following steps: (1) preparation of nanometer / micron mixed powder: nanometer zirconia powder with a mass fraction of 0.5-8% is weighed and added in remained micron-grade titanium alloy powder, and the two powder is uniformly mixed by using a mechanical mixing method, wherein the particle size of the titanium alloy powder is 1-50 microns, and the purity is not lower than 99%; the size of the zirconia powder is 10-100 nm; and zirconia contains a yttrium oxide stabilizing agent with 1-5% of the mass of the zirconia powder; and (2) a matched porous artificial implant model is designed according to different personal demands by using three-dimensional design software; the designed three-dimensional data model is introduced in a computer for layering and slicing to obtain profile information of each layer; the mechanically mixed powder is paved on a forming cylinder by using a powder paving device; and the area selective melting formation is performed by using laser or electronic beams. The implant has the characteristics of good toughness and high biological compatibility.

Description

technical field

[0001] The present invention relates to a method for preparing an orthopedic implant, in particular to a method for preparing an orthopedic implant with increasing function, specifically a nano-zirconia toughened titanium alloy orthopedic implant based on 3D printing way of things. Background technique

[0002] Since the advent of artificial implants, millions of patients suffering from orthopedic diseases have been guaranteed to improve their living conditions and reintegrate into society. Artificial implants must have good biocompatibility, suitable mechanical properties and sufficient service life. However, the traditional artificial implant manufacturing method has a long manufacturing cycle and cannot be customized, and its biocompatibility and mechanical properties cannot be well satisfied. Therefore, it is necessary to develop more suitable artificial implant materials and preparation methods.

[0003] Titanium alloy materials are widely used in the...

Examples

Embodiment 1

[0030] A kind of preparation method of nano zirconia particle strengthening and toughening bio-titanium alloy porous artificial implant, it comprises the following steps:

[0031] (1) Use an electronic balance to accurately weigh 2.5g of nanometer yttrium oxide partially stabilized zirconia powder (the stabilizer yttrium oxide content is 2%, that is, the weight of yttrium oxide is 0.05g) and 47.5g of particle size is 20-50μm The titanium alloy powder TC4 was used, and the two powders were mixed uniformly by mechanical mixing, and finally a zirconia / titanium alloy TC4 composite powder with a mass fraction of zirconia of 5% was prepared.

[0032] (2) Use the Solidworks 3D design software to design the structure of the artificial implant, import the designed 3D data model into the computer for layered slicing, and then spread the mixed powder on the forming cylinder on the laser selective melting equipment. The thickness of the powder is 30-50 μm, and the laser is used for region...

Embodiment 2

[0035]A kind of preparation method of nano zirconia particle strengthening and toughening bio-titanium alloy porous artificial implant, it comprises the following steps:

[0036] (1) Use an electronic balance to accurately weigh 0.25g of nanometer yttrium oxide partially stabilized zirconia powder (the stabilizer yttrium oxide content is 1%, that is, the weight of yttrium oxide is 0.0025g) and 49.75g of particle size is 1-30μm Titanium alloy powder TC4, the two powders were mixed uniformly by mechanical mixing method, and finally a zirconia / titanium alloy TC4 composite powder with a mass fraction of zirconia of 0.5% was prepared.

[0037] (2) Use the Solidworks 3D design software to design the structure of the artificial implant, import the designed 3D data model into the computer for layered slicing, and then spread the mixed powder on the forming cylinder on the laser selective melting equipment. The thickness of the powder is 30-50 μm, and the laser is used for regional sel...

Embodiment 3

[0040] A kind of preparation method of nano zirconia particle strengthening and toughening bio-titanium alloy porous artificial implant, it comprises the following steps:

[0041] (1) Use an electronic balance to accurately weigh 4g of nanometer yttrium oxide partially stabilized zirconia powder (the stabilizer yttrium oxide content is 5%, that is, the weight of yttrium oxide is 0.2 grams) and 46g of titanium with a particle size of 30-50μm For the alloy powder TC4, the two powders were mixed uniformly by mechanical mixing, and finally a zirconia / titanium alloy TC4 composite powder with a mass fraction of zirconia of 8% was prepared.

[0042] (2) Use the Solidworks 3D design software to design the structure of the artificial implant, import the designed 3D data model into the computer for layered slicing, and then spread the mixed powder on the forming cylinder on the laser selective melting equipment. The thickness of the powder is 30-50 μm, and the laser is used for regional...

technical field

[0001] The present invention relates to a method for preparing an orthopedic implant, in particular to a method for preparing an orthopedic implant with increasing function, specifically a nano-zirconia toughened titanium alloy orthopedic implant based on 3D printing way of things. Background technique

[0002] Since the advent of artificial implants, millions of patients suffering from orthopedic diseases have been guaranteed to improve their living conditions and reintegrate into society. Artificial implants must have good biocompatibility, suitable mechanical properties and sufficient service life. However, the traditional artificial implant manufacturing method has a long manufacturing cycle and cannot be customized, and its biocompatibility and mechanical properties cannot be well satisfied. Therefore, it is necessary to develop more suitable artificial implant materials and preparation methods.

[0003] Titanium alloy materials are widely used in the...

Examples

Embodiment 1

[0030] A kind of preparation method of nano zirconia particle strengthening and toughening bio-titanium alloy porous artificial implant, it comprises the following steps:

[0031] (1) Use an electronic balance to accurately weigh 2.5g of nanometer yttrium oxide partially stabilized zirconia powder (the stabilizer yttrium oxide content is 2%, that is, the weight of yttrium oxide is 0.05g) and 47.5g of particle size is 20-50μm The titanium alloy powder TC4 was used, and the two powders were mixed uniformly by mechanical mixing, and finally a zirconia / titanium alloy TC4 composite powder with a mass fraction of zirconia of 5% was prepared.

[0032] (2) Use the Solidworks 3D design software to design the structure of the artificial implant, import the designed 3D data model into the computer for layered slicing, and then spread the mixed powder on the forming cylinder on the laser selective melting equipment. The thickness of the powder is 30-50 μm, and the laser is used for region...

Embodiment 2

[0035]A kind of preparation method of nano zirconia particle strengthening and toughening bio-titanium alloy porous artificial implant, it comprises the following steps:

[0036] (1) Use an electronic balance to accurately weigh 0.25g of nanometer yttrium oxide partially stabilized zirconia powder (the stabilizer yttrium oxide content is 1%, that is, the weight of yttrium oxide is 0.0025g) and 49.75g of particle size is 1-30μm Titanium alloy powder TC4, the two powders were mixed uniformly by mechanical mixing method, and finally a zirconia / titanium alloy TC4 composite powder with a mass fraction of zirconia of 0.5% was prepared.

[0037] (2) Use the Solidworks 3D design software to design the structure of the artificial implant, import the designed 3D data model into the computer for layered slicing, and then spread the mixed powder on the forming cylinder on the laser selective melting equipment. The thickness of the powder is 30-50 μm, and the laser is used for regional sel...

Embodiment 3

[0040] A kind of preparation method of nano zirconia particle strengthening and toughening bio-titanium alloy porous artificial implant, it comprises the following steps:

[0041] (1) Use an electronic balance to accurately weigh 4g of nanometer yttrium oxide partially stabilized zirconia powder (the stabilizer yttrium oxide content is 5%, that is, the weight of yttrium oxide is 0.2 grams) and 46g of titanium with a particle size of 30-50μm For the alloy powder TC4, the two powders were mixed uniformly by mechanical mixing, and finally a zirconia / titanium alloy TC4 composite powder with a mass fraction of zirconia of 8% was prepared.

[0042] (2) Use the Solidworks 3D design software to design the structure of the artificial implant, import the designed 3D data model into the computer for layered slicing, and then spread the mixed powder on the forming cylinder on the laser selective melting equipment. The thickness of the powder is 30-50 μm, and the laser is used for regional...